Chemical Name:1H-Imidazole-4,5-13C2-15N2CAS Number:NAMolecular Formula:C13C2H415N2Molecular Weight:72.05Applications:1H-Imidazole-4,5-13C2-15N2 is a useful research chemical.To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be wrapped with dried […]
Indacaterol-d10
Chemical Name:Indacaterol-d10Alternate CAS #:312753-06-3Molecular Formula:C₂₄H₁₈D₁₀N₂O₃Molecular Weight:402.55Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:A labeled Indacaterol (I499745) which is a β-adrenoreceptor agonists for treatment of asthma and bronchodilator treatment for patients with chronic obstructive pulmonary diseases.References:Crisafulli, E., et al.; Expert Opinion Pharmacother., 18, 1499 (2017); Aparici, M., et al.: Pul. Pharmacol. Ther., 46, 1 (2017); Demin, I., et al.: Int. […]
1-Hydroxy-3-methylcholanthrene
Chemical Name:1-Hydroxy-3-methylcholanthreneSynonyms:1,2-Dihydro-3-methyl-benz[j]aceanthrylen-1-ol; 3-Methyl-1-cholanthrenol (7CI,8CI); 2-Dihydro-3-methylbenz[j]aceanthrylen-1-ol; 3-Methylcholanthren-1-olCAS Number:3342-98-1Alternate CAS #:Parent compound: 56-49-5Molecular Formula:C₂₁H₁₆OMolecular Weight:284.35Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:1-Hydroxy-3-methylcholanthrene is a major metabolite of 2-Methylcholanthrene and has been shown to exhibit carcinogenicity in rats at the site of injection, causing sarcomas in 42% of rats subjected to testing within 52 weeks of initial injection.References:Flesher, J.W.; et al.: Biochem. […]
2-Hydroxy-3-methylcholanthrene
Chemical Name:2-Hydroxy-3-methylcholanthreneSynonyms:3-Methyl-2-cholanthrenol (7CI, 8CI); 1,2-Dihydro-3-methylbenz[j]aceanthrylen-2-ol; 3-Methylcholanthren-2-olCAS Number:3308-64-3Alternate CAS #:Parent compound: 56-49-5Molecular Formula:C₂₁H₁₆OMolecular Weight:284.35Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:2-Hydroxy-3-methylcholanthrene is a metabolite of 3-Methylcholanthrene, which is formed by liver microsomes in rats. The metabolism of the racemic mixture of 2-Hydroxy-3-methylcholanthrene was found to be enantiospecific; the rate of metabolism of the R isomer is faster than that of […]
3-Hydroxymethylcholanthrene trans-9,10-Dihydrodiol
Chemical Name:3-Hydroxymethylcholanthrene trans-9,10-DihydrodiolSynonyms:(9S-trans)-1,2,9,10-Tetrahydro-3-(hydroxymethyl)-benz[j]aceanthrylene-9,10-diolAlternate CAS #:177472-67-2 (S,S, trans); 177327-80-9 (R,R, trans)Molecular Formula:C₂₁H₁₈O₃Molecular Weight:318.37Category:Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;Applications:3-Hydroxymethylcholanthrene trans-9,10-Dihydrodiol has been shown to be a metabolite of 3-Hydroxymethylcholanthrene (3-OHMC) when incubated with rat liver microsomes.References:Shou, M.; et al.: Drug Metab. Dispos, 24, 595 (1996)To ensure the stability of our products, the efficient express delivery service will […]
3-Hydroxymethylcholanthrene-1-one
Chemical Name:3-Hydroxymethylcholanthrene-1-oneSynonyms:3-(hydroxymethyl)-benz[j]aceanthrylen-1(2H)-one (9CI)CAS Number:177237-83-2Alternate CAS #:Parent compound: 56-49-5Molecular Formula:C₂₁H₁₄O₂Molecular Weight:298.33Category:Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;Applications:3-Hydroxymethylcholanthrene-1-one has been shown to be a metabolite of 3-Hydroxymethylcholanthrene (3-OHMC) when incubated with rat liver microsomes.References:Shou, M.; et al.: Drug Metab. Dispos, 24, 595 (1996)To ensure the stability of our products, the efficient express delivery service will be used. We […]
3-Hydroxymethylcholanthrene-2-one
Chemical Name:3-Hydroxymethylcholanthrene-2-oneSynonyms:3-(Hydroxymethyl)-benz[j]aceanthrylen-2(1H)-one (9CI)CAS Number:177327-84-3Alternate CAS #:Parent compound: 56-49-5Molecular Formula:C₂₁H₁₄O₂Molecular Weight:298.33Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:3-Hydroxymethylcholanthrene-2-one has been shown to be a metabolite of 3-Hydroxymethylcholanthrene (3-OHMC) when incubated with rat liver microsomes.References:Shou, M.; et al.: Drug Metab. Dispos, 24, 595 (1996)To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee […]
N-Hydroxyaristolactam I
Chemical Name:N-Hydroxyaristolactam ISynonyms:6-Hydroxy-8-methoxybenzo[f]-1,3-benzodioxolo[6,5,4-cd]indol-5(6H)-oneCAS Number:944954-53-4Molecular Formula:C₁₇H₁₁NO₅Molecular Weight:309.27Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:N-Hydroxyaristolactam I, is a derivative of Aristolactam I (A767420), classified as human carcinogen associated with human nephropathy and urothelial cancer.References:Stiborova, M. et al.: Toxicol. Sci., 125, 345 (2012);To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the […]
2-Hydroxy Valbenazine
Chemical Name:2-Hydroxy ValbenazineSynonyms:(S)-(2R,3R,11bR)-3-(2-Hydroxypropan-2-yl)-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-yl 2-amino-3-methylbutanoateMolecular Formula:C₂₃H₃₆N₂O₅Molecular Weight:420.54Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:2-Hydroxy Valbenazine is an impurity of Valbenazine (V087000), a highly selective vesicular monoamine transporter 2 inhibitor. It is used in the treatment of tardive dykinesia.References:O’Brien, C. et al.: Movement Dis., 30, 1681 (2015);To ensure the stability of our products, the efficient express delivery service will be used. […]
trans-4-Hydroxy-L-proline-d6
Chemical Name:trans-4-Hydroxy-L-proline-d6Synonyms:(-)-4-Hydroxy-2-pyrrolidinecarboxylic Acid-d6; (2S,4R)-(-)-4-Hydroxyproline-d6; (R)-4-Hydroxy-(S)-proline-d6; 4(R)-Hydroxy-2(S)-pyrrolidinecarboxylic Acid-d6; 4-trans-Hydroxy-L-proline-d6; L-Hypro-d6; NSC 46704-d6;Alternate CAS #:unlabelled: 51-35-4Molecular Formula:C₅H₃D₆NO₃Molecular Weight:137.17Category:Building Blocks; Isotopic Labeled Analogues;Applications:trans-4-Hydroxy-L-proline-d9 is deuterium labelled trans-4-Hydroxy-L-proline (H952376). A natural constituent of animal structural proteins such as collagen and elastin. Several microorganisms producing proline trans-4- and cis-3-hydroxylase were discovered and these enzymes were applied to the industrial production of trans-4- […]