Dapagliflozin-6-13C

Chemical Name:Dapagliflozin-6-13CSynonyms:(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)6-13c-phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triolMolecular Formula:C₁₅¹³C₆H₂₅ClO₆Molecular Weight:414.83Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Dapagliflozin-6-13C is an impurity and labelled form of Dapagliflozin (D185370) A sodium-glucose transporter 2 inhibitor.References:Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011)To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in […]

2,5-Difluorophenyl Evogliptin Tartrate

Chemical Name:2,5-Difluorophenyl Evogliptin TartrateSynonyms:(R)-4-{(R)-3-amino-4-(2,5-difluorophenyl)butanoyl}-3-(tbutoxymethyl)piperazin-2-one L-tartrateMolecular Formula:C₁₉H₂₇F₂N₃O₃ • (C₄H₆O₆)Molecular Weight:383.43 + (150.09)Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:2,5-Difluorophenyl Evogliptin Tartrate is an impurity of Evogliptin Tartrate (E945915) which is a useful intermediate used in the preparation of dipeptidyl peptidase-IV inhibitors and derivatives for the treatment of type 2 diabetes.References:Kim, J., et al.: Bioorg. Med. Chem. Lett., 21, 3809 (2011); […]

3,4-Difluorophenyl Evogliptin Tartrate

Chemical Name:3,4-Difluorophenyl Evogliptin TartrateSynonyms:(R)-4-{(R)-3-amino-4-(3,4-difluorophenyl)butanoyl}-3-(tbutoxymethyl)piperazin-2-one L-tartrateMolecular Formula:C₁₉H₂₇F₂N₃O₃ • (C₄H₆O₆)Molecular Weight:383.43 + (150.09)Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:3,4-Difluorophenyl Evogliptin Tartrate is an impurity of Evogliptin Tartrate (E945915) which is a useful intermediate used in the preparation of dipeptidyl peptidase-IV inhibitors and derivatives for the treatment of type 2 diabetes.References:Kim, J., et al.: Bioorg. Med. Chem. Lett., 21, 3809 (2011); […]

5-(4,4’-Dimethoxytrityl)-thymidine-d9-3-(cyanoethyl-N,N-diisopropyl) Phosphoramidite

Chemical Name:5-(4,4’-Dimethoxytrityl)-thymidine-d9-3-(cyanoethyl-N,N-diisopropyl) PhosphoramiditeAlternate CAS #:147566-44-7Molecular Formula:C₁₉H₂₂D₉N₄O₆PMolecular Weight:451.5Category:Research Tools; Chiral Molecules; Isotopic Labeled Analogues; Molecular Biology; Nucleic Acids; Carbohydrates and Oligosaccharides;Applications:5-(4,4’-Dimethoxytrityl)-thymidine-d9-3-(cyanoethyl-N,N-diisopropyl) Phosphoramidite is an isotopically labelled analog of 5-(4,4’-Dimethoxytrityl)-thymidine-3-(cyanoethyl-N,N-diisopropyl) Phosphoramidite (147566-44-7), which is a compound of research interes in the biological studies of mRNA imaging in cytoplasm and DNA tagging.References:Mhlanga, M., et. al.: Nucleic Acids Res., […]

4,6-Dimethyl-2-oxo-N-[1-(2-thiazolyl)-2-(2-thienyl)ethyl]-1(2H)-pyrimidinebutanamide

Chemical Name:4,6-Dimethyl-2-oxo-N-[1-(2-thiazolyl)-2-(2-thienyl)ethyl]-1(2H)-pyrimidinebutanamideSynonyms:4-(4,6-Dimethyl-2-oxopyrimidin-1(2H)-yl)-N-(1-(thiazol-2-yl)-2-(thiophen-2-yl)ethyl)butanamideCAS Number:1381553-21-4Molecular Formula:C₁₉H₂₂N₄O₂S₂Molecular Weight:402.53Category:Building Blocks; Standards; Miscellaneous;Applications:4,6-Dimethyl-2-oxo-N-[1-(2-thiazolyl)-2-(2-thienyl)ethyl]-1(2H)-pyrimidinebutanamide is an useful research chemicalsTo ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be […]

N2-[(2R)-4-[(1,1-Dimethylethoxy)amino]-2-(2-naphthalenylmethyl)-1,4-dioxobutyl]-N5-[[[2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl]sulfonyl]amino]iminoethyl-L-ornithine

Chemical Name:N2-[(2R)-4-[(1,1-Dimethylethoxy)amino]-2-(2-naphthalenylmethyl)-1,4-dioxobutyl]-N5-[[[2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl]sulfonyl]amino]iminoethyl-L-ornithineCAS Number:1093740-20-5Molecular Formula:C₃₈H₅₁N₅O₈SMolecular Weight:737.91Category:Research Tools;Applications:Intermediate in the synthesis of substrate-selective peptide hydroxamate inhibitor of insulin-degrading enzyme, N2-[(2R)-4-(Hydroxyamino)-2-(2-naphthalenylmethyl)-1,4-dioxobutyl]-L-arginyl-L-tryptophyl-L-α-glutamine (H828110).References:Abdul-Hay, S.O., et al.: J. Med. Chem., 56, 2246 (2013);To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with […]

2,2-Dimethyl Gibberellin A4

Chemical Name:2,2-Dimethyl Gibberellin A4Synonyms:(1α,2β,4aα,4bβ,10β)-2,4a-Dihydroxy-1,3,3-trimethyl-8-methylenegibbane-1,10-dicarboxylic Acid 1,4a-LactoneCAS Number:79035-06-6Molecular Formula:C₂₁H₂₈O₅Molecular Weight:360.44Category:Standards; Environmental Standards, Mutagens and Metabolites;Applications:2,2-Dimethyl Gibberellin A4 is a derivative of Gibberellic Acid (G377450), a hormone that is found in plants which promotes the growth and elongation of cells. Gibberellic acid acts as a plant growth regulator on account of its physiological and morphological effects in […]

1,7-Dimethyl-1H-imidazo[4,5-g]quinoxalin-2-amine

Chemical Name:1,7-Dimethyl-1H-imidazo[4,5-g]quinoxalin-2-amineSynonyms:2-Amino-1,7-dimethyl-1H-imidazo[4,5-g]quinoxaline; 7-MeIgQx;CAS Number:934333-16-1Molecular Formula:C₁₁H₁₁N₅Molecular Weight:213.24Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Environmental Standards, Mutagens and Metabolites;Applications:An abundant mutagenic heterocyclic aromatic amine (HAA) formed in cooked beef and other meats.References:Turesky, R.J. et al.: Chem. Res. Toxicol., 20, 520 (2007); Ni, W. et al.: J. Agric. Food Chem., 56, 68 (2008);To ensure the stability of our products, the efficient […]

6(7)-Dehydro Fulvestrant-9-sulfone

Chemical Name:6(7)-Dehydro Fulvestrant-9-sulfoneSynonyms:7alpha-[9-[(4,4,5,5,5-Pentafluoropentyl)sulfonyl]nonyl]estra-1,3,5(10),6(7)-tetraene-3,17beta-diolMolecular Formula:C₃₂H₄₅F₅O₄SMolecular Weight:620.75Category:Building Blocks;Applications:6(7)-Dehydro Fulvestrant-9-sulfone is a steroid and derivative compound of Fulvestrant (F862500). Fulvestrant is a novel steroidal estrogen antagonist reported to lack any partial agonist activity. Antineoplastic (hormonal).References:Wakeling, A.E., et al.: Cancer Res., 51, 3867 (1991), Howell, A., et al.: Br. J. Cancer, 74, 300 (1996), Robertson, J.F., et al.: Cancer […]

5,5-Dimethyl-3-(2-((7-methyl-2H-spiro[benzofuran-3,1′-cyclopropan]-4-yl)oxy)pyrimidin-5-yl)imidazolidine-2,4-dione

Chemical Name:5,5-Dimethyl-3-(2-((7-methyl-2H-spiro[benzofuran-3,1′-cyclopropan]-4-yl)oxy)pyrimidin-5-yl)imidazolidine-2,4-dioneSynonyms:Kv3 Modulator 1CAS Number:1380696-64-9Molecular Formula:C₂₀H₂₀N₄O₄Molecular Weight:380.4Category:Research Tools; Molecular Biology; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:5,5-Dimethyl-3-(2-((7-methyl-2H-spiro[benzofuran-3,1′-cyclopropan]-4-yl)oxy)pyrimidin-5-yl)imidazolidine-2,4-dione is a hydantoin derivative that functions as a Kv3 inhibitor for the treatment of pain and acute noise-induced hearing loss.References:Large, C.: From PCT Int. Appl. (2013), WO 2013175211 A1 20131128, Large, C., et al.: From PCT Int. Appl. (2017), WO 2017098254 A1 20170615To ensure the stability of our […]

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