Chemical Name:β-Muricholic Acid Glucuronide Conjugate 2Synonyms:(2S,3S,4S,5R,6R)-6-(((3R,5R,6S,7R,8S,9S,10R,13R,14S,17R)-17-((R)-4-Carboxybutan-2-yl)-3,6-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic AcidAlternate CAS #:2393-59-1Molecular Formula:C₃₀H₄₈O₁₁Molecular Weight:584.7Category:Standards; Steroids; Pharmaceutical/API Drug Impurities/Metabolites;Applications:β-Muricholic Acid Glucuronide Conjugate 2 is a related compound of β-Muricholic Acid (M732755), a bile acid found in urine. β-Muricholic Acid has been used in studies of down regulation of transporter protein through ubiquitin dependent protein degradation.References:Miyata, M., et al.: Euro. […]

Chemical Name:Trazodone-3,3’-DimerSynonyms:2,2′-((4,4′-(Ethane-1,1-diylbis(2-chloro-3,1-phenylene))bis(piperazine-4,1-diyl))bis(propane-3,1-diyl))bis([1,2,4]triazolo[4,3-a]pyridin-3(2H)-one)Molecular Formula:C₄₀H₄₆Cl₂N₁₀O₂Molecular Weight:769.77Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Trazodone-3,3’-Dimer is a Trazodone Hydrochloride (T718500) impurity, which can be synthesized from 2-Chloro-3-nitrobenzoic Acid (C374075).To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against […]

Chemical Name:LY 311727Synonyms:P-[3-[[3-(2-Amino-2-oxoethyl)-2-ethyl-1-(phenylmethyl)-1H-indol-5-yl]oxy]propyl]phosphonic Acid; [3-[[3-(2-Amino-2-oxoethyl)-2-ethyl-1-(phenylmethyl)-1H-indol-5-yl]oxy]propyl]phosphonic Acid; [3-[[3-(Amidomethyl)-2-ethyl-1-(phenylmethyl)indol-5-yl]oxy]propyl]phosphonic AcidCAS Number:164083-84-5Molecular Formula:C₂₂H₂₇N₂O₅PMolecular Weight:430.43Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:LY 311727 is an inhibitor of secretory phospholipase A2 (sPLA2) and can be used to block Pseudomonas aeruginosa cytotoxicity. It can also attenuate VEGF-mediated platelet-activating factor (PAF) synthesis in HUVEC and BAEC cells.References:Phillips, R., et al.: J. Biol. […]

Chemical Name:4,4′-Methyl-methylene Trazodone Dimer-d12Molecular Formula:C₄₀H₃₄D₁₂Cl₂N₁₀O₂Molecular Weight:781.84Category:Standards; Isotopic Labeled Analogues;Applications:4,4′-Methyl-methylene Trazodone Dimer-d12 is an isotopic analog of the impurity 4,4′-Methyl-methylene Trazodone Dimer (M260210).To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them […]

Chemical Name:LY2562175Synonyms:6-[4-[[5-Cyclopropyl-3-(2,6-dichlorophenyl)-4-isoxazolyl]methoxy]-1-piperidinyl]-1-methyl-1H-indole-3-carboxylic Acid; LY-2562175CAS Number:1103500-20-4Molecular Formula:C₂₈H₂₇Cl₂N₃O₄Molecular Weight:540.44Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:LY2562175, is a potent and selective FXR agonist with an EC50 of 193 nM.References:Genin, M. J. et al.: J. Med. Chem., 58, 9768 (2015).To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be […]

Chemical Name:(7R)-MethopreneSynonyms:[R-(E,E)]-11-Methoxy-3,7,11-trimethyl-2,4-dodecadienoic Acid 1-Methylethyl Ester; ZR 1020CAS Number:65733-17-7Molecular Formula:C₁₉H₃₄O₃Molecular Weight:310.47Category:Standards; Chiral Molecules; Environmental Standards, Mutagens and Metabolites;Applications:(7R)-Methoprene is used in the insect growth regulators (IGR’s) with juvenile hormone activity.Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageReferences:Henrick, C. A., et al.: J. […]

Chemical Name:LumateperoneSynonyms:1-(4-fluorophenyl)-4-[(6bR,10aS)-3-methyl-2,3,6b,9,10,10a-hexahydro-11H-pyrido[3′,4′:4,5]pyrrolo[1,2,3-de]quinoxalin-8(7H)-yl]butan-1-one; ITI 007; 1-(4-Fluorophenyl)-4-[(6bR,10aS)-2,3,6b,9,10,10a-hexahydro-3-methyl-1H-pyrido[3′,4′:4,5]pyrrolo[1,2,3-de]quinoxalin-8(7H)-yl]-1-butanoneCAS Number:313368-91-1Molecular Formula:C₂₄H₂₈FN₃OAppearance:Light Brown to Brown Thick OilMolecular Weight:393.5Solubility:DMSO (Slightly), Methanol (Very Slightly)Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Lumateperone was a drug developed for the treatment of schizophrenia. May have applications in bipolar depression.References:Corponi, F., et al.: Eur. Neuropsychopharmacol., 29, 971-985 (2019)To ensure the stability of our products, the efficient express delivery service will […]

Chemical Name:Cis-Asenapine Fumaric AcidSynonyms:(3aS,12bS)-2-Methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrol-5-amine FumarateCAS Number:1688678-60-5Molecular Formula:C₁₇H₁₈N₂O • (C₄H₄O₄)Molecular Weight:266.34 + (116.07)Category:Building Blocks; Miscellaneous;Applications:iCis-Asenapine Fumaric Acid 1s an analogue of Asenapine (A788000). Asenapine (A788000) is combined serotonin (5HT2) and dopamine (D2) receptor antagonist; structurally related to Mianserin. Antipsychotic.Asenapine pyrrole fumarateReferences:Meltzer, H., et al.: J. Pharmacol. Exp. Ther., 251, 238 (1989);Schotte, A., et al.: Brain Res., […]

Chemical Name:LY3295668Synonyms:(2R,4R)-1-[(3-Chloro-2-fluorophenyl)methyl]-4-[[3-fluoro-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyridinyl]methyl]-2-methyl-4-piperidinecarboxylic Acid;CAS Number:1919888-06-4Molecular Formula:C₂₄H₂₆ClF₂N₅O₂Molecular Weight:489.95Category:Research Tools; Molecular Biology; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:LY3295668 is a potent, orally active and highly specific Aurora-A kinase inhibitor.References:Cheng, D., et al.: From PCT Int. Appl. (2021), WO 2021147974 A1 20210729To ensure the stability of our products, the efficient express delivery service will be used. We also […]

Chemical Name:4′-Methoxy-N,N-dimethyl-3′-[[[3-[[2-[(3-methylbenzoyl)amino]ethyl]amino]phenyl]amino]sulfonyl]-[1,1′-biphenyl]-3-carboxamideSynonyms:Orexin 2 Receptor AgonistCAS Number:1796565-52-0Molecular Formula:C₃₂H₃₄N₄O₅SMolecular Weight:586.7Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:4′-Methoxy-N,N-dimethyl-3′-[[[3-[[2-[(3-methylbenzoyl)amino]ethyl]amino]phenyl]amino]sulfonyl]-[1,1′-biphenyl]-3-carboxamide is an intermediate used to prepare sulfonamide derivatives as orexin receptor agonist for treatment of narcolepsy.References:Nagase, H., et al.: PCT Int. Appl., WO 2015088000 A1 20150618 (2015)To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will […]