Chemical Name:1,8-Bis(4-((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzyl)-1,4,8,11-tetraazacyclotetradecaneSynonyms:Plexifor Impurity II;CAS Number:414858-02-9Molecular Formula:C₄₆H₈₄N₁₂Molecular Weight:805.24Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:1,8-Bis(4-((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzyl)-1,4,8,11-tetraazacyclotetradecane is an impurity of Plerixafor (P580500), a hematopoietic stem cell (HSC) mobilizer that inhibits the CXCR4 chemokine receptor and blocks binding of its ligand, stromal cell-derived factor-1-α (SDF-1-α). This agent was approved on Dec. 15, 2008, as treatment in combination with […]

Chemical Name:BIX-01338 HydrateSynonyms:1-​[2-​[4-​[(4-​Methoxybenzoyl)​oxy]​phenyl]​ethyl]​-​2-​[[4-​(trifluoromethyl)​benzoyl]​amino]​-​1H-​Benzimidazole-​5-​carboxylic Acid HydrateCAS Number:1228184-65-3Molecular Formula:C₃₂H₂₄F₃N₃O₆ • H ₂OMolecular Weight:603.54 + (18.02)Category:Standards; Enzyme Activators and Inhibitors;Applications:BIX-01338 Hydrate is the hydrate form of BIX-01338, which is a non-selective histone lysine methyltransferase inhibitor.References:Yuan Y., et al.: J. Amer. Chem. Soc., 7, 1152 (2012)To ensure the stability of our products, the efficient express delivery service will be […]

Chemical Name:BMS 188745 Potassium SaltSynonyms:(αS)-3-Phenoxy-α-phosphonobenzenebutanesulfonic Acid Tripotassium Salt;CAS Number:157126-15-3Alternate CAS #:188526-11-6Molecular Formula:C₁₆H₁₆K₃O₇PSMolecular Weight:500.63Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Potassium salts of aralkylphosphonosulfonic acids are prepared as inhibitors of dehydrosqualene synthase (CrtM) in order to inhibit the biosynthesis of the Staphylococcus aureus virulence factor staphyloxanthin.References:Magnin, D., et al.: J. Med. Chem., 39, 657 (1996), Sharma, […]

Chemical Name:BMS-265246Synonyms:(4-Butoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)(2,6-difluoro-4-methylphenyl)methanone;CAS Number:582315-72-8Molecular Formula:C₁₈H₁₇F₂N₃O₂Molecular Weight:345.34Category:Research Tools;Applications:BMS-265246 is a potent and selective pyra-zolopyridine based inhibitor of cdk2/cyclinE, cdk1/cyclinB and cdk4/ cyclinD.References:Raj, N.M., et al.: Bioorg. Medn. Chem. Letters., 13, 2405 (2003);To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the […]

Chemical Name:2’,3-(Boc-amino) 3’’-(Boc-methylamino) N-Boc Des(2-hydroxyethyl) PlazomicinSynonyms:O-6-Amino-2,3,4,6-tetradeoxy-2-[[(1,1-dimethylethoxy)carbonyl]amino]-α-D-glycero-hex-4-enopyranosyl-(1→4)-O-[3-deoxy-3-[[(1,1-dimethylethoxy)carbonyl]methylamino]-4-C-methyl-β-L-arabinopyranosyl-(1→6)]-2-deoxy-N3-[(1,1-dimethylethoxy)carbonyl]-N1-[(2S)-4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-hydroxy-1-oxobutyl]-D-streptamineCAS Number:1154758-63-0Molecular Formula:C₄₃H₇₆N₆O₁₇Molecular Weight:949.09Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics;Applications:2’,3-(Boc-amino) 3’’-(Boc-methylamino) N-Boc Des(2-hydroxyethyl) Plazomicin is an intermediate in the synthesis of Plazomicin Sulfate (P579505), the acidic salt of Plazomicin (P579500). Plazomicin is a neoglycoside antibiotic with activity against a broad range of Gram-positive and Gram-negive pathogens. Plazomicin showed potent in vitro activity […]

Chemical Name:5-​[7-​(1-​Bromoethyl)​-​2-​benzofuranyl]​-​3-​(1,​1-​dimethylethyl)​-2-​oxazolidinoneSynonyms:5-(7-(1-Bromoethyl)benzofuran-2-yl)-3-(tert-butyl)oxazolidin-2-oneCAS Number:2125944-56-9Molecular Formula:C₁₇H₂₀BrNO₃Molecular Weight:366.25Category:Building Blocks; Miscellaneous; Pharmaceutical/API Drug Impurities/Metabolites;Applications:5-​[7-​(1-​Bromoethyl)​-​2-​benzofuranyl]​-​3-​(1,​1-​dimethylethyl)​-2-​oxazolidinone is an intermediate in the synthesis of 1’-Hydroxy Bufuralol (Mixture of Diastereomers) (H830480) which is a metabolite of Bufuralol, a β-Adrenergic blocker with peripheral vasodilating activity.References:Boobis, A.R., et al.: Biochem. Pharmacol., 34, 65 (1985), Yamazaki, H., et al.: Mol. Pharmacol., 46, 568 (1994), Mast, N., […]

Chemical Name:7-(But-2-yn-1-yl)-3-methyl-8-((3R)-3-(1-methyl-2-(piperidin-3-yl-4,4,5,5,6,6-D₆)hydrazineyl)piperidin-1-yl)-1-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione HydrochlorideMolecular Formula:C₃₁H₃₄D₆N₁₀O₂ • HClMolecular Weight:627.22Category:Building Blocks; Miscellaneous;To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be wrapped with dried ice, […]

Chemical Name:(S)-2-(((Benzyloxy)carbonyl)amino)-3-methylbutanoyl O-Benzyl Ganciclovir DimerSynonyms:(2S)-2-((6-(Benzyloxy)-2-((((6-(benzyloxy)-9-(((1,3-dihydroxypropan-2-yl)oxy)methyl)-9H-purin-2-yl)amino)methyl)amino)-9H-purin-9-yl)methoxy)-3-hydroxypropyl 2-(((benzyloxy)carbonyl)amino)-3-methylbutanoateMolecular Formula:C₄₆H₅₃N₁₁O₁₁Molecular Weight:935.98Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:(S)-2-(((Benzyloxy)carbonyl)amino)-3-methylbutanoyl O-Benzyl Ganciclovir Dimer is an intermediate in the synthesis of Valganciclovir N3,N3′-Methylene Dimer (V092015) which is an impurity of Valganciclovir (V092000), a pro-drug of Ganciclovir (G235000) . Used in treatment of retro-virus.References:Acosta, E., et al.: Clin. Pharmacol. Ther., 81, 867 (2007), Nassetta, L., et […]

Chemical Name:(S)-4-Boc-2-methylpiperazine-5,5-D2Synonyms:(S)-1-Boc-3-methylpiperazine-D2; (S)-1-tert-Butoxycarbonyl-3-methylpiperazine-D2;(S)-3-Methylpiperazine-1-carboxylic Acid tert-Butyl Ester-D2; (S)-4-(tert-Butoxycarbonyl)-2-methylpiperazine-D2;(S)-4-Boc-2-methylpiperazine-D2; (S)-tert-Butyl 3-methylpiperazine-1-carboxylate-D2;1,1-Dimethylethyl (3S)-3-Methyl-1-piperazinecarboxylate-D2;1,1-Dimethylethyl (S)-3-Methyl-1-piperazinecarboxylate-D2; 3-(S)-Methyl-1-(tert-butoxycarbonyl)piperazine-D2; 3-Methylpiperazine-1-carboxylic Acid (S)-tert-Butyl Ester-D2; N-tert-Butoxycarbonyl-2(S)-methylpiperazine-D2; tert-Butyl (3S)-3-Methylpiperazine-1-carboxylate-D2; tert-Butyl (S)-3-Methylpiperazine-1-carboxylate-D2;Molecular Formula:C₁₀H₁₈D₂N₂O₂Molecular Weight:202.29Category:Building Blocks; Isotopic Labeled Analogues;Applications:(S)-4-Boc-2-methylpiperazine-5,5-D2 is a deuterium labelled analogue of (S)-4-Boc-2-methylpiperazine (B656830), which is used as reagent in the synthesis of benzamide peptidomimetic as non-ATP competitive inihbitors.References:Premnath, P. et al.: Bioorg. Med. […]

Chemical Name:(2-((3R,5R)-3,5-Bis((tert-butyldimethylsilyl)oxy)-4-methylenecyclohexylidene)ethyl)diphenylphosphine OxideSynonyms:[2-[(3R,5R)-3,5-Bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-methylenecyclohexylidene]ethyl]diphenylphosphine Oxide; [2-[(3R,5R)-3,5-Bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-methylenecyclohexylidene]ethyl]diphenylphosphine Oxide;CAS Number:213250-64-7Molecular Formula:C₃₃H₅₁O₃PSi₂Molecular Weight:582.9Category:Building Blocks; Miscellaneous;Applications:(2-((3R,5R)-3,5-Bis((tert-butyldimethylsilyl)oxy)-4-methylenecyclohexylidene)ethyl)diphenylphosphine Oxide is an intermediate used in the preparation of vitamin D3 analogsReferences:Chiellini, G., et al.: Steroids, 83, 27 (2014); Chen, B., et al.: Bioorg. Med. Chem. Lett., 23, 5949 (2013)To ensure the stability of our products, the efficient express delivery service will be used. […]