3-Hydroxy Cyclobenzaprine-d6

Chemical Name:3-Hydroxy Cyclobenzaprine-d6Synonyms:5-[3-(Dimethylamino)propylidene]-5H-dibenzo[a,d]cyclohepten-3-ol-d6;CAS Number:1217246-95-1Alternate CAS #:unlabelled: 30235-48-4Molecular Formula:C₂₀H₁₅D₆NOMolecular Weight:297.42Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;Applications:A labelled metabolite of Cyclobenzaprine (C987750).References:Hucker, H.B., et al.: Drug Metab. Dispos., 6, 184-92 (1978),To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box […]

4-Hydroxy-Tamoxifen Acyl-glucuronide

Chemical Name:4-Hydroxy-Tamoxifen Acyl-glucuronideMolecular Formula:C₃₃H₃₇NO₁₀Molecular Weight:607.65Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:4-Hydroxy-Tamoxifen Acyl-glucuronide, is an impurity of Tamoxifen (T006000), a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor.References:Sutherland, R., et al.: Nature, 267, 434 (1977), Lerner, L., et al.: Cancer Res., 50, 4177 (1990), Love, R., et al.: J. Clin. Oncol., 20 2559 (2002),To ensure […]

trans,trans-4-Heptylbicyclohexyl-4-nitrile

Chemical Name:trans,trans-4-Heptylbicyclohexyl-4-nitrileSynonyms:trans,trans-p-Heptyl-p’-cyanobicyclohexyl; trans,trans-4-Cyano-4′-heptyl-1,1′-bicyclohexyl; trans,trans-4-(4′-Heptylcyclohexyl)cyanocyclohexane; (trans,trans)-4′-Heptyl[1,1′-bicyclohexyl]-4-carbonitrileCAS Number:65355-37-5Molecular Formula:C₂₀H₃₅NMolecular Weight:289.5Category:Building Blocks; Miscellaneous;Applications:trans,trans-4-Heptylbicyclohexyl-4-nitrile is a nematic liquid crystal solvent used for polarization.References:Beek, L, C. et al,: Chem. Phy. Lett., 426(1-3), 96-99 (2006)To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with […]

(R)-7-Hydroxy Efavirenz

Chemical Name:(R)-7-Hydroxy EfavirenzSynonyms:(R)-6-Chloro-4-(cyclopropylethynyl)-7-hydroxy-4-(trifluoromethyl)-1H-benzo[d][1,3]oxazin-2(4H)-oneMolecular Formula:C₁₄H₉ClF₃NO₃Molecular Weight:331.67Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Anti-virals/Anti-retrovirals;Applications:(R)-7-Hydroxy Efavirenz, is a metabolite of Efavirenz (E425000), a nonnucleoside HIV-1 reverse transcriptase inhibitor. Antiviral.References:Young, S.D., et al.: Antimicrob. Ag. Chemother., 39, 2602 (1995),To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped […]

4-(2-Hydroxy-1-(4-hydroxy-3-(hydroxymethyl)-5-methylpyridin-2-yl)ethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol

Chemical Name:4-(2-Hydroxy-1-(4-hydroxy-3-(hydroxymethyl)-5-methylpyridin-2-yl)ethyl)-5-(hydroxymethyl)-2-methylpyridin-3-olMolecular Formula:C₁₆H₂₀N₂O₅Molecular Weight:320.25Category:Building Blocks; Miscellaneous;Applications:4-(2-Hydroxy-1-(4-hydroxy-3-(hydroxymethyl)-5-methylpyridin-2-yl)ethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol is a useful intermediate for organic synthesis.To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be […]

18-Hydroxy Corticosterone-d8

Chemical Name:18-Hydroxy Corticosterone-d8Synonyms:(11β)-11,18,21-Trihydroxypregn-4-ene-3,20-dione-d8; 11β,18,21-Trihydroxypregn-4-ene-3,20-dione-d8; 18-Hydroxycorticosterone-d8;Alternate CAS #:561-65-9-unlabelledMolecular Formula:C₂₁H₂₂D₈O₅Molecular Weight:370.51Category:Building Blocks; Isotopic Labeled Analogues;Applications:Labelled 18-Hydroxycorticosterone (H824960). 18-Hydroxycorticosterone is a derivative of Corticosterone. 18-Hydroxycorticosterone is used as an intermediate in the synthesis of Aldosterone (A514700).References:Mulatero, P., et al.: J. Clin. Endocrinol. Metab., 83, 3996 (1998); Funder, J., et al.: J. Clin. Endocrinol. Metab., 93, 3266 (2008); Mulatero, […]

(+)-Horsfiline

Chemical Name:(+)-HorsfilineSynonyms:(3S)-5-Methoxy-1′-methylspiro[3H-indole-3,3′-pyrrolidin]-2(1H)-one; (S)- 5-methoxy-1′-methylspiro[3H-indole-3,3′-pyrrolidin]-2(1H)-one;CAS Number:160024-53-3Molecular Formula:C₁₃H₁₆N₂O₂Molecular Weight:232.28Category:Standards; Natural Products;Applications:(+)-Horsfiline, is an oxindole alkaloid found in the plant Horsfieldia superba, which is used in traditional herbal medicine. It has analgesic effects and has been the subject of significant research both to produce it synthetically by convenient routes,and to develop analogues and derivatives which may have improved […]

1-Hydroxy Carvedilol-d3 1-O-β-D-Glucuronide

Chemical Name:1-Hydroxy Carvedilol-d3 1-O-β-D-GlucuronideSynonyms:4-[2-Hydroxy-3-[[2-(2-methoxy-d3-phenoxy)ethyl]amino]propoxy]-9H-carbazol-1-yl β-D-Glucopyranosiduronic AcidAlternate CAS #:Unlabelled: 131087-98-4Molecular Formula:C₃₀H₃₁D₃N₂O₁₁Molecular Weight:601.62Category:Building Blocks; Isotopic Labeled Analogues;Applications:1-Hydroxy Carvedilol-d3 1-O-β-D-Glucuronide is the labeled analogue of 1-Hydroxy Carvedilol 1-O-β-D-Glucuronide (H825035), a metabolite of Carvedilol (C184625) found in humans, rats, dogs and mice.References:Schaefer, W.H. et al.: Drug. Metab. Dispos., 26, 958 (1998); Fujimaki, M. & Hakusui, H.: Xenobiotica, 20, 1025 […]

(-)-Horsfiline

Chemical Name:(-)-HorsfilineSynonyms:(3R)-5-Methoxy-1′-methylspiro[3H-indole-3,3′-pyrrolidin]-2(1H)-one; (R)- 5-methoxy-1′-methylspiro[3H-indole-3,3′-pyrrolidin]-2(1H)-one;CAS Number:136247-72-8Molecular Formula:C₁₃H₁₆N₂O₂Molecular Weight:232.28Category:Standards; Natural Products;Applications:(-)-Horsfiline, is an oxindole alkaloid found in the plant Horsfieldia superba, which is used in traditional herbal medicine. It has analgesic effects and has been the subject of significant research both to produce it synthetically by convenient routes,and to develop analogues and derivatives which may have improved […]

Hydroxy Cobicistat

Chemical Name:Hydroxy CobicistatSynonyms:Thiazol-5-ylmethyl ((2R,5R)-5-((S)-2-(3-((2-(2-Hydroxypropan-2-yl)thiazol-4-yl)methyl)-3-methylureido)-4-morpholinobutanamido)-1,6-diphenylhexan-2-yl)carbamateCAS Number:1051463-40-1Molecular Formula:C₄₀H₅₃N₇O₆S₂Molecular Weight:792.02Category:Standards; Enzyme Activators and Inhibitors;Applications:Hydroxy Cobicistat is a derivative of Cobicistat (C633150), a HIV protease inhibitor that has been coadministered with low-dose ritonavir (R535000) as a pharmacoenhancer.References:Von, H., Exp. Rev. Clin. Pharmacol., 5, 557 (2012); Lepist, E.I., et al.: Antimicrob. Agent. Chemother., 56, 5409 (2012); Orr, S.T.M., et al.: […]

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