Chemical Name:4-Hydroxycarbazeran-d4Synonyms:1-(3,4-Dihydro-6,7-dimethoxy-4-oxo-1-phthalazinyl)-4-piperidinyl Ester Ethylcarbamic Acid-d4;Alternate CAS #:Unlabelled: 96724-43-5Molecular Formula:C₁₈H₂₀D₄N₄O₅Molecular Weight:380.43Category:Building Blocks; Isotopic Labeled Analogues;Applications:4-Hydroxycarbazeran-d4 is the isotope labelled analog of 4-Hydroxycarbazeran, a metabolite of Carbazeran (C175790). Carbazeran is known as a phosphodiesterase inhibitor drug that exhibits chronictropic and inotropic effects.References:Kaye, B., et al.: Xenobiotica., 15, 237 (1985); Shahid, M., et al.: Br. J. Pharmacol., 98, 291 […]

Chemical Name:7β-HydroxygliclazideSynonyms:rel-(3aα,5α,6aα)-N-[[(Hexahydro-5-hydroxycyclopenta[c]pyrrol-2(1H)-yl)amino]carbonyl]-4-methyl-benzenesulfonamide; 5-Hydroxy-hexahydro-cyclopenta[c]pyrrole BenzenesulfonamideCAS Number:96860-48-9Molecular Formula:C₁₅H₂₁N₃O₄SMolecular Weight:339.41Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:7β-Hydroxygliclazide is a metabolite of Gliclazide (G409875) which is a a sulfonylurea hypoglycemic agent used as an antidiabetic.References:Duhault, J., et al.: Arzneimittel-Forsch., 22, 1686 (1972), Holmes, B., et al.: Drugs, 27, 301 (1984),To ensure the stability of our products, the efficient express delivery service will be […]

Chemical Name:13-Hydroxy CabotegravirSynonyms:(3S,11aR)-N-(2,4-Difluorobenzyl)-2,6-dihydroxy-3-methyl-5,7-dioxo-2,3,5,7,11,11a-hexahydrooxazolo[3,2-a]pyrido[1,2-d]pyrazine-8-carboxamideMolecular Formula:C₁₉H₁₇F₂N₃O₆Molecular Weight:421.35Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:13-Hydroxy Cabotegravir is a metabolite of Cabotegravir (C050100). Cabotegravir is a long acting HIV-1 integrase inhibitor with action against a broad range of HIV subtypes.References:Yoshinaga, T. et al.: Antimicrob, Agents Chemother., 59, 397 (2015); Andrews, C. et al.: Sci. Transl. Med., 7, 270 (2015)To […]

Chemical Name:13-Hydroxy Cabotegravir-d3Synonyms:(3S,11aR)-N-(2,4-Difluorobenzyl)-2,6-dihydroxy-3-methyl-5,7-dioxo-2,3,5,7,11,11a-hexahydrooxazolo[3,2-a]pyrido[1,2-d]pyrazine-8-carboxamide-d3Molecular Formula:C₁₉H₁₄D₃F₂N₃O₆Molecular Weight:424.37Category:Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:13-Hydroxy Cabotegravir-d3 is the labelled form of 13-Hydroxy Cabotegravir. 13-Hydroxy Cabotegravir is a metabolite of Cabotegravir (C050100). Cabotegravir is a long acting HIV-1 integrase inhibitor with action against a broad range of HIV subtypes.References:Yoshinaga, T. et al.: Antimicrob, Agents Chemother., 59, […]

Chemical Name:24-Hydroxy CabotegravirSynonyms:(3S,11aR)-N-(2,4-Difluoro-3-hydroxybenzyl)-6-hydroxy-3-methyl-5,7-dioxo-2,3,5,7,11,11a-hexahydrooxazolo[3,2-a]pyrido[1,2-d]pyrazine-8-carboxamideMolecular Formula:C₁₉H₁₇F₂N₃O₆Molecular Weight:421.35Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:24-Hydroxy Cabotegravir is a metabolite of Cabotegravir (C050100). Cabotegravir is a long acting HIV-1 integrase inhibitor with action against a broad range of HIV subtypes.References:Yoshinaga, T. et al.: Antimicrob, Agents Chemother., 59, 397 (2015); Andrews, C. et al.: Sci. Transl. Med., 7, 270 (2015)To […]

Chemical Name:24-Hydroxy Cabotegravir-d3Synonyms:(3S,11aR)-N-(2,4-Difluoro-3-hydroxybenzyl)-6-hydroxy-3-methyl-5,7-dioxo-2,3,5,7,11,11a-hexahydrooxazolo[3,2-a]pyrido[1,2-d]pyrazine-8-carboxamide-d3Molecular Formula:C₁₉H₁₄D₃F₂N₃O₆Molecular Weight:424.37Category:Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:24-Hydroxy Cabotegravir-d3 is the labelled form of 24-Hydroxy Cabotegravir. 24-Hydroxy Cabotegravir is a metabolite of Cabotegravir (C050100). Cabotegravir is a long acting HIV-1 integrase inhibitor with action against a broad range of HIV subtypes.References:Yoshinaga, T. et al.: Antimicrob, Agents Chemother., 59, […]

Chemical Name:6-​β-​Hydroxycortisol-d4 SulfateSynonyms:6-β-Hydroxycortisol-d4 MonosulfateAlternate CAS #:Unlabelled: 53587-06-7Molecular Formula:C₂₁H₂₆D₄O₉SMolecular Weight:462.55Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Steroids;Applications:Isotope labelled 6-β-Hydroxycortisol Sulfate is used in the synthesis of corticosteroids in human blood.References:Miyabo, S. et al.: J. Steroid. Biochem., 5, 233 (1974);To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products […]

Chemical Name:3,16-Dihydroxycorticosterone 20-Hydroxy-21-AcidMolecular Formula:C₂₁H₃₂O₆Molecular Weight:380.48Category:Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; Steroids;Applications:3,16-Dihydroxycorticosterone 20-Hydroxy-21-Acid is a derivative of Corticosterone (C695700), an intermediate in the biosynthesis of Aldosterone (A514700), isolated from the adrenal cortex.References:Schmidt, M., et al.: Endocrinol., 150, 2709 (2009), Bailey, M., et al.: J. Immunol., 182, 7888 (2009), Brunton, P., et al.: J. Neurosci., 29, 6449 […]

Chemical Name:3-Hydroxy Cyclobenzaprine-d6Synonyms:5-[3-(Dimethylamino)propylidene]-5H-dibenzo[a,d]cyclohepten-3-ol-d6;CAS Number:1217246-95-1Alternate CAS #:unlabelled: 30235-48-4Molecular Formula:C₂₀H₁₅D₆NOMolecular Weight:297.42Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;Applications:A labelled metabolite of Cyclobenzaprine (C987750).References:Hucker, H.B., et al.: Drug Metab. Dispos., 6, 184-92 (1978),To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box […]

Chemical Name:6’-Hydroxy DelavirdineSynonyms:N-[2-[[4-[1,6-Dihydro-3-[(1-methylethyl)amino]-6-oxo-2-pyridinyl]-1-piperazinyl]carbonyl]-1H-indol-5-yl]methanesulfonamide; 1-[1,6-Dihydro-3-[(1-methylethyl)amino]-6-oxo-2-pyridinyl]-4-[[5-[(methylsulfonyl)amino]-1H-indol-2-yl]carbonyl]piperazineCAS Number:188780-44-1Molecular Formula:C₂₂H₂₈N₆O₄SMolecular Weight:472.56Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:6’-Hydroxy Delavirdine is a metabolite of Delavirdine (D230625); a bisheteroarylpiperazine (BHAP) reverse transcriptase inhibitor.References:Dueweke, T.J., et al.: Antimicrob. Ag. Chemother., 37, 1127 (1993); Althaus, I.W., et al.: Biochem. Pharmacol., 47, 2017 (1994); Voorman, R.L., et al.: J. Pharmacol. Exp. Ther., 287, 381 (1998)To ensure the stability […]