Chemical Name:1,8-Bis(4-((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzyl)-1,4,8,11-tetraazacyclotetradecaneSynonyms:Plexifor Impurity II;CAS Number:414858-02-9Molecular Formula:C₄₆H₈₄N₁₂Molecular Weight:805.24Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:1,8-Bis(4-((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzyl)-1,4,8,11-tetraazacyclotetradecane is an impurity of Plerixafor (P580500), a hematopoietic stem cell (HSC) mobilizer that inhibits the CXCR4 chemokine receptor and blocks binding of its ligand, stromal cell-derived factor-1-α (SDF-1-α). This agent was approved on Dec. 15, 2008, as treatment in combination with […]

Chemical Name:BIX-01338 HydrateSynonyms:1-​[2-​[4-​[(4-​Methoxybenzoyl)​oxy]​phenyl]​ethyl]​-​2-​[[4-​(trifluoromethyl)​benzoyl]​amino]​-​1H-​Benzimidazole-​5-​carboxylic Acid HydrateCAS Number:1228184-65-3Molecular Formula:C₃₂H₂₄F₃N₃O₆ • H ₂OMolecular Weight:603.54 + (18.02)Category:Standards; Enzyme Activators and Inhibitors;Applications:BIX-01338 Hydrate is the hydrate form of BIX-01338, which is a non-selective histone lysine methyltransferase inhibitor.References:Yuan Y., et al.: J. Amer. Chem. Soc., 7, 1152 (2012)To ensure the stability of our products, the efficient express delivery service will be […]

Chemical Name:BMS 188745 Potassium SaltSynonyms:(αS)-3-Phenoxy-α-phosphonobenzenebutanesulfonic Acid Tripotassium Salt;CAS Number:157126-15-3Alternate CAS #:188526-11-6Molecular Formula:C₁₆H₁₆K₃O₇PSMolecular Weight:500.63Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Potassium salts of aralkylphosphonosulfonic acids are prepared as inhibitors of dehydrosqualene synthase (CrtM) in order to inhibit the biosynthesis of the Staphylococcus aureus virulence factor staphyloxanthin.References:Magnin, D., et al.: J. Med. Chem., 39, 657 (1996), Sharma, […]

Chemical Name:BMS-265246Synonyms:(4-Butoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)(2,6-difluoro-4-methylphenyl)methanone;CAS Number:582315-72-8Molecular Formula:C₁₈H₁₇F₂N₃O₂Molecular Weight:345.34Category:Research Tools;Applications:BMS-265246 is a potent and selective pyra-zolopyridine based inhibitor of cdk2/cyclinE, cdk1/cyclinB and cdk4/ cyclinD.References:Raj, N.M., et al.: Bioorg. Medn. Chem. Letters., 13, 2405 (2003);To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the […]

Chemical Name:2’,3-(Boc-amino) 3’’-(Boc-methylamino) N-Boc Des(2-hydroxyethyl) PlazomicinSynonyms:O-6-Amino-2,3,4,6-tetradeoxy-2-[[(1,1-dimethylethoxy)carbonyl]amino]-α-D-glycero-hex-4-enopyranosyl-(1→4)-O-[3-deoxy-3-[[(1,1-dimethylethoxy)carbonyl]methylamino]-4-C-methyl-β-L-arabinopyranosyl-(1→6)]-2-deoxy-N3-[(1,1-dimethylethoxy)carbonyl]-N1-[(2S)-4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-hydroxy-1-oxobutyl]-D-streptamineCAS Number:1154758-63-0Molecular Formula:C₄₃H₇₆N₆O₁₇Molecular Weight:949.09Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics;Applications:2’,3-(Boc-amino) 3’’-(Boc-methylamino) N-Boc Des(2-hydroxyethyl) Plazomicin is an intermediate in the synthesis of Plazomicin Sulfate (P579505), the acidic salt of Plazomicin (P579500). Plazomicin is a neoglycoside antibiotic with activity against a broad range of Gram-positive and Gram-negive pathogens. Plazomicin showed potent in vitro activity […]

Chemical Name:5-​[7-​(1-​Bromoethyl)​-​2-​benzofuranyl]​-​3-​(1,​1-​dimethylethyl)​-2-​oxazolidinoneSynonyms:5-(7-(1-Bromoethyl)benzofuran-2-yl)-3-(tert-butyl)oxazolidin-2-oneCAS Number:2125944-56-9Molecular Formula:C₁₇H₂₀BrNO₃Molecular Weight:366.25Category:Building Blocks; Miscellaneous; Pharmaceutical/API Drug Impurities/Metabolites;Applications:5-​[7-​(1-​Bromoethyl)​-​2-​benzofuranyl]​-​3-​(1,​1-​dimethylethyl)​-2-​oxazolidinone is an intermediate in the synthesis of 1’-Hydroxy Bufuralol (Mixture of Diastereomers) (H830480) which is a metabolite of Bufuralol, a β-Adrenergic blocker with peripheral vasodilating activity.References:Boobis, A.R., et al.: Biochem. Pharmacol., 34, 65 (1985), Yamazaki, H., et al.: Mol. Pharmacol., 46, 568 (1994), Mast, N., […]

Chemical Name:BAR 502-d5Synonyms:(3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-17-((R)-4-Hydroxybutan-2-yl)-10,13-dimethyl-6-(methyl-d)hexadecahydro-1H-cyclopenta[a]phenanthrene-2,2,3,4,4-d5-3,7-diolAlternate CAS #:1612191-86-2Molecular Formula:C₂₄H₃₆D₆O₃Molecular Weight:384.64Category:Building Blocks; Isotopic Labeled Analogues; Miscellaneous; Pharmaceutical/API Drug Impurities/Metabolites;Applications:BAR 502-d5 is a labelled analogue of BAR 502 (B161220), which can be used to treat hepatitis D virus infection.References:Darteil, R., et.al.: PCT Int. Appl. WO 2021144330 A1, 38, (2021);To ensure the stability of our products, the efficient express delivery service […]

Chemical Name:(R)-N-(3-(2-(Benzyloxy)-5-formylphenyl)-3-phenylpropyl)-N-isopropylnitrous amideMolecular Formula:C26H28N2O3Molecular Weight:416.5Category:Building Blocks; Miscellaneous;Applications:(R)-N-(3-(2-(Benzyloxy)-5-formylphenyl)-3-phenylpropyl)-N-isopropylnitrous amide is a useful research chemicalTo ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be […]

Chemical Name:(2S)-5-(((6R,7S)-4-(6-(Benzyloxy)-6-oxohexyl)-6,7,8a-trihydroxy-4,5,6,7,8,8a-hexahydroimidazo[4,5-b]azepin-2-yl)amino)-2-(((benzyloxy)carbonyl)amino)pentanoic AcidMolecular Formula:C₃₃H₄₃N₅O₉Molecular Weight:653.72Category:Building Blocks; Miscellaneous;Applications:(2S)-5-(((6R,7S)-4-(6-(Benzyloxy)-6-oxohexyl)-6,7,8a-trihydroxy-4,5,6,7,8,8a-hexahydroimidazo[4,5-b]azepin-2-yl)amino)-2-(((benzyloxy)carbonyl)amino)pentanoic Acid is an intermediate in synthesizing (6R,7R,8a-rac)-(5”-Desamino Glucosepane (D288468), a derivative of Glucosepane, which is a structurally complex protein posttranslational modification that is believed a exist in all living organisms. Research in humans suggests that glucosepane plays a critical role in the pathophysiology of both diabetes and human […]

Chemical Name:Benzo[a]​pyrene-​9,​10-​diol-d10Synonyms:9,10-Dihydroxybenzo[a]pyrene-d10Alternate CAS #:57303-98-7 unlabelledMolecular Formula:C₂₀H₂D₁₀O₂Molecular Weight:294.37Category:Standards; Isotopic Labeled Analogues; Environmental Standards, Mutagens and Metabolites;Applications:Benzo[a]​pyrene-​9,​10-​diol-d10 is labelled Benzo[a]​pyrene-​9,​10-​diol (B205825) which is a metabolite of Benzopyrene (B205800). Benzopyrene is a known carcinogen.References:Strickland, P., et al.: Carcinogenesis, 15, 483 (1994); Ramesh, A., et al.: Exp. Toxicol. Pathol., 53, 275 (2001)To ensure the stability of our products, the […]