Melphalan Dimer-d8 Dihydrochloride

Chemical Name:Melphalan Dimer-d8 DihydrochlorideSynonyms:4-[[2-[[4-[Bis(2-chloroethyl)amino]-L-phenylalanyl]oxy]ethyl](2-chloroethyl)amino]-L-phenylalanine-d8 DihydrochlorideCAS Number:1801709-41-0Alternate CAS #:M216905 Unlabelled free base (no cas#)Molecular Formula:C₂₆H₂₉D₈Cl₅N₄O₄Molecular Weight:654.91Category:Building Blocks; Isotopic Labeled Analogues;Applications:Labelled Melphalan Dimer (M216905) which is an impurity from the synthesis of Melphanan (M216900) an antineoplastic.References:Ross, W.C.J., et al.: Biochem. Pharmacol., 13, 969 (1964); Donelli, M.G., et al.: J. Pharm. Pharmacol., 18, 760 (1966); Furner, R.L., et […]

Menadione sodium bisulfite hydrate-13C6

Chemical Name:Menadione sodium bisulfite hydrate-13C6CAS Number:N/AMolecular Formula:C513C6H9NaO5S•xH₂OApplications:Menadione sodium bisulfite hydrate-13C6 is a useful research chemical.To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products […]

1-Keto-3-methylcholanthrene

Chemical Name:1-Keto-3-methylcholanthreneSynonyms:3-Methyl-benz[j]aceanthrylen-1(2H)-one; 3-Methyl-1-cholanthrenone (7CI, 8CI); 3-Methylbenz[j]aceanthrylen-1(2H)-one; 1-Oxo-3-methylcholanthrene; 3-Methyl-1-oxocholanthrene; 3-Methylcholanthren-1-oneCAS Number:3343-07-5Alternate CAS #:Parent compound: 56-49-5Molecular Formula:C₂₁H₁₄OMolecular Weight:282.34Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:1-Keto-3-methylcholanthrene is a product of the one electron oxidation of 3-Methylcholanthrene and is also present in mammalian metabolism as a carcinogen.References:Lehner, A.F.; et al.: J. Molec. Struc, 1137, 67 (2017)To ensure the stability of our products, the […]

11-epi Lubiprostone

Chemical Name:11-epi LubiprostoneMolecular Formula:C₂₀H₃₂F₂O₅Molecular Weight:390.46Category:Building Blocks; Miscellaneous;Applications:11-epi Lubiprostone is an analog of Lubiprotone (L473500). Lubiprostone is a bicyclic fatty acid metabolite analog of Prostaglandin E1. It activates specific chloride channels in the gastrointestinal tract to stimulate intestinal fluid secretion, increase gastrointestinal transit, and improve symptoms of constipation.References:Farthing, M., et al.: Drugs, 56, 11 (1998), Pare, […]

Kresoxim-Methyl-d3

Chemical Name:Kresoxim-Methyl-d3Synonyms:(αE)-α-(Methoxyimino)-2-[(2-methylphenoxy)methyl]benzeneacetic Acid Methyl Ester-d3; BAS 490-02F-d3; BAS 490F-d3; Candit-d3; Cygnus-d3; Discus-d3; Discus (fungicide)-d3; RIL-FA 200-d3; Strob 1-d3; Stroby-d3; Stroby WG-d3Alternate CAS #:143390-89-0Molecular Formula:C₁₈H₁₆D₃NO₄Molecular Weight:316.37Category:Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Kresoxim-Methyl-d3 is the labeled analogue of Kresoxim-methyl (K659000), which is an agricultural fungicide.References:Gold, R.E. et al.: Pestic. Sci., 43, 250 (1995); […]

Lucifer Yellow VS Dilithium Salt

Chemical Name:Lucifer Yellow VS Dilithium SaltSynonyms:6-Amino-2-[3-(ethenylsulfonyl)phenyl]-2,3-dihydro-1,3-dioxo-1H-benz[de]isoquinoline-5,8-disulfonic Acid Dilithium SaltCAS Number:71231-14-6Alternate CAS #:Free Base: 107014-64-2Molecular Formula:C₂₀H₁₄N₂O₁₀S₃ •2LiMolecular Weight:538.53+2(6.94)Category:Research Tools; Materials; Dyes;Applications:Lucifer Yellow VS Dilithium Salt is a highly fluorescent dye used for labeling proteins. It can also be used in analytical study of dual analyte flow injection fluorescence immunoassays using thiophilic gel reactors and synchronous scanning […]

KRP-203-d5

Chemical Name:KRP-203-d5Synonyms:2-Amino-2-(2-chloro-4-((3-((phenyl-d5)methoxy)phenyl)thio)phenethyl)propane-1,3-diol;Alternate CAS #:509088-69-1Molecular Formula:C₂₄H₂₁D₅ClNO₃SMolecular Weight:449.02Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;Applications:KRP-203-d5 is a labelled analogue of KRP-203 (K660300), which is a novel sphingosine-1-phosphate receptor agonists in the treatment of autoimmune diseases. Immunosuppressant.References:Yanagawa, Y., et al.: J. Immunol., 160, 5493 (1998), Takahashi, M., et al.: Cardiovasc. Res., 52, 438 (2001), Liu, G., et al.: J. […]

LY 3009120

Chemical Name:LY 3009120Synonyms:N-(3,3-Dimethylbutyl)-N’-[2-fluoro-4-methyl-5-[7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl]phenyl]urea;CAS Number:1454682-72-4Molecular Formula:C₂₃H₂₉FN₆OMolecular Weight:424.51Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:LY 3009120 is a potent pan-Rad inhibitor used in the inhibition of tumors. Dose-dependant inhibition.References:Henry, J. et al.: J. Med. Chem., 58, 4165 (2015);To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped […]

KU-60019

Chemical Name:KU-60019Synonyms:2-((2R,6S)-2,6-Dimethylmorpholino)-N-(5-(6-morpholino-4-oxo-4H-pyran-2-yl)-9H-thioxanthen-2-yl)acetamideCAS Number:925701-46-8Alternate CAS #:Deleted: 925701-49-1, 894104-72-4Molecular Formula:C₃₀H₃₃N₃O₅SMolecular Weight:547.67Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:KU-60019 is a potent and reversible inhibitor of ATM kinase, blocking the phosphorylation of ATM substrate proteins. It sensitizes glioma cells to radiation and inhibits migration and invasion of glioma cells in vitro.References:Golding, S. et al.: Mol. Cancer Ther., 8, 2894 (2009); Golding, S. […]

rac trans-Lafutidine

Chemical Name:rac trans-LafutidineSynonyms:2-[(2-Furanylmethyl)sulfinyl]-N-[(2E)-4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-2-buten-1-yl]acetamide;CAS Number:206449-94-7Molecular Formula:C22H29N3O4SMolecular Weight:431.55Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:A trans isomeric impurity of rac Lafutidine (L168500).References:Onodera, S., et al.: Jpn. J. Pharmacol., 68, 161 (1995); Umeda, M., et al.: J. Gastroenterol. Heoatol., 14, 859 (1999); Ajioka, H., et al.: Pharmacology, 61, 83 (2000);To ensure the stability of our products, the efficient express delivery service will […]

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