Chemical Name:(3S,8S,9S,12R)-AtazanavirSynonyms:(3S,8S,9S,12R)-3,12-Bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-2,5,6,10,13-pentaazatetradecanedioic Acid 1,14-Dimethyl EsterCAS Number:1332981-16-4Molecular Formula:C₃₈H₅₂N₆O₇Molecular Weight:704.86Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:(3S,8S,9S,12R)-Atazanavir is an impurity of Atazanavir (A790051); a novel azapeptide HIV protease inhibitor (PI) and antiviral agent.References:Palella, F.J. Jr., et al.: N. Engl. J. Med., 338(13), 853 (1998); Nolan, D., et al.: Drugs, 63(23), 2555 (2003); Musial, B.L., et al.: Am. […]

Chemical Name:3-Hydroxy-N-methoxy BavarostatSynonyms:4-((((3r,5r,7r)-adamantan-1-ylmethyl)(methyl)amino)methyl)-3-hydroxy-N-methoxybenzamidMolecular Formula:C₂₁H₃₀N₂O₃Molecular Weight:358.47Category:Research Tools; Molecular Biology; Enzyme Activators and Inhibitors;Applications:3-Hydroxy-N-methoxy Bavarostat is the radiofluorination precursor for the synthesis of [18F]Bavarostat which acts as a HDAC6 (Histone deacetylase 6) inhibitor in cancer cells and central nervous system.References:Strebl, M. G., et al.: ACS Cent. Sci., 3, 1006-1014 (2017)To ensure the stability of our products, the […]

Chemical Name:3-[[[[[(5S)-5-Amino-5-carboxypentyl]amino]carbonyl]oxy]methyl]-2,5-dihydro-2,2,5,5-tetramethyl-1H-pyrrol-1-yloxySynonyms:Spin-labeled Lysine; SLK-1CAS Number:1536470-17-3Molecular Formula:C₁₆H₂₈N₃O₅Molecular Weight:342.41Category:Research Tools; Standards; Molecular Biology; Spin Labels;Applications:3-[[[[[(5S)-5-Amino-5-carboxypentyl]amino]carbonyl]oxy]methyl]-2,5-dihydro-2,2,5,5-tetramethyl-1H-pyrrol-1-yloxy is a spin-labeledl lysine, used to measure electron paramagnetic resonance distance.References:Schmidt, M., et al.: J. Am. Chem. Soc., 136, 1238 (2014); Schmidt, M., et al.: ACS Chem. Biol., 10, 2764 (2015);To ensure the stability of our products, the efficient express delivery service […]

Chemical Name:5-​[[[[[(5S)​-​5-​Amino-​5-​carboxypentyl]​amino]​carbonyl]​oxy]​methyl]​-​1,​3-​dihydro-​1,​1,​3,​3-​tetramethyl-2H-​isoindol-​2-​yloxyCAS Number:1801598-39-9Molecular Formula:C₂₀H₃₀N₃O₅Molecular Weight:392.47Category:Research Tools;Applications:5-​[[[[[(5S)​-​5-​Amino-​5-​carboxypentyl]​amino]​carbonyl]​oxy]​methyl]​-​1,​3-​dihydro-​1,​1,​3,​3-​tetramethyl-2H-​isoindol-​2-​yloxy, a spin-labeled reagent, was used as tyrosine aminoxy radical derivative to generate proteins having genetically encoded spin labels.References:Summerer, D., et al.: PCT Int. Appl. (2015), WO 2015107071 A1 20150723.To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products […]

Chemical Name:ATL-313-d4Synonyms:4-[3-[6-Amino-9-(N-cyclopropyl-β-D-ribofuranuronamidosyl)-9H-purin-2-yl]-2-propyn-1-yl]-1-piperidinecarboxylic Acid-d4 Methyl Ester; DE 112-d4; Evodenoson-d4Molecular Formula:C₂₃H₂₅D₄N₇O₆Molecular Weight:503.54Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Isotope labelled analogue of ATL-313, an adenosine A2A receptor agonists used as a potential treatment for spinal cord injury in preventing the apoptotic process that is an important step of secondary damage after spinal cord injury.References:Genovese, T., et al.: J. […]

Chemical Name:AtroviridinSynonyms:5,8,12-Trihydroxy-2,2-dimethyl-2H,6H-Pyrano[3,2-b]xanthen-6-oneCAS Number:207984-34-7Molecular Formula:C₁₈H₁₄O₆Molecular Weight:326.3Category:Building Blocks;Applications:Atroviridin is a xanthone natural product which displays antiproliferaitive activity.References:Tisdale, E. et al.: Tetrahedron Lett., 44, 3281 (2003); Suzuki, Y. et al.: J. Org. Chem., 76, 3960 (2011);To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be […]

Chemical Name:2,3-Anhydro Rosuvastatin Methyl EsterSynonyms:(S,2E,6E)-Methyl 7-(4-(4-Fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-5-hydroxyhepta-2,6-dienoate; Rosuvastatin ImpurityMolecular Formula:C₂₃H₂₈FN₃O₅SMolecular Weight:477.55Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:2,3-Anhydro Rosuvastatin Methyl Ester is an impurity of Rosuvastatin (R700500, Ca Salt); a selective, competitive HMG-CoA reductase inhibitor and antilipemic agent.References:Watanabe, M., et al.: Bioorg. Med. Chem., 5, 437 (1997); Lee, E., et al.: Clin. Pharmacol. Ther., 78, 330 (2005); Ferdinand, K.C., et […]

Chemical Name:4’’-Descyano,4’’carboxaamido-enzalutmaide-D3Synonyms:Enzalutmaide Impurity 6-D3Alternate CAS #:2030242-21-6Molecular Formula:C₂₁H₁₅D₃F₄N₄O₃SMolecular Weight:485.47Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;Applications:The deuterated isotope of 4’’-Descyano,4’’carboxaamido-enzalutmaide which is useful in cancer treatment.References:Tomasz, M.B., et al.: New Engl, J. Med., 424, 371 (2014);To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will […]

Chemical Name:1-(Acetyloxy)-2-hydroxy-4-heptadecanoneSynonyms:2-Hydroxy-4-oxoheptadecyl AcetateCAS Number:25346-19-4Molecular Formula:C₁₉H₃₆O₄Molecular Weight:328.49Category:Standards; Food; Lipids/Fatty Acids, Glycerol Derivatives;Applications:1-(Acetyloxy)-2-hydroxy-4-heptadecanone is a polyhydroxylated fatty alcohol from avocado pear.To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The […]

Chemical Name:AR-42Synonyms:(αS)-N-[4-[(Hydroxyamino)carbonyl]phenyl]-α-(1-methylethyl)benzeneacetamide; (S)-(+)-N-Hydroxy-4-(3-methyl-2-phenyl-butyrylamino)-benzamide; (S)-HDAC 42; OSU-HDAC 42CAS Number:935881-37-1Molecular Formula:C₁₈H₂₀N₂O₃Molecular Weight:312.36Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:AR-42 is a broad spectrum deacetylase inhibitor of both histone and non-histone proteins, which has demonstrated greater potency and activity in solid tumors and hematological malignancies. AR-42 is known utilized as a novel, oral cancer therapy currently in early clinical development.References:Bai, L.Y., et […]