6’-Exomethylene Lovastatin

Chemical Name:6’-Exomethylene LovastatinSynonyms:(2S)-2-Methyl-butanoic Acid (1S,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-7-methyl-3-methylene-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester;2-Methyl-butanoic acid [1S-[1α(R*),7β,8β(2S*,4S*),8aβ]]-1,2,3,7,8,8a-Hexahydro-7-methyl-3-methylene-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl EsterCAS Number:121624-17-7Molecular Formula:C₂₄H₃₄O₅Molecular Weight:402.52Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:6’-Exomethylene Lovastatin is a metabolite of Lovastatin (L472225) which is an antihypercholesterolemic agent.References:Bilheimer, D.W., et al.: Proc. Nat. Acad. Sci. USA, 80, 4124 (1983),To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee […]

N2,3-Etheno-2′-deoxy Guanosine-d3

Chemical Name:N2,3-Etheno-2′-deoxy Guanosine-d3Synonyms:1-(2-Deoxy-β-D-erythro-pentofuranosyl)-1H-imidazo[2,1-b]purin-4(5H)-one-d3;Alternate CAS #:121055-53-6Molecular Formula:C₁₂H₁₀D₃N₅O₄Molecular Weight:294.28Category:Standards; Isotopic Labeled Analogues; Carbohydrates and Oligosaccharides;Applications:A labelled etheno-substituted purine nucleoside derivative with fluorescent and biochemical properties. Etheno-DNA adducts are promutagenic lesions present in normal animal and human tissues that are believed to be important in the etiol. of cancer related to diet and lifestyle.References:Schlatter, J., et al.: Food […]

Fozivudine-D3

Chemical Name:Fozivudine-D3Alternate CAS #:141790-23-0Molecular Formula:C₃₅H₆₁D₃N₅O₈PSMolecular Weight:748.98Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Fozivudine-D3 is the labelled version of Fozivudine (F141000(M)), which is useful for preparing nanocontainers for transporting nonpolar and lipophilic substances such as antibiotics.References:Feldmann, C., et al.: Ger. Offen. (2019), DE 102018003770 A1To ensure the stability of our products, the efficient express delivery service will […]

(16β)- 17,21-[(1-Ethoxypropylidene)bis(oxy)]-16-methyl-pregna-1,4-diene-3,20-dione

Chemical Name:(16β)- 17,21-[(1-Ethoxypropylidene)bis(oxy)]-16-methyl-pregna-1,4-diene-3,20-dioneSynonyms:17,21-Dihydroxy-16β-methyl-pregna-1,4-diene-3,20-dione Cyclic Ethyl OrthopropionateMolecular Formula:C₂₇H₃₈O₅Molecular Weight:442.59Category:Standards; Steroids;Applications:(16β)- 17,21-[(1-Ethoxypropylidene)bis(oxy)]-16-methyl-pregna-1,4-diene-3,20-dione is an intermediate in the synthesis of Clobetasol Propionate Impurity E (C583505), an impurity of Clobetasol (C583490), which is a topical corticosteroid. Glucocorticoid; anti-inflammatory.References:Olsen, E.A., et al.: J. Am. Acad. Dermatol., 15, 246 (1986),To ensure the stability of our products, the efficient express delivery service […]

5-Fluoro-4-(7′-fluoro-2′-methylspiro[cyclopentane-1,3′-[3H]indol]-5′-yl)-N-[5-(1-methyl-4-piperidinyl)-2-pyridinyl]-2-pyrimidinamine

Chemical Name:5-Fluoro-4-(7′-fluoro-2′-methylspiro[cyclopentane-1,3′-[3H]indol]-5′-yl)-N-[5-(1-methyl-4-piperidinyl)-2-pyridinyl]-2-pyrimidinamineSynonyms:5-Fluoro-4-(7′-fluoro-2′-methylspiro[cyclopentane-1,3′-indol]-5′-yl)-N-(5-(1-methylpiperidin-4-yl)pyridin-2-yl)pyrimidin-2-amineCAS Number:2099128-41-1Molecular Formula:C₂₈H₃₀F₂N₆Molecular Weight:488.57Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:5-Fluoro-4-(7′-fluoro-2′-methylspiro[cyclopentane-1,3′-[3H]indol]-5′-yl)-N-[5-(1-methyl-4-piperidinyl)-2-pyridinyl]-2-pyrimidinamine is a novel CDK4/6 inhibitor which is designed to overcome blood brain barrier in gliobastoma therapy.References:Yin, L., et al.: Eur. J. Med. Chem., 144,1(2018)To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the […]

10-Methoxy Vinpocetine-d5

Chemical Name:10-Methoxy Vinpocetine-d5Synonyms:(13aS)-Ethyl 13a-Ethyl-8-methoxy-2,3,41,5,6,13a-hexahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylate-d5; Ethyl (13aS,13bS)-13a-Ethyl-10-methoxy-2,3,5,6,13a,13b-hexahydro-1H-indolo[3,2,1-de]-pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylate-d5(Vinpocetine Related Compound C)Alternate CAS #:E817935 Unlabelled (no cas#)Molecular Formula:C₂₃H₂₃D₅N₂O₃Molecular Weight:385.51Category:Research Tools;Applications:10-Methoxy Vinpocetine-d5 is labelled 10-Methoxy Vinpocetine-d5 (E817935) which is an impurity of Vinpocetine (V332500), a semisynthetic derivative of the alkaloid vincamine with vasodilating activity. Vinpocetine (V332500) has been also identified as a novel anti-inflammatory agent.References:Han, et al.: J. Biol. […]

Finerenone-D5

Chemical Name:Finerenone-D5Molecular Formula:C₂₁H₁₇D₅N₄O₃Molecular Weight:383.46Category:Standards; Isotopic Labeled Analogues;To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be wrapped with dried ice, and the […]

ethyl 3-(5-amino-2-(2-(4-hydroxy-2-methylphenyl)ethyl-1,1,2,2-d4)benzo[f][1,7]naphthyridin-8-yl)propanoate

Chemical Name:ethyl 3-(5-amino-2-(2-(4-hydroxy-2-methylphenyl)ethyl-1,1,2,2-d4)benzo[f][1,7]naphthyridin-8-yl)propanoateMolecular Formula:C26H23D4N3O3.2HClMolecular Weight:506.5To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be wrapped with dried ice, and the low temperature […]

ethyl 3-(5-amino-2-(4-hydroxy-2-methylphenethyl)benzo[f][1,7]naphthyridin-8-yl)propanoate dihydrochloride

Chemical Name:ethyl 3-(5-amino-2-(4-hydroxy-2-methylphenethyl)benzo[f][1,7]naphthyridin-8-yl)propanoate dihydrochlorideCAS Number:1268527-07-6Molecular Formula:C26H27N3O3.2HClMolecular Weight:502.43To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be wrapped with dried ice, and the […]

Estriol-d3 3-O-β-D-Glucuronide Sodium Salt

Chemical Name:Estriol-d3 3-O-β-D-Glucuronide Sodium SaltSynonyms:16α,17β-Dihydroxyestra-1,3,5(10)-trien-3-yl-d3 β-D-Glucopyranosiduronic Acid Monosodium Salt; 3-(β-D-Glucopyranuronosyloxy)-estra-1,3,5(10)-triene-16α,17β-diol-d3 Monosodium Salt; Estriol-d3 Sodium 3-Glucuronate; Sodium (2S,3S,4S,5R,6S)-6-(((8R,9S,13S,14S,16R,17R)-16,17-Dihydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylate-d3Alternate CAS #:Unlabelled: 15087-06-6; Unlabelled free acid: 2479Molecular Formula:C₂₄H₂₈D₃NaO₉Molecular Weight:489.51Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites; Steroids;Applications:Estriol-d3 3-O-β-D-Glucuronide Sodium Salt is the labeled analogue of Estriol 3-O-β-D-Glucuronide Sodium Salt (E888977), a metabolite found in the urine of pregnant women.References:Simkins, […]

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