Chemical Name:N-[(1R,2S)-2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1-pyrrolidinylmethyl)ethyl]-octanamideCAS Number:1092472-66-6Molecular Formula:C₂₃H₃₆N₂O₄Molecular Weight:404.54Category:Building Blocks; Miscellaneous;Applications:N-[(1R,2S)-2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1-pyrrolidinylmethyl)ethyl]-octanamide is derived from N-Carboxyl-L-serine N-Benzyl Ester (C182415), which is a building block in peptide synthesis.References:Pansare, S. V.; Org. Synth. 70, 10(1992)To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with […]

Chemical Name:(αR)-5,6-Dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamineCAS Number:802918-36-1Molecular Formula:C₂₂H₂₄F₃NMolecular Weight:359.43Category:Building Blocks;Applications:(αR)-5,6-Dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine is synthetically prepared though a double bond migration in Heck reaction during the preparation of cinacalcet congeners. This enantiomerically pure material is seperated from its counter part, (αR)-7,8-Dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine (D455330) using HPLC.References:Wang, X., et al.: Tetrahedron Lett., 45, 8355 (2004)To ensure the stability of our products, the efficient express delivery […]

Chemical Name:(1R,2S)-rel-2-(2,3-Dihydro-4-benzofuranyl)-cyclopropanemethanamineSynonyms:(1R,​2S)​-​rel-2-​(2,​3-​Dihydro-​4-​benzofuranyl)​-​, Cyclopropanemethanam​ine,CAS Number:251562-77-3Molecular Formula:C₁₂H₁₅NOMolecular Weight:189.25Category:Building Blocks; Miscellaneous;Applications:(1R,2S)-rel-2-(2,3-Dihydro-4-benzofuranyl)-cyclopropanemethanamine is used in the preparation of pharmaceuticals as melatonin receptor agonists.References:Chen, J. et al.: PCT Int. Appl. (1999), WO 9962515 A1 19991209To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the […]

Chemical Name:(2S,2’S)-3,3′-(((6,6′-Dihydroxy-5,5′-diiodo-[1,1′-biphenyl]-3,3′-diyl)bis(oxy))bis(3,5-diiodo-4,1-phenylene))bis(2-aminopropanoic acid)CAS Number:2088032-54-4Alternate CAS #:Parent compound: 51-48-9Molecular Formula:C₃₀H₂₂I₆N₂O₈Molecular Weight:1299.93Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:(2S,2’S)-3,3′-(((6,6′-Dihydroxy-5,5′-diiodo-[1,1′-biphenyl]-3,3′-diyl)bis(oxy))bis(3,5-diiodo-4,1-phenylene))bis(2-aminopropanoic acid) is a Levothyroxine impurity of Thyroxine (T425600), which is one of the thyroid hormones involved in the maintenance of metabolic homeostasis. Thyroxine is deiodinated in peripheral tissues to the active metabolite, liothyronine, which has been used to treat hyperlipidemia.References:Post, A., et […]

Chemical Name:Dihydro Idebenone 4-Sulfate 1-Glucuronide Dipotassium SaltMolecular Formula:C₂₅H₃₈K₂O₁₄SMolecular Weight:672.82Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Dihydro Idebenone 4-Sulfate 1-Glucuronide Dipotassium Salt is derived from Idebenone (I170050), which is a ubiquinone derivative with protective effects against cerebral ischemia. This compound has neuroprotective and nootropic properties.References:Barkworth, M.F., et al.: Arzneim.-Forsch., 35, 1704 (1985), Kobayashi, T., et al.: J. Pharmacobio-Dyn., 8, 448 […]

Chemical Name:(10β, 8β)-Dihydroxy NaltrexoneSynonyms:(4R,4aS,5S,7aR,12bS,13R)-3-(Cyclopropylmethyl)-4a,5,9,13-tetrahydroxy-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-oneMolecular Formula:C₂₀H₂₃NO₆Molecular Weight:373.4Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:(10β, 8β)-Dihydroxy Naltrexone is a derivative of Naltrexone (N285750), a nonselective opioid receptor antagonist; congener of Naloxone.References:Maickel, R.P., et al.: Ann. N.Y. Acad. Sci., 281, 321 (1976), Gritz, E.R., et al.: Clin. Pharmacol. Ther. 19, 773 (1976), Gonzales, J.P., et al.: Drugs, 35, 192 (1988), Berg, B.J., […]

Chemical Name:7β,25-DihydroxycholesterolSynonyms:3β,7β,25-Trihydroxycholest-5-ene; (3β,7β)-Cholest-5-ene-3,7,25-triol;CAS Number:64907-21-7Molecular Formula:C₂₇H₄₆O₃Molecular Weight:418.65Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Steroids;Applications:7β,25-Dihydroxycholesterol is a potent and selective agonist of EB12. This compound can be used as a drug delivery system containing oxidized cholesterol.References:Hannedouche, Sebastien., Nature (London, United Kingdom), 475, 524-527, (2011); Dahlman, J., et.al., PCT Int. Appl., 63, (2020);To ensure the stability of our products, the efficient […]

Chemical Name:erythro-β,3-Dihydroxy-D-tyrosineSynonyms:(-)-erythro-3,4-Dihydroxyphenylserine; D-erythro-3,4-DihydroxyphenylserineCAS Number:51829-98-2Molecular Formula:C₉H₁₁NO₅Molecular Weight:213.19Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:erythro-β,3-Dihydroxy-D-tyrosine as an adrenergic pro-drug. Bioactivation of erythro-β,3-Dihydroxy-D-tyrosine to the potent pharmacological agent, noradrenalone (arterenone), via sequential stereoselective action by two target enzymes – dopamine β-monooxygenase (DBM) and L-arom. amino acid decarboxylase (AADC) – acting in tandem.References:Debnath, J., et al.: Biochem. Biophys. Res. Commun., 189, 33-9 (1992)To […]

Chemical Name:erythro-β,3-Dihydroxy-L-tyrosineSynonyms:Serine, 3-(3,4-dihydroxyphenyl)-, L-erythro- (8CI); (βS)-β,3-Dihydroxy-L-tyrosine; (+)-erythro-3,4-Dihydroxyphenylserine; L-erythro-3,4-DihydroxyphenylserineL-erythro-3-(3,4-Dihydroxyphenyl)serine; erythro-Dopaserine; L-Tyrosine, β,3-dihydroxy-, (βS)-;CAS Number:34047-62-6Molecular Formula:C₉H₁₁NO₅Molecular Weight:213.19Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:erythro-β,3-Dihydroxy-L-tyrosine administered to rats inhibited the methamphetamins-induced locomotor activity and decreased the brain dopamine content.References:Harada, H., et al.: Yakubutsu Seishin Kodo., 11, 403 (1991)To ensure the stability of our products, the efficient express delivery service will be used. […]

Chemical Name:N-[(3β,7α,12α)-7,12-Dihydroxy-24-oxo-3-(sulfooxy)chol-5-en-24-yl]glycine Disodium SaltCAS Number:1638974-22-7Alternate CAS #:Free Base: 1427772-30-2Molecular Formula:C₂₆H₃₉NNa₂O₉SMolecular Weight:587.63Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Steroids;Applications:N-[(3β,7α,12α)-7,12-Dihydroxy-24-oxo-3-(sulfooxy)chol-5-en-24-yl]glycine Disodium Salt is derived from Cholic Acid (C432600), which is produced by, and isolated from liver cells.References:Nomoto, M., et al.: Biol. Pharm. Bull., 32, 172 (2009), Simonsen, H., et al.: J. Agric. Food Chem., 57, 2056 (2009), Miyata, M., et […]