Chemical Name:Hydroxy CobicistatSynonyms:Thiazol-5-ylmethyl ((2R,5R)-5-((S)-2-(3-((2-(2-Hydroxypropan-2-yl)thiazol-4-yl)methyl)-3-methylureido)-4-morpholinobutanamido)-1,6-diphenylhexan-2-yl)carbamateCAS Number:1051463-40-1Molecular Formula:C₄₀H₅₃N₇O₆S₂Molecular Weight:792.02Category:Standards; Enzyme Activators and Inhibitors;Applications:Hydroxy Cobicistat is a derivative of Cobicistat (C633150), a HIV protease inhibitor that has been coadministered with low-dose ritonavir (R535000) as a pharmacoenhancer.References:Von, H., Exp. Rev. Clin. Pharmacol., 5, 557 (2012); Lepist, E.I., et al.: Antimicrob. Agent. Chemother., 56, 5409 (2012); Orr, S.T.M., et al.: […]

Chemical Name:(αS,​3aR,​8aS)​-Hexahydro-​2,​2-​dimethyl-​7-​oxo-​α-​[[(phenylmethoxy)​carbonyl]​amino]​-​5H-​1,​3-​dioxolo[4,​5-​c]​azepine-​5-​hexanoic Acid Phenylmethyl EsterSynonyms:(S)-Benzyl 2-(((Benzyloxy)carbonyl)amino)-6-((3aR,8aS)-2,2-dimethyl-7-oxotetrahydro-3aH-[1,3]dioxolo[4,5-c]azepin-5(4H)-yl)hexanoateCAS Number:1820794-38-4Molecular Formula:C₃₀H₃₈N₂O₇Molecular Weight:538.63Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:(αS,​3aR,​8aS)​-Hexahydro-​2,​2-​dimethyl-​7-​oxo-​α-​[[(phenylmethoxy)​carbonyl]​amino]​-​5H-​1,​3-​dioxolo[4,​5-​c]​azepine-​5-​hexanoic Acid Phenylmethyl Ester is an intermediate in synthesizing 6R,7S,8aR-Glucosepane Tri-TFA Salt (G595310), one of the eight diastereomers of glucosepane. Glucosepane is a structurally complex protein posttranslational modification that is believed to exist in all living organisms. Research in humans suggests that glucosepane plays […]

Chemical Name:(4S,12aS)-3,4,6,8,12,12a-Hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic Acid(Dolutegravir Impurity)Alternate CAS #:4R: 1246616-73-8Molecular Formula:C₁₄H₁₆N₂O₆Molecular Weight:308.29Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:(4S,12aS)-3,4,6,8,12,12a-Hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic Acid, is an impurity of Dolutegravir (D528800), which is a second generation HIV-1 integrase strand transfer inhibitor.References:Kobayashi, M. et al. Antimicrob Agents Chemother., 55, 813 (2011); Garrido, C. et al.: Antiviral, Res., 90, 164 (2011); Lenz, J.C.C. et al.: Exp. Opin. Invest. Drugs, […]

Chemical Name:Hexanoyl Docetaxel Hydroxy tert-ButylcarbamateSynonyms:(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-Acetoxy-9-(((2R,3S)-2-(hexanoyloxy)-3-((((1-hydroxy-2-methylpropan-2-yl)oxy)carbonyl)amino)-3-phenylpropanoyl)oxy)-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl BenzoateMolecular Formula:C₄₉H₆₃NO₁₆Molecular Weight:922.02Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Hexanoyl Docetaxel Hydroxy tert-Butylcarbamate is an analogue of Docetaxel Hydroxy tert-Butylcarbamate (D494425), the main metabolite of Docetaxel (D494420), an antineoplastic.References:Commercon, A., et al.: Tetrahedron, 50, 34, 10289 (1994)To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee […]

Chemical Name:N-[2-Hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl](phenylmethyl)amino]ethyl]phenyl]formamideCAS Number:1337876-26-2Molecular Formula:C₂₆H₃₀N₂O₄Molecular Weight:434.5Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:N-[2-Hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl](phenylmethyl)amino]ethyl]phenyl]formamide,is an impurity of Arformoterol Tartrate (A767505) which is a long-acting β2 adrenoreceptor agonist (LABA) indicated for the treatment of chronic obstructive pulmonary disease (COPD).References:Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983); Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984); Morii, M., et al.: J. Biol. […]

Chemical Name:9-Hydroxy PrednisoloneSynonyms:Prednisolone ImpurityMolecular Formula:C₂₁H₂₈O₅Molecular Weight:360.44Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:9-Hydroxy Prednisolone, is a metabolite of Prednisolone (P703740), a synthetic corticosteroid; metabolically interconvertible with prednisone. Hydrocortisone EP Impurity A.References:Jusko, W.J., et al.: Ther. Drug Monit., 2, 169 (1980); Ali, S.L., et al.: Anal. Profiles Drug Subs. Excip., 21, 415 (1992);To ensure the stability of our products, the […]

Chemical Name:Hesperetin 7-O-Glucoside-d3Molecular Formula:C22H21D3O11Molecular Weight:467.4Category:Building Blocks; Isotopic Labeled Analogues; Miscellaneous;Applications:Hesperetin 7-O-Glucoside-d3 is a useful research chemical compound.To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low […]

Chemical Name:7-Hydroxy SolanidineSynonyms:(4S,6aR,6bS,8aS,8bR,9S,9aR,12S,14aS,15aS,15bS)-6a,8a,9,12-tetramethyl-3,4,5,6,6a,6b,7,8,8a,8b,9,9a,10,11,12,13,14a,15,15a,15b-icosahydro-1H-naphtho[2′,1′:4,5]indeno[1,2-b]indolizine-1,4-diolCAS Number:911476-37-4Molecular Formula:C₂₇H₄₃NO₂Molecular Weight:413.6Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Environmental Standards, Mutagens and Metabolites;Applications:7-Hydroxy Solanidine is an impurity of Solanidine(S682400). Soladine has been shown to display mutagenic properties in the liver, and is stored in the body for prolonged periods of time.References:Crawford, L.; et al.: Food Chem Toxicol., 33, 191 (1995), Claringbold, W. D. B.; […]

Chemical Name:4-(4-Hydroxy-1,1-dioxido-1,2-thiazinan-2-yl)benzenesulfonamideAlternate CAS #:61-56-3Molecular Formula:C₁₀H₁₄N₂O₅S₂Molecular Weight:306.35To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be wrapped with dried ice, and the low […]

Chemical Name:HalofuginoneSynonyms:rel-7-Bromo-6-chloro-3-[3-[(2R,3S)-3-hydroxy-2-piperidinyl]-2-oxopropyl]-4(3H)-quinazolinone;CAS Number:55837-20-2Molecular Formula:C16H17BrClN3O3Molecular Weight:414.68Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Halofuginone is a halogenated derivative of Febrifugine (F228500). Halofuginone is used as an antiprotozoal.References:Ryley, J.G., et al.: Parasitology, 70, 203 (1975),To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with […]