Chemical Name:Imidafenacin-d13Synonyms:2-Methyl-α,α-diphenyl-1H-imidazole-1-butanamide-d13; 4-(2-Methyl-1-imidazolyl)-2,2-diphenylbutanamide-d13; 4-(2-Methyl-1H-imidazol-1-yl)-2,2-diphenylbutanamide-d13; Imidafenacin-d13; KRP 197-d13; Uritos-d13;Alternate CAS #:Unlabelled: 170105-16-5Molecular Formula:C₂₀H₈D₁₃N₃OMolecular Weight:332.48Category:Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Imidafenacin-d13 is deutirium labelled imidafenacin which is a novel therapeutic agent for overactive bladder with antimuscarinic activity, on mediator release from urothelium and detrusor overactivity induced by cerebral infarction.References:Andersson, K., et al.: Eur. […]

Chemical Name:JQEZ5Synonyms:N-[(1,2-Dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[6-(4-methyl-1-piperazinyl)-3-pyridinyl]-1H-pyrazolo[3,4-b]pyridine-4-carboxamideCAS Number:1913252-04-6Molecular Formula:C₃₀H₃₈N₈O₂Molecular Weight:542.68Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:JQEZ5, is a novel and potent EZH2 inhibitor.References:Xhang H. et al.: Cancer Discov. 2016 Sep;6(9):1006-21.;To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of […]

Chemical Name:3-Imidazo[1,2-a]pyridin-3-yl-4-[1,2,3,4-tetrahydro-2-(1-piperidinylcarbonyl)pyrrolo[3,2,1-jk][1,4]benzodiazepin-7-yl]-1H-pyrrole-2,5-dioneSynonyms:7-(2,5-Dihydro-4-imidazo[1,2-a]pyridin-3-yl-2,5-dioxo-1H-pyrrol-3-yl)-1,2,3,4-tetrahydro-2-(1-piperidinylcarbonyl)pyrrolo[3,2,1-jk][1,4]benzodiazepine; LY2090314CAS Number:603281-60-3Molecular Formula:C28H26N6O3Molecular Weight:494.6Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:3-Imidazo[1,2-a]pyridin-3-yl-4-[1,2,3,4-tetrahydro-2-(1-piperidinylcarbonyl)pyrrolo[3,2,1-jk][1,4]benzodiazepin-7-yl]-1H-pyrrole-2,5-dione is a newly developed potent and selective biarylmaleimide GSK3 inhibitor which may be effective in lowering plasma glucose in type 2 diabetes.References:Engler, T.A.. et al.: Bioorg. Med. Chem. Lett., 15, 899 (2005); Engler, T.A., et al.: J. Med. Chem., 47, 3934 (2004); Dessalew, N., et al.: […]

Chemical Name:JNJ 10397049Synonyms:N-(2,4-Dibromophenyl)-N’-[(4S,5S)-2,2-dimethyl-4-phenyl-1,3-dioxan-5-yl]-urea; 1-(2,4-Dibromophenyl)-3-((4S,5S)-2,2-dimethyl-4-phenyl-[1,3]dioxan-5-yl)urea;CAS Number:708275-58-5Molecular Formula:C₁₉H₂₀Br₂N₂O₃Molecular Weight:484.18Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:JNJ 10397049 is a selective OX2 receptor antagonist that exhibited sleep promoting effects in rats.References:Faedo, S., et al.: Euro. J. Pharmacol., 692, 1 (2012); Heifetz, A., et al.: Biochem., 51, 3178 (2012); Dugovic, C., et al.: J. Pharmacol. Exp. Therap., 330, 142 (2009);To ensure the stability […]

Chemical Name:1H-Imidazole-4,5-13C2-15N2CAS Number:NAMolecular Formula:C13C2H415N2Molecular Weight:72.05Applications:1H-Imidazole-4,5-13C2-15N2 is a useful research chemical.To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be wrapped with dried […]

Chemical Name:Indacaterol-d10Alternate CAS #:312753-06-3Molecular Formula:C₂₄H₁₈D₁₀N₂O₃Molecular Weight:402.55Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:A labeled Indacaterol (I499745) which is a β-adrenoreceptor agonists for treatment of asthma and bronchodilator treatment for patients with chronic obstructive pulmonary diseases.References:Crisafulli, E., et al.; Expert Opinion Pharmacother., 18, 1499 (2017); Aparici, M., et al.: Pul. Pharmacol. Ther., 46, 1 (2017); Demin, I., et al.: Int. […]

Chemical Name:Inarigivir SoproxilSynonyms:2′-O-Methyl-P(S)-[[[(1-methylethoxy)carbonyl]oxy]methyl]-P-thiouridylyl-(3’→5′)-2′-deoxyadenosine; SB 44 (dinucleotide); SB 9200CAS Number:942123-43-5Molecular Formula:C₂₅H₃₄N₇O₁₃PSMolecular Weight:703.62Category:Standards; Anti-virals/Anti-retrovirals;Applications:Inarigivir soproxil, has a broad-spectrum antiviral activity against RNA viruses including hepatitis C virus (HCV), norovirus, respiratory syncytial virus and influenza and has demonstrated activity against hepatitis B virus (HBV) in vitro and in vivo.References:Coughlin, J. et al.: Bioorg. Med. Chem. Lett. Vol.20, Issue.5 […]

Chemical Name:Intermedine N-OxideSynonyms:(2S,3R)-2,3-Dihydroxy-2-(1-methylethyl)butanoic Acid [(1R,7aR)-2,3,5,7a-Tetrahydro-1-hydroxy-4-oxido-1H-pyrrolizin-7-yl]methyl Ester; [1R-[1α,7(2S*,3R*),7aβ]]-2,3-Dihydroxy-2-(1-methylethyl)butanoic Acid (2,3,5,7a-Tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl)methyl Ester N-Oxide; [1R-[1α,7(2S*,3R*),7aβ]]-2,3-Dihydroxy-2-(1-methylethyl)butanoic Acid (2,3,5,7a-Tetrahydro-1-hydroxy-4-oxido-1H-pyrrolizin-7-yl)methyl EsterCAS Number:95462-14-9Molecular Formula:C₁₅H₂₅NO₆Molecular Weight:315.36Category:Building Blocks;Applications:Intermedine N-oxide is a pyrrolizidine alkaloid that is isolated from Cerinthe glabra, a flower plant that grows in alpine areas. Intermedine N-oxide is also a potential anticancer agent.References:Bittmann, F.: Veg. Hist. Arch., 16, 139 (2007); Luber, M., […]

Chemical Name:(+)-Loline DihydrochlorideSynonyms:Loline Dihydrochloride; [2R-(2α,3α,3aβ,4α,6aβ)]-Hexahydro-N-methyl-2,4-methano-4H-furo[3,2-b]pyrrol-3-amine Dihydrochloride; (2R,3R,3aS,6aS)-Hexahydro-N-methyl-2,4-methano-4H-furo[3,2-b]pyrrol-3-amine Dihydrochloride;CAS Number:25161-92-6Alternate CAS #:Free Base: 25161-91-5Molecular Formula:C₈H₁₄N₂O • 2HClAppearance:OilMolecular Weight:154.21 + (36.46)Solubility:Methanol, WaterCategory:Standards; Chiral Molecules; Natural Products;Applications:(+)-Loline Dihydrochloride is an alkaloid isolated from fungal endophytes, an endosymbiont that lives within a plant. Loline alkaloids were found to provide protection of host plants from aphids herbivory and environmental stresses […]

Chemical Name:(+)-Loline-d3 DihydrochlorideSynonyms:Loline-d3 Dihydrochloride; [2R-(2α,3α,3aβ,4α,6aβ)]-Hexahydro-N-methyl-2,4-methano-4H-furo[3,2-b]pyrrol-3-amine-d3 Dihydrochloride; (2R,3R,3aS,6aS)-Hexahydro-N-methyl-2,4-methano-4H-furo[3,2-b]pyrrol-3-amine-d3Dihydrochloride;Alternate CAS #:Unlabelled: 25161-92-6Molecular Formula:C₈H₁₃D₃Cl₂N₂OAppearance:OilMolecular Weight:230.15Solubility:Methanol, WaterCategory:Building Blocks; Isotopic Labeled Analogues;Applications:(+)-Loline-d3 Dihydrochloride is an isotope labelled derivative Loline (I707255), an alkaloid isolated from fungal endophytes, an endosymbiont that lives within a plant. Loline alkaloids were found to provide protection of host plants from aphids herbivory and environmental stresses such […]