Chemical Name:Edoxaban Cyclohexyl Methyl EsterSynonyms:Edoxaban Cyclohexyl Methyl Ester Impurity; Methyl (1S,3R,4S)-4-(2-((5-Chloropyridin-2-yl)amino)-2-oxoacetamido)-3-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexane-1-carboxylate;Molecular Formula:C₂₃H₂₇ClN₆O₅SMolecular Weight:535.02Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Edoxaban Cyclohexyl Methyl Ester is an impurity of Edoxaban(E555520). Edoxaban is an anticoagulant drug which acts as a direct factor Xa inhibitor.References:Ruff, C., et al.: Am. Heart J., 160, 635 (2010); Ogata, K., et al.: J. Clin. Pharm., 50, 73 […]
N2-[(2R)-4-[(1,1-Dimethylethoxy)amino]-2-(2-naphthalenylmethyl)-1,4-dioxobutyl]-N5-[[[2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl]sulfonyl]amino]iminoethyl-L-ornithine
Chemical Name:N2-[(2R)-4-[(1,1-Dimethylethoxy)amino]-2-(2-naphthalenylmethyl)-1,4-dioxobutyl]-N5-[[[2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl]sulfonyl]amino]iminoethyl-L-ornithineCAS Number:1093740-20-5Molecular Formula:C₃₈H₅₁N₅O₈SMolecular Weight:737.91Category:Research Tools;Applications:Intermediate in the synthesis of substrate-selective peptide hydroxamate inhibitor of insulin-degrading enzyme, N2-[(2R)-4-(Hydroxyamino)-2-(2-naphthalenylmethyl)-1,4-dioxobutyl]-L-arginyl-L-tryptophyl-L-α-glutamine (H828110).References:Abdul-Hay, S.O., et al.: J. Med. Chem., 56, 2246 (2013);To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with […]
2,2-Dimethyl Gibberellin A4
Chemical Name:2,2-Dimethyl Gibberellin A4Synonyms:(1α,2β,4aα,4bβ,10β)-2,4a-Dihydroxy-1,3,3-trimethyl-8-methylenegibbane-1,10-dicarboxylic Acid 1,4a-LactoneCAS Number:79035-06-6Molecular Formula:C₂₁H₂₈O₅Molecular Weight:360.44Category:Standards; Environmental Standards, Mutagens and Metabolites;Applications:2,2-Dimethyl Gibberellin A4 is a derivative of Gibberellic Acid (G377450), a hormone that is found in plants which promotes the growth and elongation of cells. Gibberellic acid acts as a plant growth regulator on account of its physiological and morphological effects in […]
1,7-Dimethyl-1H-imidazo[4,5-g]quinoxalin-2-amine
Chemical Name:1,7-Dimethyl-1H-imidazo[4,5-g]quinoxalin-2-amineSynonyms:2-Amino-1,7-dimethyl-1H-imidazo[4,5-g]quinoxaline; 7-MeIgQx;CAS Number:934333-16-1Molecular Formula:C₁₁H₁₁N₅Molecular Weight:213.24Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Environmental Standards, Mutagens and Metabolites;Applications:An abundant mutagenic heterocyclic aromatic amine (HAA) formed in cooked beef and other meats.References:Turesky, R.J. et al.: Chem. Res. Toxicol., 20, 520 (2007); Ni, W. et al.: J. Agric. Food Chem., 56, 68 (2008);To ensure the stability of our products, the efficient […]
6(7)-Dehydro Fulvestrant-9-sulfone
Chemical Name:6(7)-Dehydro Fulvestrant-9-sulfoneSynonyms:7alpha-[9-[(4,4,5,5,5-Pentafluoropentyl)sulfonyl]nonyl]estra-1,3,5(10),6(7)-tetraene-3,17beta-diolMolecular Formula:C₃₂H₄₅F₅O₄SMolecular Weight:620.75Category:Building Blocks;Applications:6(7)-Dehydro Fulvestrant-9-sulfone is a steroid and derivative compound of Fulvestrant (F862500). Fulvestrant is a novel steroidal estrogen antagonist reported to lack any partial agonist activity. Antineoplastic (hormonal).References:Wakeling, A.E., et al.: Cancer Res., 51, 3867 (1991), Howell, A., et al.: Br. J. Cancer, 74, 300 (1996), Robertson, J.F., et al.: Cancer […]
5,5-Dimethyl-3-(2-((7-methyl-2H-spiro[benzofuran-3,1′-cyclopropan]-4-yl)oxy)pyrimidin-5-yl)imidazolidine-2,4-dione
Chemical Name:5,5-Dimethyl-3-(2-((7-methyl-2H-spiro[benzofuran-3,1′-cyclopropan]-4-yl)oxy)pyrimidin-5-yl)imidazolidine-2,4-dioneSynonyms:Kv3 Modulator 1CAS Number:1380696-64-9Molecular Formula:C₂₀H₂₀N₄O₄Molecular Weight:380.4Category:Research Tools; Molecular Biology; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:5,5-Dimethyl-3-(2-((7-methyl-2H-spiro[benzofuran-3,1′-cyclopropan]-4-yl)oxy)pyrimidin-5-yl)imidazolidine-2,4-dione is a hydantoin derivative that functions as a Kv3 inhibitor for the treatment of pain and acute noise-induced hearing loss.References:Large, C.: From PCT Int. Appl. (2013), WO 2013175211 A1 20131128, Large, C., et al.: From PCT Int. Appl. (2017), WO 2017098254 A1 20170615To ensure the stability of our […]
1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine 6,8-Difluoro-7-hydroxycoumarin-3-carboxamide
Chemical Name:1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine 6,8-Difluoro-7-hydroxycoumarin-3-carboxamideMolecular Formula:C₄₃H₆₈F₂NO₁₂PMolecular Weight:859.97Category:Research Tools;Applications:1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine 6,8-Difluoro-7-hydroxycoumarin-3-carboxamide is Tetradecanoic Acid (1R)-1-[[[(2-Aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl Ester (T291535) conjugated to the fluorochrome “Pacific Blue”.To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The […]
m,p-O-Dimethyl-L-threo-droxidopa-d6
Chemical Name:m,p-O-Dimethyl-L-threo-droxidopa-d6Synonyms:Methoxylated dihiydroxyphenylserine-d6Alternate CAS #:Unlabeled: 146565-98-2Molecular Formula:C₁₁H₉D₆NO₅Molecular Weight:247.28Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:m,p-O-Dimethyl-L-threo-droxidopa-d6 is the labeled version of m,p-O-Dimethyl-L-threo-droxidopa (D480813), which is a useful intermediate for the manufacturing of pharmaceuticals.To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with […]
1,3-Bis(tertButyldimethylsilyl)-25-Tetrahydropyranyl Paricalcitol
Chemical Name:1,3-Bis(tertButyldimethylsilyl)-25-Tetrahydropyranyl ParicalcitolMolecular Formula:C₄₄H₈₀O₄Si₂Molecular Weight:729.27Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:(((1R,3R)-5-((E)-2-(1-((E)-5,6-Dimethyl-6-((tetrahydro-2H-pyran-2-yl)oxy)hept-3-en-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)cyclohexane-1,3-diyl)bis(oxy))bis(tert-butyldimethylsilane) is an intermediate in the synthesis of 24R-Paricalcitol (P195365), which is a useful intermediate that is structurally related to Paricalcitol (P195300), a synthetic analog of Vitamin D that is classified an an antihyperparathyroid.References:Sidek, H., et al.: Biochim. Biophys. Acta, 801, 26 (1984), Ciftci, M., et al.: J. […]
Dibenzylcyclooctyne-PEG4-ATTO-425
Chemical Name:Dibenzylcyclooctyne-PEG4-ATTO-425Synonyms:ATTO425; DBCO-PEG4-ATTO-425Molecular Formula:C₅₁H₆₂N₄O₁₁Molecular Weight:907.06Category:Research Tools; Molecular Biology; Fluorescent Reagents;Applications:Dibenzylcyclooctyne-PEG4-ATTO-425, is a Fluorescent dye. (Abs/Em = 436/484 nm)References:Liu et al. J Bacteriol 198:3045. (2016);To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to […]