Chemical Name:N-Hydroxyaristolactam ISynonyms:6-Hydroxy-8-methoxybenzo[f]-1,3-benzodioxolo[6,5,4-cd]indol-5(6H)-oneCAS Number:944954-53-4Molecular Formula:C₁₇H₁₁NO₅Molecular Weight:309.27Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:N-Hydroxyaristolactam I, is a derivative of Aristolactam I (A767420), classified as human carcinogen associated with human nephropathy and urothelial cancer.References:Stiborova, M. et al.: Toxicol. Sci., 125, 345 (2012);To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the […]

Chemical Name:2-Hydroxy ValbenazineSynonyms:(S)-(2R,3R,11bR)-3-(2-Hydroxypropan-2-yl)-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-yl 2-amino-3-methylbutanoateMolecular Formula:C₂₃H₃₆N₂O₅Molecular Weight:420.54Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:2-Hydroxy Valbenazine is an impurity of Valbenazine (V087000), a highly selective vesicular monoamine transporter 2 inhibitor. It is used in the treatment of tardive dykinesia.References:O’Brien, C. et al.: Movement Dis., 30, 1681 (2015);To ensure the stability of our products, the efficient express delivery service will be used. […]

Chemical Name:trans-4-Hydroxy-L-proline-d6Synonyms:(-)-4-Hydroxy-2-pyrrolidinecarboxylic Acid-d6; (2S,4R)-(-)-4-Hydroxyproline-d6; (R)-4-Hydroxy-(S)-proline-d6; 4(R)-Hydroxy-2(S)-pyrrolidinecarboxylic Acid-d6; 4-trans-Hydroxy-L-proline-d6; L-Hypro-d6; NSC 46704-d6;Alternate CAS #:unlabelled: 51-35-4Molecular Formula:C₅H₃D₆NO₃Molecular Weight:137.17Category:Building Blocks; Isotopic Labeled Analogues;Applications:trans-4-Hydroxy-L-proline-d9 is deuterium labelled trans-4-Hydroxy-L-proline (H952376). A natural constituent of animal structural proteins such as collagen and elastin. Several microorganisms producing proline trans-4- and cis-3-hydroxylase were discovered and these enzymes were applied to the industrial production of trans-4- […]

Chemical Name:Ibrutinib M25Synonyms:4-Amino-γ-[[(1-oxo-2-propen-1-yl)amino]methyl]-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine-1-butanoic AcidCAS Number:1839090-60-6Molecular Formula:C₂₅H₂₄N₆O₄Molecular Weight:472.5Category:Research Tools; Standards; Molecular Biology; Enzyme Activators and Inhibitors;Applications:Ibrutinib M25, is an impurity of Ibrutinib (I124970), a highly selective Bruton’s tyrosine kinase (Btk) irreversible inhibitor.References:MacGlashan, D., et. al.: Int. Immunol., 11, 475 (2011)To ensure the stability of our products, the efficient express delivery service will be used. We also […]

Chemical Name:2-(2-Hydroxy-2-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)acetamido)-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoic Acid, Amide-BridgedSynonyms:O-(4-Hydroxy-3,5-diiodophenyl)-N-[2-hydroxy-2-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]acetyl]-3,5-diiodotyrosine;Alternate CAS #:Parent compound: 51-48-9Molecular Formula:C₂₉H₁₇I₈NO₈Molecular Weight:1522.68Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:2-(2-Hydroxy-2-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)acetamido)-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoic Acid, Amide-Bridged is a Levothyroxine impurity of Thyroxine (T425600), which is one of the thyroid hormones involved in the maintenance of metabolic homeostasis. Thyroxine is deiodinated in peripheral tissues to the active metabolite, liothyronine, which has been used to treat hyperlipidemia.References:Post, A., […]

Chemical Name:4,4’-(8-Fluoropentaazaphenalene-2,5-diyl)bis((N3-methyl)triphenylamine)Synonyms:I-423;4,4′-(8-Fluoro-1,3,3a1,4,6-pentaazaphenalene-2,5-diyl)bis(N3-methyl-N1,N1-diphenylbenzene-1,3-diamine);Molecular Formula:C₄₆H₃₆FN₉Molecular Weight:733.86Category:Building Blocks; Miscellaneous;Applications:I-423 is a useful research chemical.To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be wrapped with […]

Chemical Name:all-trans-18-Hydroxy Retinoic AcidSynonyms:18-Hydroxy-all-trans-retinoic acid; 18-Hydroxyretinoic acid; Ro 12-4825;CAS Number:63531-93-1Molecular Formula:C₂₀H₂₈O₃Molecular Weight:316.43Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:all-trans-18-Hydroxy Retinoic Acid is hydroxylated metabolite of all-trans-Retinoic Acid (R250200) produce by cytochrome P450, CYP26C1.References:Taimi, M. et al.: J. Biol. Chem., 279, 77 (2004); Idres, N. et al.: J. Biol. Chem., 277, 31491 (2002); Hanni, R. et al.: Helv. Chim. Acta, […]

Chemical Name:N-(6-(3-(4-(Bis(methyl-d3)amino)butoxy)-5-propoxyphenoxy)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)-3,4-dimethoxybenzenesulfonamideMolecular Formula:C32H36D6N4O8SMolecular Weight:648.8Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;Applications:N-(6-(3-(4-(Bis(methyl-d3)amino)butoxy)-5-propoxyphenoxy)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)-3,4-dimethoxybenzenesulfonamide is a useful research chemical compoundTo ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature […]

Chemical Name:Hydroxy Saxagliptin-13C,D2 HydrochlorideSynonyms:(1S,3S,5S)-2-[(2S)-2-amino-2-(3,5-dihydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-2-Azabicyclo[3.1.0]hexane-3-carbonitrile-13C,D2 Hydrochloride; BMS 510849–13C,D2 Hydrochloride; 5-Hydroxy Saxagliptin-13C,D2 Hydrochloride; BMS 510849-13C,D2 Hydrochloride; M2 Saxagliptin Hydroxylated Metabolite-13C,D2 Hydrochloride;CAS Number:1572922-53-2Alternate CAS #:Unlabelled : 841302-24-7Free Base: 1573403-06-1Molecular Formula:C₁₇¹³CH₂₄D₂ClN₃O₃Molecular Weight:370.88Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Isotope labelled Hydroxy-Saxagliptin. a metabolite of Saxagliptin (S143500).References:Patel, C. et al.: J. Clinic. Pharmacol., 50, 1211 (2010); Feng, J., et al.: J. Med. Chem., 50, […]

Chemical Name:(R)-1-(4-Hydroxy-2-(2-hydroxypropan-2-yl)-2,3-dihydrobenzofuran-5-yl)-3-phenylpropan-1-oneMolecular Formula:C₂₀H₂₂O₄Molecular Weight:326.39Category:Building Blocks; Miscellaneous;Applications:(R)-1-(4-Hydroxy-2-(2-hydroxypropan-2-yl)-2,3-dihydrobenzofuran-5-yl)-3-phenylpropan-1-one is a pharmaceutical intermediate.To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be wrapped with dried […]