Methyl (2E)-3-ethyl-5-[(2R,3S)-3-ethyl-3-methyl-2-oxiranyl]-2-pentenoate

Chemical Name:Methyl (2E)-3-ethyl-5-[(2R,3S)-3-ethyl-3-methyl-2-oxiranyl]-2-pentenoateSynonyms:rac-Methyl (E)-3-ethyl-5-((2R,3S)-3-ethyl-3-methyloxiran-2-yl)pent-2-enoateCAS Number:1389395-04-3Molecular Formula:C₁₃H₂₂O₃Molecular Weight:226.32Category:Building Blocks; Molecular Biology;Applications:Methyl (2E)-3-ethyl-5-[(2R,3S)-3-ethyl-3-methyl-2-oxiranyl]-2-pentenoate is an intermediate in the synthesis of Juvenile Hormone I (J211195), an acyclic sesquiterpenoid that regulates many aspects of insect physiology. Juvenile Hormone regulate development, reproduction, diapause, and polyphenisms.References:Riddiford, L.: Adv. Insect Physiol., 24, 213 (1994); Wyatt, G., Davey, K.: Adv. Insect Physiol., 26, […]

Methyl 1-Methoxy-4-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl]cyclohexanecarboxylate

Chemical Name:Methyl 1-Methoxy-4-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl]cyclohexanecarboxylateSynonyms:Cyclohexanecarboxyli​c acid, 1-​methoxy-​4-​[4-​methyl-​6-​[(5-​methyl-​1H-​pyrazol-​3-​yl)​amino]​-​2-​pyrimidinyl]​-​, methyl esterCAS Number:2097133-32-7Molecular Formula:C₁₈H₂₅N₅O₃Molecular Weight:359.42Category:Building Blocks; Molecular Biology;Applications:Methyl 1-Methoxy-4-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl]cyclohexanecarboxylate may be useful in the preparation of targeted antitumor medicine BLU-667 (pralsetinib).References:Liu, Y., et al.: Faming Zhuanli Shenqing, 12pp., CN 113072541 (2021)To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the […]

Melphalan Dimer-d8 Dihydrochloride

Chemical Name:Melphalan Dimer-d8 DihydrochlorideSynonyms:4-[[2-[[4-[Bis(2-chloroethyl)amino]-L-phenylalanyl]oxy]ethyl](2-chloroethyl)amino]-L-phenylalanine-d8 DihydrochlorideCAS Number:1801709-41-0Alternate CAS #:M216905 Unlabelled free base (no cas#)Molecular Formula:C₂₆H₂₉D₈Cl₅N₄O₄Molecular Weight:654.91Category:Building Blocks; Isotopic Labeled Analogues;Applications:Labelled Melphalan Dimer (M216905) which is an impurity from the synthesis of Melphanan (M216900) an antineoplastic.References:Ross, W.C.J., et al.: Biochem. Pharmacol., 13, 969 (1964); Donelli, M.G., et al.: J. Pharm. Pharmacol., 18, 760 (1966); Furner, R.L., et […]

Menadione sodium bisulfite hydrate-13C6

Chemical Name:Menadione sodium bisulfite hydrate-13C6CAS Number:N/AMolecular Formula:C513C6H9NaO5S•xH₂OApplications:Menadione sodium bisulfite hydrate-13C6 is a useful research chemical.To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products […]

Methyl 2-(Acetylamino)-6-amino-2,3,6-trideoxy-α-D-ribo-hexopyranoside Acetate

Chemical Name:Methyl 2-(Acetylamino)-6-amino-2,3,6-trideoxy-α-D-ribo-hexopyranoside AcetateAlternate CAS #:111170-71-9Molecular Formula:C₉H₁₈N₂O₄ • C ₂H₄O₂Molecular Weight:218.25 + 60.05Category:Standards; Carbohydrates and Oligosaccharides;Applications:Methyl 2-(Acetylamino)-6-amino-2,3,6-trideoxy-α-D-ribo-hexopyranoside Acetate is an intermediate used in the synthesis of 2,6-Diamino-2,3,6-trideoxy-D-ribo-Hexose Dihydrochloride (D416795), which is a degradent of Tobramycin (T524000) a single factor antibiotic comprising about 10% of nebramycin, the aminoglycosidic antibiotic complex produced by Streptomyces tenebrarius. Antibacterial.References:Koch, K.F., […]

β-Muricholic Acid Glucuronide Conjugate 2

Chemical Name:β-Muricholic Acid Glucuronide Conjugate 2Synonyms:(2S,3S,4S,5R,6R)-6-(((3R,5R,6S,7R,8S,9S,10R,13R,14S,17R)-17-((R)-4-Carboxybutan-2-yl)-3,6-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic AcidAlternate CAS #:2393-59-1Molecular Formula:C₃₀H₄₈O₁₁Molecular Weight:584.7Category:Standards; Steroids; Pharmaceutical/API Drug Impurities/Metabolites;Applications:β-Muricholic Acid Glucuronide Conjugate 2 is a related compound of β-Muricholic Acid (M732755), a bile acid found in urine. β-Muricholic Acid has been used in studies of down regulation of transporter protein through ubiquitin dependent protein degradation.References:Miyata, M., et al.: Euro. […]

Trazodone-3,3’-Dimer

Chemical Name:Trazodone-3,3’-DimerSynonyms:2,2′-((4,4′-(Ethane-1,1-diylbis(2-chloro-3,1-phenylene))bis(piperazine-4,1-diyl))bis(propane-3,1-diyl))bis([1,2,4]triazolo[4,3-a]pyridin-3(2H)-one)Molecular Formula:C₄₀H₄₆Cl₂N₁₀O₂Molecular Weight:769.77Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Trazodone-3,3’-Dimer is a Trazodone Hydrochloride (T718500) impurity, which can be synthesized from 2-Chloro-3-nitrobenzoic Acid (C374075).To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against […]

LY 311727

Chemical Name:LY 311727Synonyms:P-[3-[[3-(2-Amino-2-oxoethyl)-2-ethyl-1-(phenylmethyl)-1H-indol-5-yl]oxy]propyl]phosphonic Acid; [3-[[3-(2-Amino-2-oxoethyl)-2-ethyl-1-(phenylmethyl)-1H-indol-5-yl]oxy]propyl]phosphonic Acid; [3-[[3-(Amidomethyl)-2-ethyl-1-(phenylmethyl)indol-5-yl]oxy]propyl]phosphonic AcidCAS Number:164083-84-5Molecular Formula:C₂₂H₂₇N₂O₅PMolecular Weight:430.43Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:LY 311727 is an inhibitor of secretory phospholipase A2 (sPLA2) and can be used to block Pseudomonas aeruginosa cytotoxicity. It can also attenuate VEGF-mediated platelet-activating factor (PAF) synthesis in HUVEC and BAEC cells.References:Phillips, R., et al.: J. Biol. […]

4,4′-Methyl-methylene Trazodone Dimer-d12

Chemical Name:4,4′-Methyl-methylene Trazodone Dimer-d12Molecular Formula:C₄₀H₃₄D₁₂Cl₂N₁₀O₂Molecular Weight:781.84Category:Standards; Isotopic Labeled Analogues;Applications:4,4′-Methyl-methylene Trazodone Dimer-d12 is an isotopic analog of the impurity 4,4′-Methyl-methylene Trazodone Dimer (M260210).To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them […]

LY2562175

Chemical Name:LY2562175Synonyms:6-[4-[[5-Cyclopropyl-3-(2,6-dichlorophenyl)-4-isoxazolyl]methoxy]-1-piperidinyl]-1-methyl-1H-indole-3-carboxylic Acid; LY-2562175CAS Number:1103500-20-4Molecular Formula:C₂₈H₂₇Cl₂N₃O₄Molecular Weight:540.44Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:LY2562175, is a potent and selective FXR agonist with an EC50 of 193 nM.References:Genin, M. J. et al.: J. Med. Chem., 58, 9768 (2015).To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be […]

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