β-Dihydrotetrabenazine-D7

Chemical Name:β-Dihydrotetrabenazine-D7Synonyms:(2S,3R,11bR)-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-ol-D7Alternate CAS #:924854-60-4Molecular Formula:C₁₉H₂₂D₇NO₃Molecular Weight:326.48Applications:β-Dihydrotetrabenazine-D7 is an isotopic labeled analogue of (+)-β-Dihydrotetrabenazine(D453610). (+)-β-Dihydrotetrabenazine is a potent inhibitor of vascular monoamine transporter 2 (VMAT2) and an agent of significant interest for therapeutic and molecular imaging applications.References:Yao, Z., et al.: Eur. J. Med. Chem., 46, 1841 (2011); Rishel, M.J., et al.: J. Org. Chem., 74, 4001 […]

c-Di[2’FdGMP(S)]

Chemical Name:c-Di[2’FdGMP(S)]Synonyms:9,9′-((2R,3R,3aR,7aS,9S,10R,10aR,14aR)-3,10-Difluoro-5,12-dihydroxy-5,12-dioxidodecahydrodifuro[3,2-d:3′,2′-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl)bis(2-amino-3H-purin-6(9H)-one);Molecular Formula:C20H22F2N10O10P2S2Molecular Weight:726.52Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:c-Di[2’FdGMP(S)] is a potential riboswitch class I agent used in the regulation of bacterial physiology.To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against […]

17Alpha,21-Dihydroxy-16Alpha-methyl-1,4-pregnadiene-3,20-dione

Chemical Name:17Alpha,21-Dihydroxy-16Alpha-methyl-1,4-pregnadiene-3,20-dioneSynonyms:(16α)-17,21-Dihydroxy-16-methylpregna-1,4-diene-3,20-dione; 17,21-Dihydroxy-16α-methyl-pregna-1,4-diene-3,20-dione;CAS Number:19784-87-3Molecular Formula:C₂₂H₃₀O₄Molecular Weight:358.47Category:Building Blocks;Applications:17α,21-Dihydroxy-16α-methyl-1,4-pregnadiene-3,20-dione is a reagent used in the synthesis of dexamethasone.References:Ma, R., et al.: Zhongguo Yiyao Gongye Zazhi, 20, 1-5 (1989)To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of […]

3,3′-(Isopropylazanediyl)bis(1-(4-((2-isopropoxyethoxy)methyl)phenoxy)propan-2-ol)

Chemical Name:3,3′-(Isopropylazanediyl)bis(1-(4-((2-isopropoxyethoxy)methyl)phenoxy)propan-2-ol)Synonyms:Bisoprolol Dimer;Molecular Formula:C₃₃H₅₃NO₈Appearance:Colourless OilMolecular Weight:591.78Storage:4°CSolubility:Chloroform (Slightly), Methanol (Slightly)Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:3,3′-(Isopropylazanediyl)bis(1-(4-((2-isopropoxyethoxy)methyl)phenoxy)propan-2-ol), is an impurtiy of Bisoprolol (B510500), a selective b-adrenergic blocker. Used as an antihypertensive.References:Tattersfield, A.E., et al.: Brit. J. Clin. Pharmacol., 18, 343 (1984), Kohli, R.S., et al.: Eur. Heart J., 6, 845 (1985), Zachariah, P.K., et al.: Clin. Ther., 15, 779 (1993),To […]

Dihydro Folic Acid-D4 (Technical Grade)

Chemical Name:Dihydro Folic Acid-D4 (Technical Grade)Synonyms:N-[4-[[(2-Amino-3,4,7,8-tetrahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic Acid-D4; N-[p-[[(2-Amino-7,8-dihydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-L- Ggutamic Acid-D4; N-[4-[[(2-Amino-1,4,7,8-tetrahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic Acid-D4; 7,8-Dihydro-L-folic Acid-D4; 7,8-Dihydrofolic Acid-D4; Dihydrofolic Acid-D4;Alternate CAS #:Unlabelled: 4033-27-6Molecular Formula:C₁₉H₁₇D₄N₇O₆Molecular Weight:447.44Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Dihydro Folic Acid-D4 is an isotopic analog of Dihydro Folic Acid (D449700), an intermediate in mammalian conversion of dietary folic acid to tetrahydrofolate by dihydrofolate reductase (DHFR).References:Andres, […]

Itaconic Acid-13C5,d4

Chemical Name:Itaconic Acid-13C5,d4Synonyms:2-Methylenebutanedioic Acid-13C5,d4; 2-Methylenesuccinic Acid-13C5,d4; 2-Propene-1,2-dicarboxylic Acid-13C5,d4; 4-Hydroxy-2-methylene-4-oxobutanoic Acid-13C5,d4; Methylenebutanedioic Acid-13C5,d4; Methylenesuccinic Acid-13C5,d4; NSC 3357-13C5,d4; Propylenedicarboxylic Acid-13C5,d4;Alternate CAS #:unlabelled: 97-65-4Molecular Formula:¹³C₅H₂D₄O₄Appearance:Off-White to Pale Yellow SolidMolecular Weight:139.09Storage:-20°C, Inert atmosphere, Light sensitiveSolubility:DMSO (Slightly), Methanol (Slightly)StabilityLight Sensitive, Temperature sensitiveCategory:Building Blocks; Monomers; Isotopic Labeled Analogues;Applications:Labelled analogue of Itaconic Acid, a fermentation product of carbohydrates such as glucose using […]

(4S)-4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic Acid-13C2,15N

Chemical Name:(4S)-4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic Acid-13C2,15NSynonyms:D-Luciferin-13C2,15N; Firefly-13C2,15NAlternate CAS #:Unlabelled: 2591-17-5Molecular Formula:C₉¹³C₂H₈N¹⁵NO₃S₂Molecular Weight:283.3Category:Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors;Applications:(4S)-4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic Acid-13C2,15N is labelled (4S)-4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic Acid (K salt, D449725) which is a class of light-emitting heterocyclic compounds found in organisms that cause bioluminescence, such as firefly. It produces light upon oxidative decarboxylation by luciferase in the presence of ATP.References:Hastings, J., […]

3,8-Dichloroacenaphthene

Chemical Name:3,8-DichloroacenaphtheneSynonyms:3,8-Dichloro-1,2-dihydroacenaphthyleneMolecular Formula:C₁₂H₈Cl₂Molecular Weight:223.1Category:Standards; Environmental Standards, Mutagens and Metabolites;Applications:3,8-Dichloroacenaphthene is a chlorinated derivative of Acenaphthene (D448330); a polycyclic hydrocarbon that has potential to act as polyploidizing agents in plants.References:Campbell, K., et al.: J. Org. Chem., 16, 1712 (1951); Reisen, F. & Arey J.: Env. Sci. Tech., 36, 4302 (2002)To ensure the stability of our products, […]

4α,5-Dihydro Simvastatin-d6

Chemical Name:4α,5-Dihydro Simvastatin-d6Synonyms:(1S,3S,4aR,7S,8S,8aS)-8-(2-((2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-1,2,3,4,4a,7,8,8a-octahydronaphthalen-1-yl 2,2-dimethylbutanoate-d6; Simvastatin impurity K-d6Molecular Formula:C₂₅H₃₄D₆O₅Molecular Weight:426.62Category:Research Tools;Applications:Isotope labelled 4α,5-Dihydro Simvastatin is an impurity in the synthesis of Simvastatin (S485000), a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor.References:Hoffman, W.F., […]

3,5-Dichloro-N-[[(1α,5α,6-exo,6α)-3-(3,3-dimethylbutyl)-3-azabicyclo[3.1.0]hex-6-yl]methyl]-benzamide-d9

Chemical Name:3,5-Dichloro-N-[[(1α,5α,6-exo,6α)-3-(3,3-dimethylbutyl)-3-azabicyclo[3.1.0]hex-6-yl]methyl]-benzamide-d9Synonyms:3,5-dichloro-N-[[(1S,5R)-3-(3,3-dimethylbutyl)-3-azabicyclo-[3.1.0]hexan-6-yl]methyl]benzamide-d9; ML218-d9; CID-45115620-d9;Alternate CAS #:Unlabelled: 1346233-68-8Molecular Formula:C₁₉H₁₇D₉Cl₂N₂OMolecular Weight:378.38Category:Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Isotope labelled analogue to the compound referred to as ML218 (D434077), a centrally active calcium channel inhibitor with potential applications to treatment of pain, epilepsy and neurological disorders through further study.References:Xiang, Z. et al.: ACS Chem. Neurosci., […]

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