Chemical Name:Iloperidone 3,4-DehydropiperidineSynonyms:1-(4-(3-(4-(6-Fluorobenzo[d]isoxazol-3-yl)-5,6-dihydropyridin-1(2H)-yl)propoxy)-3-methoxyphenyl)ethanoneMolecular Formula:C₂₄H₂₅FN₂O₄Molecular Weight:424.46Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Iloperidone 3,4-Dehydropiperidine is an impurity of Iloperidone (I267200), a combined dopamine (D2) and serotonin (5HT2) receptor antagonist.References:Sainati, S.M., et al.: J. Clin. Pharmacol., 35, 713 (1995); Szewczak, M.R., et al.: J. Pharmacol. Exp. Ther., 274, 1404 (1995); Kongsamut, S., et al.: Eur. J. Pharmacol., 317, 417 (1996)To ensure […]
Juglanin
Chemical Name:JuglaninSynonyms:3-(Alpha-L-Arabinofuranosyloxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 5,7,4′-Trihydroxyflavone 3-alpha-L-arabinofuranoside; Euglanin; Kaempferol 3-O-arabinoside; Kaempferol 3-O-alpha-L-arabinofuranoside; Kaempferol 3-arabinoside; 3,4′,5,7-tetrahydroxyflavone 3-alpha-L-arabinofuranoside;CAS Number:5041-67-8Molecular Formula:C₂₀H₁₈O₁₀Molecular Weight:418.35Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Juglanin inhibits the proliferation of breast cancer cell in a dose- and time-dependent manner and presents less cytotoxic against the normal cells. It is a JNK activator.References:Sun, Z. L., et al.: Biomed Pharmacother., […]
(2E,4E)-5-(4-Hydroxy-2,6,6-trimethyl-1-cyclohexen-1-yl)-3-methyl-2,4-pentadienal
Chemical Name:(2E,4E)-5-(4-Hydroxy-2,6,6-trimethyl-1-cyclohexen-1-yl)-3-methyl-2,4-pentadienalCAS Number:535950-02-8Molecular Formula:C₁₅H₂₂O₂Molecular Weight:234.33Category:Building Blocks; Miscellaneous;Applications:(2E,4E)-5-(4-Hydroxy-2,6,6-trimethyl-1-cyclohexen-1-yl)-3-methyl-2,4-pentadienal is an intermediate used in the synthesis of rac-all-trans 3-Hydroxy Retinal (80%) (H953285).To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. […]
2-(3-(4-Hydroxy-3,5-diiodophenoxy)-2,4-diiodobenzamido)-3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)propanoic Acid, Amide-Bridged
Chemical Name:2-(3-(4-Hydroxy-3,5-diiodophenoxy)-2,4-diiodobenzamido)-3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)propanoic Acid, Amide-BridgedAlternate CAS #:Parent compound: 51-48-9Molecular Formula:C₂₈H₁₆I₇NO₇Molecular Weight:1366.76Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:2-(3-(4-Hydroxy-3,5-diiodophenoxy)-2,4-diiodobenzamido)-3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)propanoic Acid, Amide-Bridged is a Levothyroxine impurity of Thyroxine (T425600), which is one of the thyroid hormones involved in the maintenance of metabolic homeostasis. Thyroxine is deiodinated in peripheral tissues to the active metabolite, liothyronine, which has been used to treat hyperlipidemia.References:Post, A., […]
3-Hydroxymethylcholanthrene trans-7,8-Dihydrodiol
Chemical Name:3-Hydroxymethylcholanthrene trans-7,8-DihydrodiolSynonyms:(7R-trans)-1,2,7,8-Tetrahydro-3-(hydroxymethyl)-benz[j]aceanthrylene-7,8-diol (9CI)Alternate CAS #:177327-79-6 (R,R trans)Molecular Formula:C₂₁H₁₈O₃Molecular Weight:318.37Category:Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;Applications:3-Hydroxymethylcholanthrene trans-7,8-Dihydrodiol has been shown to be a metabolite of 3-Hydroxymethylcholanthrene (3-OHMC) when incubated with rat liver microsomes.References:Shou, M.; et al.: Drug Metab. Dispos, 24, 595 (1996)To ensure the stability of our products, the efficient express delivery service will be used. […]
3-Hydroxymethylcholanthrene trans-11,12-Dihydrodiol
Chemical Name:3-Hydroxymethylcholanthrene trans-11,12-DihydrodiolSynonyms:(11R-trans)-1,2,11,12-Tetrahydro-3-(hydroxymethyl)-benz[j]aceanthrylene-11,12-diol (9CI)Alternate CAS #:177327-81-0 (R,R, trans)Molecular Formula:C₂₁H₁₈O₃Molecular Weight:318.37Category:Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;Applications:3-Hydroxymethylcholanthrene trans-11,12-Dihydrodiol has been shown to be a metabolite of 3-Hydroxymethylcholanthrene (3-OHMC) when incubated with rat liver microsomes.References:Shou, M.; et al.: Drug Metab. Dispos, 24, 595 (1996)To ensure the stability of our products, the efficient express delivery service will be used. […]
1-Hydroxy-3-methylcholanthrene
Chemical Name:1-Hydroxy-3-methylcholanthreneSynonyms:1,2-Dihydro-3-methyl-benz[j]aceanthrylen-1-ol; 3-Methyl-1-cholanthrenol (7CI,8CI); 2-Dihydro-3-methylbenz[j]aceanthrylen-1-ol; 3-Methylcholanthren-1-olCAS Number:3342-98-1Alternate CAS #:Parent compound: 56-49-5Molecular Formula:C₂₁H₁₆OMolecular Weight:284.35Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:1-Hydroxy-3-methylcholanthrene is a major metabolite of 2-Methylcholanthrene and has been shown to exhibit carcinogenicity in rats at the site of injection, causing sarcomas in 42% of rats subjected to testing within 52 weeks of initial injection.References:Flesher, J.W.; et al.: Biochem. […]
2-Hydroxy-3-methylcholanthrene
Chemical Name:2-Hydroxy-3-methylcholanthreneSynonyms:3-Methyl-2-cholanthrenol (7CI, 8CI); 1,2-Dihydro-3-methylbenz[j]aceanthrylen-2-ol; 3-Methylcholanthren-2-olCAS Number:3308-64-3Alternate CAS #:Parent compound: 56-49-5Molecular Formula:C₂₁H₁₆OMolecular Weight:284.35Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:2-Hydroxy-3-methylcholanthrene is a metabolite of 3-Methylcholanthrene, which is formed by liver microsomes in rats. The metabolism of the racemic mixture of 2-Hydroxy-3-methylcholanthrene was found to be enantiospecific; the rate of metabolism of the R isomer is faster than that of […]
3-Hydroxymethylcholanthrene trans-9,10-Dihydrodiol
Chemical Name:3-Hydroxymethylcholanthrene trans-9,10-DihydrodiolSynonyms:(9S-trans)-1,2,9,10-Tetrahydro-3-(hydroxymethyl)-benz[j]aceanthrylene-9,10-diolAlternate CAS #:177472-67-2 (S,S, trans); 177327-80-9 (R,R, trans)Molecular Formula:C₂₁H₁₈O₃Molecular Weight:318.37Category:Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;Applications:3-Hydroxymethylcholanthrene trans-9,10-Dihydrodiol has been shown to be a metabolite of 3-Hydroxymethylcholanthrene (3-OHMC) when incubated with rat liver microsomes.References:Shou, M.; et al.: Drug Metab. Dispos, 24, 595 (1996)To ensure the stability of our products, the efficient express delivery service will […]
3-Hydroxymethylcholanthrene-1-one
Chemical Name:3-Hydroxymethylcholanthrene-1-oneSynonyms:3-(hydroxymethyl)-benz[j]aceanthrylen-1(2H)-one (9CI)CAS Number:177237-83-2Alternate CAS #:Parent compound: 56-49-5Molecular Formula:C₂₁H₁₄O₂Molecular Weight:298.33Category:Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;Applications:3-Hydroxymethylcholanthrene-1-one has been shown to be a metabolite of 3-Hydroxymethylcholanthrene (3-OHMC) when incubated with rat liver microsomes.References:Shou, M.; et al.: Drug Metab. Dispos, 24, 595 (1996)To ensure the stability of our products, the efficient express delivery service will be used. We […]