Chemical Name:AZ 10417808Synonyms:2-[(3,4-Dichlorophenyl)amino]-1,4-dihydro-6-nitro-4-oxo-N-2-propenyl-8-quinazolinecarboxamide; 2-[(3,4-Dichlorophenyl)amino]-1,4-dihydro-6-nitro-4-oxo-N-2-propenyl-8-quinazolinecarboxamide (9CI)CAS Number:331645-84-2Molecular Formula:C₁₈H₁₃Cl₂N₅O₄Molecular Weight:434.23Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:AZ 10417808 inhibits human caspase-3 with Ki values in the 90 to 800 nM range. AZ 10417808 blocks cellular and biochemical features of apoptosis in cells.References:Scott, C.W.; et al.: J. Pharmacol. Exp. Ther., 304, 433 (2003)To ensure the stability of our […]

Chemical Name:(2S,3S)-3-[[[(1S)-1-[[(4-Azidobutyl)amino]carbonyl]-3-methylbutyl]amino]carbonyl]-2-oxiranecarboxylic Acid Ethyl Ester-d8Synonyms:N3Le-d8Molecular Formula:C₁₆H₁₉D₈N₅O₅Molecular Weight:377.47Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Labelled N3Le is a derivative of E-64 an inhibitor of cathepsins B and L as well as a potential inhibitor of calpain. E-64d has been shown to inhibit lysosomal proteases.References:Song, J. et al.: Bioorg. Med. Chem. Lett., 23, 2801 (2013); Song, J. […]

Chemical Name:[2S-(2α,3β,5α)]-3-(Azidomethyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Phenylmethyl Ester 4,4-Dioxide-d4Alternate CAS #:117030-09-8Molecular Formula:C₁₅H₁₂D₄N₄O₅SMolecular Weight:368.4Category:Building Blocks; Chiral Molecules; Isotopic Labeled Analogues; Miscellaneous;Applications:[2S-(2α,3β,5α)]-3-(Azidomethyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Phenylmethyl Ester 4,4-Dioxide-d4 is an intermediate used in the synthesis of Tazobactam-d4 (T010097), which is the labeled analog of Tazobactam (T010095), a β-Lactamase inhibitor, used with β-lactam antibiotics to enhance their effect.References:Gould, I.M., et al.: Drugs Exp. […]

Chemical Name:5-[[[(2R)-2-Amino-3-[4-(aminocarbonyl)-2,6-dimethylphenyl]-1-oxopropyl][(1R)-1-(5-phenyl-1H-imidazol-2-yl)ethyl]amino]methyl]-2-methoxybenzoic acid (ACI)CAS Number:1052250-94-8Molecular Formula:C32H35N5O5Molecular Weight:569.65To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be wrapped with dried ice, and the […]

Chemical Name:(2R,3R,4R,5R,6R)-3-Acetamido-5-hydroxy-6-methyl-2-(2-(trimethylsilyl)ethoxy)tetrahydro-2H-pyran-4-yl AcetateMolecular Formula:C₁₅H₂₉NO₆SiMolecular Weight:347.48Category:Building Blocks; Carbohydrates; Miscellaneous;Applications:(2R,3R,4R,5R,6R)-3-Acetamido-5-hydroxy-6-methyl-2-(2-(trimethylsilyl)ethoxy)tetrahydro-2H-pyran-4-yl Acetate is an intermediate in the synthesis of N-((2S,3R,4R,6R)-2,4-Dihydroxy-6-methyl-5-oxotetrahydro-2H-pyran-3-yl)acetamide (D468230).To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely […]

Chemical Name:5,5′-((6-(((S)-1-(((S)-6-Amino-1-carboxyhexyl)amino)-6-(4-carboxybutanamido)-1-oxohexan-2-yl)amino)-6-oxohexane-1,5-diyl)bis(azanediyl))bis(5-oxopentanoic acid)Molecular Formula:C₃₄H₅₈N₆O₁₃Molecular Weight:758.87Category:Building Blocks; Miscellaneous;Applications:5,5′-((6-(((S)-1-(((S)-6-Amino-1-carboxyhexyl)amino)-6-(4-carboxybutanamido)-1-oxohexan-2-yl)amino)-6-oxohexane-1,5-diyl)bis(azanediyl))bis(5-oxopentanoic acid) is a useful organic compound.To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be […]

Chemical Name:Arjunolic AcidSynonyms:2α,3β,23-Trihydroxyolean-12-en-28-oic Acid;(2α,3β,4α)-2,3,23-Trihydroxyolean-12-en-28-oic Acid;2α,3β,23-Trihydroxyolean-12-en-28-oic Acid; Urjinolic AcidCAS Number:465-00-9Molecular Formula:C₃₀H₄₈O₅Molecular Weight:488.7Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Steroids;Applications:Arjunolic Acid is a naturally occurring terpenoid which displays anti-inflammatory activity as well as protective effects during chemical induced organ pathophysiology.References:Elsherbiny, N. et al.: Cytokine+, 77, 26 (2016);To ensure the stability of our products, the efficient express delivery service will be […]

Chemical Name:Abeprazan hydrochlorideCAS Number:1902954-87-3Molecular Formula:C19H17F3N2O3S.HClMolecular Weight:446.87To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be wrapped with dried ice, and the low […]

Chemical Name:2,3-Anhydro Rosuvastatin Methyl EsterSynonyms:(S,2E,6E)-Methyl 7-(4-(4-Fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-5-hydroxyhepta-2,6-dienoate; Rosuvastatin ImpurityMolecular Formula:C₂₃H₂₈FN₃O₅SMolecular Weight:477.55Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:2,3-Anhydro Rosuvastatin Methyl Ester is an impurity of Rosuvastatin (R700500, Ca Salt); a selective, competitive HMG-CoA reductase inhibitor and antilipemic agent.References:Watanabe, M., et al.: Bioorg. Med. Chem., 5, 437 (1997); Lee, E., et al.: Clin. Pharmacol. Ther., 78, 330 (2005); Ferdinand, K.C., et […]

Chemical Name:4’’-Descyano,4’’carboxaamido-enzalutmaide-D3Synonyms:Enzalutmaide Impurity 6-D3Alternate CAS #:2030242-21-6Molecular Formula:C₂₁H₁₅D₃F₄N₄O₃SMolecular Weight:485.47Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;Applications:The deuterated isotope of 4’’-Descyano,4’’carboxaamido-enzalutmaide which is useful in cancer treatment.References:Tomasz, M.B., et al.: New Engl, J. Med., 424, 371 (2014);To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will […]