Chemical Name:4α,5-Dihydro Simvastatin-d6Synonyms:(1S,3S,4aR,7S,8S,8aS)-8-(2-((2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-1,2,3,4,4a,7,8,8a-octahydronaphthalen-1-yl 2,2-dimethylbutanoate-d6; Simvastatin impurity K-d6Molecular Formula:C₂₅H₃₄D₆O₅Molecular Weight:426.62Category:Research Tools;Applications:Isotope labelled 4α,5-Dihydro Simvastatin is an impurity in the synthesis of Simvastatin (S485000), a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor.References:Hoffman, W.F., […]
CEV (R)-S-Oxide
Chemical Name:CEV (R)-S-OxideCAS Number:124751-37-7Molecular Formula:C₁₀H₁₇NO₂SAppearance:White to Off-White SolidMelting Point:110-112°CMolecular Weight:215.31Storage:-20°CSolubility:Chloroform (Slightly), Methanol (Slightly)Category:Standards; Neurochemicals; Pharmaceutical/API Drug Impurities/Metabolites;Applications:CEV S-Oxide 2 is an impurity compound of Cevimeline (C283500). Cevimeline is a novel muscarinic M1 and M3 receptor agonist. Sialagogue.References:Masunaga, H., et al.: Eur. J. Pharmacol., 339, 1 (1997), Arisawa, H., et al.: Arzneim.-Forsch., 52, 14 (2002), Yasuda, […]
3-Chloro-1-(4-methylphenyl)propan-1-one
Chemical Name:3-Chloro-1-(4-methylphenyl)propan-1-oneSynonyms:3-Chloro-1-(4-methylphenyl)-1-propanone; 2-Chloroethyl 4-Methylphenyl Ketone; 3-Chloro-4′-methylpropiophenone; 4′-Methyl-3-chloropropiophenone; β-Chloroethyl p-tolyl Ketone;CAS Number:22422-21-5Molecular Formula:C₁₀H₁₁OClAppearance:White to Off-White SolidMelting Point:78 – 80°CMolecular Weight:182.64Storage:-20°CSolubility:Chloroform (Sparingly), Methanol (Slightly)Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:3-chloro-1-(4-methylphenyl)propan-1-one is a reagent used in the synthesis of Mannich base-type derivatives which can be used in the treatment of chagas disease.References:Martin-Escolano, R. et al.: J. Med. Chem., 61, 5843 (2018);To […]
Decyl b-D-maltopyranoside
Chemical Name:Decyl b-D-maltopyranosideSynonyms:Decyl 4-O-α-D-glucopyranosyl-β-D-glucopyranoside; 1-Decyl β-D-maltoside; 1-O-Decyl-β-D-maltoside; Decyl β-D-maltoside; Decyl β-Maltopyranoside; Decyl-β-maltoside; Decylmaltoside; n-Decyl β-D-maltoside; n-Decyl-β-D-maltopyranoside;CAS Number:82494-09-5Molecular Formula:C₂₂H₄₂O₁₁Appearance:White to Off-White SolidMelting Point:>95°C (dec.)Molecular Weight:482.56Storage:-20°CSolubility:Methanol (Slightly), Water (Slightly)Category:Building Blocks; Carbohydrates;Applications:Decyl b-D-maltopyranosideTo ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the […]
N-Desacetyl-N-formyl Apremilast
Chemical Name:N-Desacetyl-N-formyl ApremilastSynonyms:N-[2-[(1S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-formamide;CAS Number:2077897-94-8Molecular Formula:C₂₁H₂₂N₂O₇SAppearance:White to Off-White SolidMelting Point:147 – 151°CMolecular Weight:446.47Storage:-20°CSolubility:Chloroform (Sparingly), Methanol (Slightly)Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:N-Desacetyl-N-formyl Apremilast is the impurity of Apremilast (A729700), which is an oral phosphodiesterase 4 inhibitor used in the treatment of psoriatic arthritis.References:Gan, E., et al.: BioDrugs, 27, 359 (2013); Pathan, E., et al.: Annal. Rheum. DIs., 72, 1475 […]
rac Desisopropyl Tolterodine
Chemical Name:rac Desisopropyl TolterodineSynonyms:4-Methyl-2-[3-[(1-methylethyl)amino]-1-phenylpropyl]phenol; N-Isopropyl-3-(2-hydroxy-5-methylphenyl)-3-phenylpropylamine;CAS Number:480432-14-2Molecular Formula:C₁₉H₂₅NOAppearance:Pale Beige to Light Brown SolidMelting Point:95-97°CMolecular Weight:283.41Storage:4°CSolubility:Chloroform (Slightly), Methanol (Slightly)Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:A metabolite of Tolterodine (T535800) used in the treatment of smooth muscle hyperactivity.References:Nilvebrant, L., et al.: Life Sci., 60, 1129 (1997); Nilvebrant, L., et al.: Eur. J. Pharmacol., 327, 195 (1997);To ensure the stability of our […]
6,7-Dihydrothieno[3,2-c]pyridine
Chemical Name:6,7-Dihydrothieno[3,2-c]pyridineSynonyms:6,7-Dihydro[3,2-c]thienopyridine; Clopidogrel Related CompoundCAS Number:107112-93-6Alternate CAS #:107112-91-4 (HCl salt)Molecular Formula:C₇H₇NSAppearance:Pale Yellow to Dark Brown SolidMolecular Weight:137.2Storage:4°CSolubility:Dichloromethane (Slightly, Heated), DMSO (Slightly, Heated), Methanol (Slightly)Category:Building Blocks; Miscellaneous;Applications:Used in the synthesis of thieno[3,2-a]quinolizidines and attempts to prepare Papaverine analogs.References:Schmid, H., et al.: Helv. Chim. Acta, 32, 960 (1949),To ensure the stability of our products, the efficient express […]
4-(Ethylenediol-methoxy)-9H-carbazole
Chemical Name:4-(Ethylenediol-methoxy)-9H-carbazoleMolecular Formula:C₁₅H₁₅NO₂Appearance:Off-White SolidMelting Point:82-84°CMolecular Weight:241.29Storage:4°CSolubility:DMSO (Slightly), Methanol (Slightly)Category:Building Blocks; Miscellaneous;Applications:4-(Ethylenediol-methoxy)-9H-carbazole is derived from 2-Bromoethyl Methyl Ether (B685140), which is used as reactant for the preparation of alkyl ethers of b-alkylcholine salts.References:Major, R.T., Cline, J.K.: J. Am. Chem. Soc., 55, 2504 (1933)To ensure the stability of our products, the efficient express delivery service will be […]
4H-Furo[2,3-c]pyranyl Mupirocin Sodium Impurity
Chemical Name:4H-Furo[2,3-c]pyranyl Mupirocin Sodium ImpuritySynonyms:[2R-[2α(1S*,2S*,3S*),3aβ,6α(E),7β,7aα]]-9-[[4-[2-(1,3-Dihydroxy-2-methylbutyl)hexahydro-7-hydroxy-4H-furo[3,2-c]pyran-6-yl]-3-methyl-1-oxo-2-butenyl]oxy]nonanoic Acid Monosodium Salt;ImpurityMupirocin EP Impurity DCAS Number:116182-43-5Alternate CAS #:Free cmpd: 71087-97-3Molecular Formula:C₂₆H₄₃NaO₉Appearance:White to Off-White SolidMelting Point:151-154°CMolecular Weight:522.6Storage:-20°C, HygroscopicSolubility:Methanol (Slightly), Water (Slightly)StabilityHygroscopicCategory:Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Mupirocin (M794000) impurity. (Mupirocin EP Impurity D) The rearrangement isomer of Mupirocin is prepared using an enzyme-catalyzed, selective deesterification.References:Sime, J.T., et al.: Tetrahedron Lett.,В 28,В 5169 (1987),To […]
Gemcitabine Diphosphate Choline
Chemical Name:Gemcitabine Diphosphate CholineSynonyms:Gemcitabine 5’-Diphosphate Choline;CAS Number:1643126-46-8Molecular Formula:C₁₄H₂₄F₂N₄O₁₀P₂Appearance:White to Off-White SolidMelting Point:>226ºC (dec.)Molecular Weight:508.31Storage:-20°C, HygroscopicSolubility:Water (Slightly)Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Gemcitabine (G305000) derivative. An antineoplastic agent.References:Kennedy., E.P., et al.: J. Biol. Chem., 222, 193 (1956),To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be […]