Chemical Name:(4S)-4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic Acid-13C2,15NSynonyms:D-Luciferin-13C2,15N; Firefly-13C2,15NAlternate CAS #:Unlabelled: 2591-17-5Molecular Formula:C₉¹³C₂H₈N¹⁵NO₃S₂Molecular Weight:283.3Category:Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors;Applications:(4S)-4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic Acid-13C2,15N is labelled (4S)-4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic Acid (K salt, D449725) which is a class of light-emitting heterocyclic compounds found in organisms that cause bioluminescence, such as firefly. It produces light upon oxidative decarboxylation by luciferase in the presence of ATP.References:Hastings, J., […]

Chemical Name:3,8-DichloroacenaphtheneSynonyms:3,8-Dichloro-1,2-dihydroacenaphthyleneMolecular Formula:C₁₂H₈Cl₂Molecular Weight:223.1Category:Standards; Environmental Standards, Mutagens and Metabolites;Applications:3,8-Dichloroacenaphthene is a chlorinated derivative of Acenaphthene (D448330); a polycyclic hydrocarbon that has potential to act as polyploidizing agents in plants.References:Campbell, K., et al.: J. Org. Chem., 16, 1712 (1951); Reisen, F. & Arey J.: Env. Sci. Tech., 36, 4302 (2002)To ensure the stability of our products, […]

Chemical Name:4α,5-Dihydro Simvastatin-d6Synonyms:(1S,3S,4aR,7S,8S,8aS)-8-(2-((2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-1,2,3,4,4a,7,8,8a-octahydronaphthalen-1-yl 2,2-dimethylbutanoate-d6; Simvastatin impurity K-d6Molecular Formula:C₂₅H₃₄D₆O₅Molecular Weight:426.62Category:Research Tools;Applications:Isotope labelled 4α,5-Dihydro Simvastatin is an impurity in the synthesis of Simvastatin (S485000), a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor.References:Hoffman, W.F., […]

Chemical Name:3,5-Dichloro-N-[[(1α,5α,6-exo,6α)-3-(3,3-dimethylbutyl)-3-azabicyclo[3.1.0]hex-6-yl]methyl]-benzamide-d9Synonyms:3,5-dichloro-N-[[(1S,5R)-3-(3,3-dimethylbutyl)-3-azabicyclo-[3.1.0]hexan-6-yl]methyl]benzamide-d9; ML218-d9; CID-45115620-d9;Alternate CAS #:Unlabelled: 1346233-68-8Molecular Formula:C₁₉H₁₇D₉Cl₂N₂OMolecular Weight:378.38Category:Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Isotope labelled analogue to the compound referred to as ML218 (D434077), a centrally active calcium channel inhibitor with potential applications to treatment of pain, epilepsy and neurological disorders through further study.References:Xiang, Z. et al.: ACS Chem. Neurosci., […]

Chemical Name:Dihydrodiol Ibrutinib-d5Synonyms:1-[3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-2,3-dihydroxypropan-1-one-d5; 1-[3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2,3-dihydroxy-1-propanone-d5Alternate CAS #:1226872-27-0 unlabelledMolecular Formula:C₂₅H₂₁D₅N₆O₄Molecular Weight:479.54Category:Building Blocks; Isotopic Labeled Analogues;Applications:Dihydrodiol Ibrutinib-d5 is the isotopic metabolite of Ibrutinib (I124970). Ibrutinib is a highly selective Bruton’s tyrosine kinase (Btk) irreversible inhibitor.References:MacGlashan, D., et. al.: Int. Immunol., 11, 475 (2011)To ensure the stability of our products, the efficient express delivery service will be used. We […]

Chemical Name:17,21-Dihydroxy-16β-methylpregna-1,4-diene-3,20-dione DipropionateSynonyms:2-oxo-2-((8R,10R,13S,14S,16S,17R)-10,13,16-Trimethyl-3-oxo-17-(propionyloxy)-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)ethyl Propionate; 9-Deschloro-11-deshydroxy Beclomethasone 17,21-DipropionateImpurityBeclomethasone Dipropionate EP Impurity QMolecular Formula:C₂₈H₃₈O₆Molecular Weight:470.6Category:Research Tools;Applications:17,21-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione Dipropionate is a corticoid with the potential for ant-iinflammatory activity. Impurity of Beclomethasone (B131000), a glucocorticoid. Used in chronic asthma and allergic rhinitis. Antiallergic, antiasthmatic (inhalant). Anti-inflammatory (topical).References:Collins, E. et al.: Proc. Int. Congr. Horm. Steroids, 2nd, 530 (1967); Malfitan, V.A., […]

Chemical Name:Dichloroisoeverninic Acid-D6Synonyms:3,5-Dichloro-4-hydroxy-2-methoxy-6-methylbenzoic Acid-D6Alternate CAS #:4101-80-8Molecular Formula:C₉H₂D₆Cl₂O₄Molecular Weight:257.1Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Dichloroisoeverninic Acid-D6 is a deuterium labelled Dichloroisoeverninic Acid(D437986), which is a metabolite of the orthosomycin antibiotic avilamycin.References:Ho, C., et al.: Anal. Bioanal. Chem., 405, 8633 (2013); Magnussen, J. D., et al.: J. Agric. Food Chem., 39, 306 (1991)To ensure the stability of […]

Chemical Name:1,7-Dichloroisoquinoline-d3Synonyms:1,7-Dichloroisoquinoline-5,6,8-d3;Alternate CAS #:70810-24-1Molecular Formula:C₉H₂D₃Cl₂NMolecular Weight:201.06Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;Applications:1,7-Dichloroisoquinoline-d3 is the labeled analogue of 1,7-Dichloroisoquinoline (D438548), used in preparation of 1H-1,2,3-Triazole-5-carboxylic Acid derivatives as Glycolate Oxidase inhibitors for treatment of Hyperoxaluria and related diseases.References:Bai, X., et al.: PCT Int. Appl., (2020);To ensure the stability of our products, the efficient express delivery service […]

Chemical Name:Di(N-desethyl) Amiodarone-d4 HydrochlorideSynonyms:[4-(2-Aminoethoxy)-3,5-diiodophenyl](2-butyl-3-benzofuranyl)methanone-d4 Hydrochloride;Alternate CAS #:757220-04-5Molecular Formula:C₂₁H₂₁D₄I₂NO₃ • HClMolecular Weight:597.26 + 36.46Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Di(N-desethyl) Amiodarone-d4 Hydrochloride is a labeled analogue of Di(N-desethyl) Amiodarone Hydrochloride (D440750), which is a novel metabolite of Amiodarone in plasma. Amiodarone Didesethyl ImpurityReferences:Elvin, A., et al.: J. Pharm. Sci., 69, 47 (1980), Ou, C., et al.: […]

Chemical Name:Di(N-desethyl) Amiodarone-d3 HydrochlorideSynonyms:[4-(2-Aminoethoxy)-3,5-diiodophenyl](2-butyl-3-benzofuranyl)methanone-d3 Hydrochloride;Alternate CAS #:757220-04-5Molecular Formula:C₂₁H₂₁D₃I₂NO₃ • HClMolecular Weight:595.25 + 36.46Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Di(N-desethyl) Amiodarone-d3 Hydrochloride is a labeled analogue of Di(N-desethyl) Amiodarone Hydrochloride (D440750), which is a novel metabolite of Amiodarone in plasma. Amiodarone Didesethyl ImpurityReferences:Elvin, A., et al.: J. Pharm. Sci., 69, 47 (1980), Ou, C., et al.: […]