Drug Delivery

Catalogue Number:B399750Chemical Name:BiriperoneSynonyms:(±)-1-(4-Fluorophenyl)-4-(3,4,6,7,12,12a-hexahydropyrazino[1′,2′:1,6]pyrido[3,4-b]indol-2(1H)-yl)-1-butanone; 2-[4-(4-Fluorophenyl)-4-oxobutyl]-1,2,3,4,6,7,12,12a-octahydropyrazino[2′,1′:6,1]pyrido[3,4-b]indole; Centbutindole; NSC 14369;CAS Number:42021-34-1Molecular Formula:C₂₄H₂₆FN₃OAppearance:Off-White to Beige SolidMelting Point:>168°C (dec.)Molecular Weight:391.48Storage:4°CSolubility:Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Sonicated)Category:Research Tools; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Tryptamines;Applications:Biriperone, has shown D1, D2 and 5-HT2A receptor blocking activity. It is a potential neuroleptic agent.References:Chakrabarty, R., et al.: Bioorg. Med. Chem., 15 (23), 7361 […]

Catalogue Number:B399730Chemical Name:BirinapantSynonyms:TL 32711; (2S,2’S)-N,N’-[(6,6′-Difluoro[2,2′-bi-1H-indole]-3,3′-diyl)bis[methylene[(2R,4S)-4-hydroxy-2,1-pyrrolidinediyl][(1S)-1-ethyl-2-oxo-2,1-ethanediyl]]]bis[2-(methylamino)propanamideCAS Number:1260251-31-7Molecular Formula:C₄₂H₅₆F₂N₈O₆Appearance:White to Off-White SolidMelting Point:>245ºC (dec.)Molecular Weight:806.94Storage:-20°CSolubility:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)Category:Research Tools; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Birinapant is a bivalent SMAC mimetic compound antagonist of TRAF2 associated cIAP1 and cIAP2.References:Benetatos, C.A., et. al.: Mol. Cancer Ther., 13, 867 (2014)To ensure the stability of our products, the efficient express […]

Catalogue Number:B399710Chemical Name:BIRT 377Synonyms:(5R)-5-[(4-bromophenyl)methyl]-3-(3,5-dichlorophenyl)-1,5-dimethyl-2,4-Imidazolidinedione;CAS Number:213211-10-0Molecular Formula:C₁₈H₁₅BrCl₂N₂O₂Molecular Weight:442.13Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:BIRT 377 inhibits lymphocyte function-associated antigen-1(LFA-1), which is a cell-adhesion molecule that mediates important immunological events (1). BIRT 377 is also a leukocyte adhesion suppressor (1). Studies showed that BIRT 377 inhibits lymphocyte activity both in vitro and in vivo (2)References:(1) Aaron, J., et al.: Org. […]

Catalogue Number:B399700Chemical Name:BIRH 414Synonyms:11-Ethyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2′,3′-e][1,4]diazepin-6-one; BIRH 414 BS; USP Nevirapine Related Compound A; Nevirapine EP Impurity A; Nevirapine USP Related Compound AImpurity:Nevirapine EP Impurity A; Nevirapine USP Related Compound ACAS Number:133627-17-5Molecular Formula:C₁₄H₁₄N₄OMolecular Weight:254.29Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:BIRH 414 (Nevirapine EP Impurity A; Nevirapine USP Related Compound A) is an derivative of 1-[(2-Hydroxyethoxy)methyl]-6-(phenylthio)thymine, a highly potent inhibitor of […]

Catalogue Number:B399690Chemical Name:BIRG 616 BSSynonyms:5,11-Dihydro-4-methyl-6H-dipyrido[3,2-b:2′,3′-e][1,4]diazepin-6-one; Nevirapine EP Impurity BImpurity:Nevirapine EP Impurity BCAS Number:287980-84-1Molecular Formula:C₁₂H₁₀N₄OMolecular Weight:226.23Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Anti-virals/Anti-retrovirals;Applications:BIRG 616 BS (Nevirapine EP Impurity B) is a metabolite of Nevirapine (N391275), a potent and selective non-nucleoside inhibitor of HIV-1 Reverse Transcriptase used as an antiretroviral agent.References:Bernard, S., et al.: Bioorg. Med. […]

Catalogue Number:B399680Chemical Name:BIRG 613 BSSynonyms:5,11-Dihydro-4-methyl-11-propyl-6H-dipyrido[3,2-b:2′,3′-e][1,4]diazepin-6-one; Nevirapine EP Impurity CImpurity:Nevirapine EP Impurity CCAS Number:287980-85-2Molecular Formula:C₁₅H₁₆N₄OMolecular Weight:268.31Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Anti-virals/Anti-retrovirals;Applications:BIRG 613 BS (Nevirapine EP Impurity C) is an derivative of Nevirapine (N391275), a potent and selective non-nucleoside inhibitor of HIV-1 reverse transcriptase.References:Raghuram, P., et al.: J. Anal. Chem., 7, 825 (2008); Li, […]

Catalogue Number:B399610Chemical Name:(R,R)-2,2′-Bipyrrolidine L-Tartrate TrihydrateSynonyms:(2R,2’R)-2,2′-Bipyrrolidine (2R,3R)-2,3-Dihydroxybutanedioate;CAS Number:137037-21-9Molecular Formula:C₈H₁₆N₂(C₄H₆O₆)Molecular Weight:140.23(150.09)Category:Building Blocks; Miscellaneous;Applications:(R,R)-2,2′-Bipyrrolidine L-Tartrate Trihydrate is used in the preparation of bipyrrolidine-based family of manganese complexes that act as catalysts for the stereoselective epoxidation of alkenes.References:Garcia-Bosch, I., et al.: Adv. Synth. Catal., 354, 65 (2012);To ensure the stability of our products, the efficient express delivery service will […]

Catalogue Number:B399600Chemical Name:2,2′-BipyrroleSynonyms:2,2′-Bi-1H-pyrrole; 2,2′-Bispyrrole; NSC 90886;CAS Number:10087-64-6Molecular Formula:C₈H₈N₂Appearance:Pale Grey to Light Beige SolidMelting Point:>150°C (dec.)Molecular Weight:132.16Storage:4°CSolubility:Chloroform (Slightly, Heated), Methanol (Slightly)Category:Building Blocks; Catalyst;Applications:2,2′-Bipyrrole is used as a facilitator in the electrochemical polymerization of pyrrole and N-methylpyrrole.References:Wei, Y. et al.: Makromol. Chem. Rap. Comm., 12, 617 (1991); Tran, H. et al.: Macromol. Rap. Comm., 28, 2289 (2007);To […]

Catalogue Number:B399405Chemical Name:[1,4′-Bipiperidine]-4′-carboxamide DihydrochlorideSynonyms:[1,4′-Bipiperidine]-4′-carboxamide Hydrochloride (1:2);CAS Number:83732-56-3Alternate CAS #Free Form: 39633-82-4Molecular Formula:C₁₁H₂₁N₃O • 2HClAppearance:Yellow SolidMolecular Weight:211.30 + 72.92Solubility:Methanol/Water (1:1)Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:[1,4′-Bipiperidine]-4′-carboxamide Dihydrochloride is an intermediate used in the synthesis of Carpipramine Dihydrochloride (C184320), which is an typical antipsychotic used for the treatment of schizophrenia and anxiety. It is structurally related to Imipramine (I465980)References:Deniker P., […]

Catalogue Number:B399402Chemical Name:1,4′-Bipiperidinyl-4′-carboxamide-d10Synonyms:[1,4′-Bipiperidine]-4′-carboxamide-d10; 4-(1-Piperidinyl)-4-(aminocarbonyl)piperidine-d10; 4-Carbamoyl-4-(1-piperidinyl)piperidine-d10; [1,4′]Bipiperidinyl-4′-carboxylic Acid Amide-d10; NSC 76044-d10;CAS Number:1330277-11-6Alternate CAS #unlabelled: 39633-82-4Molecular Formula:C₁₁H₁₁D₁₀N₃OMolecular Weight:221.37Category:Building Blocks; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Labelled Piritramide intermediate.References:Mimura, M., et al.: Chem. Pharm. Bull., 41, 1971 (1993), Wahab, S., et al.: Int. J. Cancer Res., 4, 154 (2008),To ensure the stability of our products, the efficient express delivery […]