(+)-Loline Dihydrochloride

Chemical Name:(+)-Loline DihydrochlorideSynonyms:Loline Dihydrochloride; [2R-(2α,3α,3aβ,4α,6aβ)]-Hexahydro-N-methyl-2,4-methano-4H-furo[3,2-b]pyrrol-3-amine Dihydrochloride; (2R,3R,3aS,6aS)-Hexahydro-N-methyl-2,4-methano-4H-furo[3,2-b]pyrrol-3-amine Dihydrochloride;CAS Number:25161-92-6Alternate CAS #:Free Base: 25161-91-5Molecular Formula:C₈H₁₄N₂O • 2HClAppearance:OilMolecular Weight:154.21 + (36.46)Solubility:Methanol, WaterCategory:Standards; Chiral Molecules; Natural Products;Applications:(+)-Loline Dihydrochloride is an alkaloid isolated from fungal endophytes, an endosymbiont that lives within a plant. Loline alkaloids were found to provide protection of host plants from aphids herbivory and environmental stresses […]

(+)-Loline-d3 Dihydrochloride

Chemical Name:(+)-Loline-d3 DihydrochlorideSynonyms:Loline-d3 Dihydrochloride; [2R-(2α,3α,3aβ,4α,6aβ)]-Hexahydro-N-methyl-2,4-methano-4H-furo[3,2-b]pyrrol-3-amine-d3 Dihydrochloride; (2R,3R,3aS,6aS)-Hexahydro-N-methyl-2,4-methano-4H-furo[3,2-b]pyrrol-3-amine-d3Dihydrochloride;Alternate CAS #:Unlabelled: 25161-92-6Molecular Formula:C₈H₁₃D₃Cl₂N₂OAppearance:OilMolecular Weight:230.15Solubility:Methanol, WaterCategory:Building Blocks; Isotopic Labeled Analogues;Applications:(+)-Loline-d3 Dihydrochloride is an isotope labelled derivative Loline (I707255), an alkaloid isolated from fungal endophytes, an endosymbiont that lives within a plant. Loline alkaloids were found to provide protection of host plants from aphids herbivory and environmental stresses such […]

Isopentenyl Pyrophosphate-d5 Triammonium Salt

Chemical Name:Isopentenyl Pyrophosphate-d5 Triammonium SaltSynonyms:Diphosphoric Acid Mono(3-methyl-3-butenyl-d5) Ester Triammonium Salt; Triammonium 3-Methyl-3-butenyl-d5 Pyrophosphate;CAS Number:1246817-54-8Alternate CAS #:116057-53-5-unlabelledMolecular Formula:C₅H₁₆D₅N₃O₇P₂Molecular Weight:302.21Category:Building Blocks; Isotopic Labeled Analogues;Applications:Labelled Isopentenyl Pyrophosphate. Used for the preparation of antitumor agents phosphohalohydrins.References:Dhe-Paganon, S., et al.: Biochem., 33, 13355 (1994), Tanaka, Y., et al.: Nature, 375 155 (1995), Wesch, D., et al.: Eur. J. Immunol., 27, […]

Isopilocarpic Acid-d3 Sodium Salt

Chemical Name:Isopilocarpic Acid-d3 Sodium SaltSynonyms:[R-(R*,R*)]-α-Ethyl-β-(hydroxymethyl)-1-methyl-1H-imidazole-5-butanoic Acid-d3 Monosodium Salt; Isopilocarpinate-d3 Sodium Salt; Isopilocarpinic Acid-d3 Sodium Salt; (αR,βR)-α-Ethyl-β-(hydroxymethyl)-1-methyl-1H-imidazole-5-butanoic Acid-d3 Sodium Salt; 1,2-Seco-3-isopilocarpin-2-oic Acid-d3 Sodium Salt;Alternate CAS #:unlabelled salt: 101769-87-3Molecular Formula:C11H14D3N2NaO3Molecular Weight:251.27Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Labelled Isopilocarpic Acid. Isopilocarpic Acid is a degradation product of Pilocarpine (P441500).Not a dangerous good if item is equal to or […]

(S,S)-Iso Valganciclovir Hydrochloride

Chemical Name:(S,S)-Iso Valganciclovir HydrochlorideSynonyms:(2S)-3-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-L-valine 2-Hydroxypropyl Ester HydrochlorideCAS Number:1401562-13-7Alternate CAS #:Free amine: 1401661-94-6Molecular Formula:C₁₄H₂₃ClN₆O₅Molecular Weight:390.82Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:(S,S)-Iso Valganciclovir Hydrochloride is an impurity of Valganciclovir (V092000); a pro-drug of Ganciclovir used in the treatment of retro-virus.References:Acosta, E., et al.: Clin. Pharmacol. Ther., 81, 867 (2007);To ensure the stability of our products, the efficient express delivery service […]

Ivacaftor Carboxylic Acid N-Glucuronide

Chemical Name:Ivacaftor Carboxylic Acid N-GlucuronideMolecular Formula:C₃₀H₃₄N₂O₁₁Molecular Weight:598.6Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Ivacaftor Carboxylic Acid N-Glucuronide, is an impurity of Ivacaftor (I940600); a drug used in the treatment of cystic fibrosis.References:Clancy, J. et al.: Am. J. Resp. Crit. Care. Med., 186, 593 (2012)To ensure the stability of our products, the efficient express delivery service will be used. We […]

Ivacaftor Carboxylic Acid O-Glucuronide

Chemical Name:Ivacaftor Carboxylic Acid O-GlucuronideMolecular Formula:C₃₀H₃₄N₂O₁₁Molecular Weight:598.6Category:Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; Carbohydrates and Oligosaccharides;Applications:Ivacaftor Carboxylic Acid O-Glucuronide, is an impurity of Ivacaftor (I940600); a drug used in the treatment of cystic fibrosis.References:Clancy, J. et al.: Am. J. Resp. Crit. Care. Med., 186, 593 (2012)To ensure the stability of our products, the efficient express delivery […]

Ivacaftor Acyl-Glucuronide

Chemical Name:Ivacaftor Acyl-GlucuronideMolecular Formula:C₃₀H₃₄N₂O₁₀Molecular Weight:582.6Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Ivacaftor Acyl-Glucuronide, is an impurity of Tamoxifen (T006000), a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor.References:Sutherland, R., et al.: Nature, 267, 434 (1977), Lerner, L., et al.: Cancer Res., 50, 4177 (1990), Love, R., et al.: J. Clin. Oncol., 20 2559 (2002),To ensure […]

Ilepatril

Chemical Name:IlepatrilSynonyms:(4S,7S,12bR)-7-[[(2S)-2-(Acetylthio)-3-methyl-1-oxobutyl]amino]-1,2,3,4,6,7,8,12b-octahydro-6-oxo-pyrido[2,1-a][2]benzazepine-4-carboxylic Acid; AVE-7688;CAS Number:473289-62-2Molecular Formula:C₂₂H₂₈N₂O₅SMolecular Weight:432.53Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:A dual angiotensin-converting enzyme and neutral endopeptidase inhibitor, for the potential treatment of hypertension and diabetic nephropathy. Ilepatril is currently in phase IIb/III clinical trials for hypertension and phase II trials for diabetic nephropathy.References:Tabrizchi, R., et al.: Drugs, 63, 2185 (2003), Azizi, […]

Jasmolin I

Chemical Name:Jasmolin ISynonyms:(1R,3R)-2,2-Dimethyl-3-(2-methyl-1-propen-1-yl)cyclopropanecarboxylic Acid (1S)-2-Methyl-4-oxo-3-(2Z)-2-penten-1-yl-2-cyclopenten-1-yl Ester;CAS Number:4466-14-2Molecular Formula:C₂₁H₃₀O₃Appearance:LiquidMolecular Weight:330.46Category:Standards; Chiral Molecules; Environmental Standards, Mutagens and Metabolites; Pesticides; Natural Products;Applications:Jasmolin I is an active insecticidal constituent of pyrethrum flowers.Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageReferences:Okey, A., et al.: Pharmacol. Ther., 45, […]

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