Chemical Name:8-epi LubiprostoneMolecular Formula:C₂₀H₃₂F₂O₅Molecular Weight:390.46Category:Building Blocks; Miscellaneous;Applications:8-epi Lubiprostone is an analog of Lubiprostone (L473500). Lubiprostone is a bicyclic fatty acid metabolite analog of Prostaglandin E1. It activates specific chloride channels in the gastrointestinal tract to stimulate intestinal fluid secretion, increase gastrointestinal transit, and improve symptoms of constipation.References:Farthing, M., et al.: Drugs, 56, 11 (1998), Pare, […]

Chemical Name:K777 HydrochlorideSynonyms:4-Methyl-N-[(1S)-2-oxo-2-[[(1S,2E)-1-(2-phenylethyl)-3-(phenylsulfonyl)-2-propenyl]amino]-1-(phenylmethyl)ethyl]-1-piperazinecarboxamide Monohydrochloride; PC 3316 Hydrochloride;CAS Number:502960-92-1Alternate CAS #:502960-90-9Molecular Formula:C₃₂H₃₈N₄O₄S • HClMolecular Weight:574.73 + 36.46Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:K777 Hydrochloride acts as a cathespin B inhibitor which may be useful in the therapeutic treatment of Chagas’ disease.References:Lee, G. et al.: Biochem., 51, 10087 (2012);To ensure the stability of our products, the […]

Chemical Name:12-epi LubiprostoneMolecular Formula:C₂₀H₃₂F₂O₅Category:Building Blocks; Miscellaneous;Applications:12-epi Lubiprostone is an analog of Lubiprostone (L473500). Lubiprostone is a bicyclic fatty acid metabolite analog of Prostaglandin E1. It activates specific chloride channels in the gastrointestinal tract to stimulate intestinal fluid secretion, increase gastrointestinal transit, and improve symptoms of constipation.References:Farthing, M., et al.: Drugs, 56, 11 (1998), Pare, P., […]

Chemical Name:1-Keto-3-methylcholanthreneSynonyms:3-Methyl-benz[j]aceanthrylen-1(2H)-one; 3-Methyl-1-cholanthrenone (7CI, 8CI); 3-Methylbenz[j]aceanthrylen-1(2H)-one; 1-Oxo-3-methylcholanthrene; 3-Methyl-1-oxocholanthrene; 3-Methylcholanthren-1-oneCAS Number:3343-07-5Alternate CAS #:Parent compound: 56-49-5Molecular Formula:C₂₁H₁₄OMolecular Weight:282.34Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:1-Keto-3-methylcholanthrene is a product of the one electron oxidation of 3-Methylcholanthrene and is also present in mammalian metabolism as a carcinogen.References:Lehner, A.F.; et al.: J. Molec. Struc, 1137, 67 (2017)To ensure the stability of our products, the […]

Chemical Name:11-epi LubiprostoneMolecular Formula:C₂₀H₃₂F₂O₅Molecular Weight:390.46Category:Building Blocks; Miscellaneous;Applications:11-epi Lubiprostone is an analog of Lubiprotone (L473500). Lubiprostone is a bicyclic fatty acid metabolite analog of Prostaglandin E1. It activates specific chloride channels in the gastrointestinal tract to stimulate intestinal fluid secretion, increase gastrointestinal transit, and improve symptoms of constipation.References:Farthing, M., et al.: Drugs, 56, 11 (1998), Pare, […]

Chemical Name:Kresoxim-Methyl-d3Synonyms:(αE)-α-(Methoxyimino)-2-[(2-methylphenoxy)methyl]benzeneacetic Acid Methyl Ester-d3; BAS 490-02F-d3; BAS 490F-d3; Candit-d3; Cygnus-d3; Discus-d3; Discus (fungicide)-d3; RIL-FA 200-d3; Strob 1-d3; Stroby-d3; Stroby WG-d3Alternate CAS #:143390-89-0Molecular Formula:C₁₈H₁₆D₃NO₄Molecular Weight:316.37Category:Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Kresoxim-Methyl-d3 is the labeled analogue of Kresoxim-methyl (K659000), which is an agricultural fungicide.References:Gold, R.E. et al.: Pestic. Sci., 43, 250 (1995); […]

Chemical Name:Lucifer Yellow VS Dilithium SaltSynonyms:6-Amino-2-[3-(ethenylsulfonyl)phenyl]-2,3-dihydro-1,3-dioxo-1H-benz[de]isoquinoline-5,8-disulfonic Acid Dilithium SaltCAS Number:71231-14-6Alternate CAS #:Free Base: 107014-64-2Molecular Formula:C₂₀H₁₄N₂O₁₀S₃ •2LiMolecular Weight:538.53+2(6.94)Category:Research Tools; Materials; Dyes;Applications:Lucifer Yellow VS Dilithium Salt is a highly fluorescent dye used for labeling proteins. It can also be used in analytical study of dual analyte flow injection fluorescence immunoassays using thiophilic gel reactors and synchronous scanning […]

Chemical Name:KRP-203-d5Synonyms:2-Amino-2-(2-chloro-4-((3-((phenyl-d5)methoxy)phenyl)thio)phenethyl)propane-1,3-diol;Alternate CAS #:509088-69-1Molecular Formula:C₂₄H₂₁D₅ClNO₃SMolecular Weight:449.02Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;Applications:KRP-203-d5 is a labelled analogue of KRP-203 (K660300), which is a novel sphingosine-1-phosphate receptor agonists in the treatment of autoimmune diseases. Immunosuppressant.References:Yanagawa, Y., et al.: J. Immunol., 160, 5493 (1998), Takahashi, M., et al.: Cardiovasc. Res., 52, 438 (2001), Liu, G., et al.: J. […]

Chemical Name:LY 3009120Synonyms:N-(3,3-Dimethylbutyl)-N’-[2-fluoro-4-methyl-5-[7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl]phenyl]urea;CAS Number:1454682-72-4Molecular Formula:C₂₃H₂₉FN₆OMolecular Weight:424.51Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:LY 3009120 is a potent pan-Rad inhibitor used in the inhibition of tumors. Dose-dependant inhibition.References:Henry, J. et al.: J. Med. Chem., 58, 4165 (2015);To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped […]

Chemical Name:KU-60019Synonyms:2-((2R,6S)-2,6-Dimethylmorpholino)-N-(5-(6-morpholino-4-oxo-4H-pyran-2-yl)-9H-thioxanthen-2-yl)acetamideCAS Number:925701-46-8Alternate CAS #:Deleted: 925701-49-1, 894104-72-4Molecular Formula:C₃₀H₃₃N₃O₅SMolecular Weight:547.67Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:KU-60019 is a potent and reversible inhibitor of ATM kinase, blocking the phosphorylation of ATM substrate proteins. It sensitizes glioma cells to radiation and inhibits migration and invasion of glioma cells in vitro.References:Golding, S. et al.: Mol. Cancer Ther., 8, 2894 (2009); Golding, S. […]