Chemical Name:Brilacidin TetrahydrochlorideSynonyms:PMX 30063 Tetrahydrochloride; N4,N6-Bis[3-[[5-[(aminoiminomethyl)amino]-1-oxopentyl]amino]-2-[(3R)-3-pyrrolidinyloxy]-5-(trifluoromethyl)phenyl]-4,6-pyrimidinedicarboxamide HydrochlorideCAS Number:1224095-99-1Molecular Formula:C₄₀H₅₄Cl₄F₆N₁₄O₆Molecular Weight:1082.75Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Brilacidin Tetrahydrochloride is a defensin mimetic.References:Scott, R.W.: Am. Biotech. Lab., 27, 16 (2009)To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes […]

Chemical Name:(S)-tert-Butyl 1-((2S,3S)-3-Amino-4-(tert-butoxy)-2-((tert-butyldimethylsilyl)oxy)-4-oxobutyl)azetidine-2-carboxylateMolecular Formula:C₂₂H₄₄N₂O₅SiMolecular Weight:444.68Category:Building Blocks; Chiral Molecules; Amino Acids; Miscellaneous;Applications:(S)-tert-Butyl 1-((2S,3S)-3-Amino-4-(tert-butoxy)-2-((tert-butyldimethylsilyl)oxy)-4-oxobutyl)azetidine-2-carboxylate is an intermediate for the synthesis of Mugineic Acid Ammonium Salt (M792005). Mugineic Acid, a possible phytosiderophore of graminaceous plants, has iron chelation potency and antioxidant activity.References:Takagi, S., et al.: J. Plant. Nutr., 7, 469 (1984); Das, P., et al.: Nat. Prod. Res., […]

Chemical Name:Brinzolamide Methanesulfonyl AmideAlternate CAS #:138890-62-7Molecular Formula:C₁₃H₂₃N₃O₇S₄Molecular Weight:461.6Category:Research Tools; Molecular Biology; Enzyme Activators and Inhibitors;Applications:Brinzolamide Methanesulfonyl Amide is an impurity of Brinzolamide (B677600, HCl salt) which is a carbonic anhydrase inhibitor.References:Silver, L.H., et al.: Am. J. Ophthalmol., 126, 400 (1998); Davies, N., et al.: Clin. Exp. Pharmacol. Physiol., 27, 558 (2000); Stave, J., et al.: […]

Chemical Name:(S)-BrinzolamideSynonyms:(S)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-Dioxide, ; AL 4862; Brinzolamide USP Related Compound AImpurityBrinzolamide USP Related Compound ACAS Number:154127-19-2Molecular Formula:C₁₂H₂₁N₃O₅S₃Molecular Weight:383.51Category:Research Tools;Applications:(S)-Brinzolamide is an isomer of Brinzolamide (B677601), Carbonic anhydrase inhibitor. Antiglaucoma agent.References:Silver, L.H., et al.: Am. J. Ophthalmol., 126, 400 (1998), Davies, N., et al.: Clin. Exp. Pharmacol. Physiol., 27, 558 (2000), Stave, J., et al.: Ophthalmologe, […]

Chemical Name:(S)-Brinzolamide (Ethyl-d5)Synonyms:(S)-4-(Ethyl-d5-amino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-Dioxide; AL 4862-d5;Molecular Formula:C₁₂H₁₆D₅N₃O₅S₃Molecular Weight:388.54Category:Building Blocks; Isotopic Labeled Analogues;Applications:(S)-Brinzolamide-d5 is the labeled analogue of (S)-Brinzolamide (B677605), an isomer of Brinzolamide (B677601), a carbonic anhydrase inhibitor. Antiglaucoma agent.References:Silver, L.H., et al.: Am. J. Ophthalmol., 126, 400 (1998); Davies, N., et al.: Clin. Exp. Pharmacol. Physiol., 27, 558 (2000); Stave, J., et al.: Ophthalmologe, […]

Chemical Name:αR,4S-Brivaracetam-d7Synonyms:(αR,4S)-α-Ethyl-2-oxo-4-propyl-1-pyrrolidineacetamide-d7Molecular Formula:C₁₁H₁₃D₇N₂O₂Molecular Weight:219.33Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;Applications:αR,4S-Brivaracetam-d7 is an isotope labelled compound of (B677690). αR,4S-Brivaracetam acts as a reagent for the preparation of 2-Oxo-1-pyrrolidine derivatives and their anticonvulsants activity. Also an impurity of Brivaracetam (B677645), a 4-n-propyl analog of levetiracetam (L331500), and a racetam derivative with anticonvulsant properties.References:Differding, E., et al.: PCT […]

Chemical Name:(S)-N-((S)-1-Amino-1-oxobutan-2-yl)-2-((R)-2-oxo-4-propylpyrrolidin-1-yl)butanamideSynonyms:Brivaracetam-N-butyramideCAS Number:2432911-32-3Molecular Formula:C₁₅H₂₇N₃O₃Molecular Weight:297.39Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Brivaracetam-N-butyramide is an impurity of Brivaracetam (B677645). Brivaracetam, is a 4-n-propyl analog of levetiracetam (L331500), and a racetam derivative with anticonvulsant properties.References:Rosenstiel, P., et al.:Neurotherapeutics, 4 (1), 84 (2007); Malawska, B., et al.:, Curr. Opin. Investig. Drugs, 6(7), 740 (2005);To ensure the stability of our products, the efficient […]

Chemical Name:BMS-265246Synonyms:(4-Butoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)(2,6-difluoro-4-methylphenyl)methanone;CAS Number:582315-72-8Molecular Formula:C₁₈H₁₇F₂N₃O₂Molecular Weight:345.34Category:Research Tools;Applications:BMS-265246 is a potent and selective pyra-zolopyridine based inhibitor of cdk2/cyclinE, cdk1/cyclinB and cdk4/ cyclinD.References:Raj, N.M., et al.: Bioorg. Medn. Chem. Letters., 13, 2405 (2003);To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the […]

Chemical Name:2’,3-(Boc-amino) 3’’-(Boc-methylamino) N-Boc Des(2-hydroxyethyl) PlazomicinSynonyms:O-6-Amino-2,3,4,6-tetradeoxy-2-[[(1,1-dimethylethoxy)carbonyl]amino]-α-D-glycero-hex-4-enopyranosyl-(1→4)-O-[3-deoxy-3-[[(1,1-dimethylethoxy)carbonyl]methylamino]-4-C-methyl-β-L-arabinopyranosyl-(1→6)]-2-deoxy-N3-[(1,1-dimethylethoxy)carbonyl]-N1-[(2S)-4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-hydroxy-1-oxobutyl]-D-streptamineCAS Number:1154758-63-0Molecular Formula:C₄₃H₇₆N₆O₁₇Molecular Weight:949.09Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics;Applications:2’,3-(Boc-amino) 3’’-(Boc-methylamino) N-Boc Des(2-hydroxyethyl) Plazomicin is an intermediate in the synthesis of Plazomicin Sulfate (P579505), the acidic salt of Plazomicin (P579500). Plazomicin is a neoglycoside antibiotic with activity against a broad range of Gram-positive and Gram-negive pathogens. Plazomicin showed potent in vitro activity […]

Chemical Name:5-​[7-​(1-​Bromoethyl)​-​2-​benzofuranyl]​-​3-​(1,​1-​dimethylethyl)​-2-​oxazolidinoneSynonyms:5-(7-(1-Bromoethyl)benzofuran-2-yl)-3-(tert-butyl)oxazolidin-2-oneCAS Number:2125944-56-9Molecular Formula:C₁₇H₂₀BrNO₃Molecular Weight:366.25Category:Building Blocks; Miscellaneous; Pharmaceutical/API Drug Impurities/Metabolites;Applications:5-​[7-​(1-​Bromoethyl)​-​2-​benzofuranyl]​-​3-​(1,​1-​dimethylethyl)​-2-​oxazolidinone is an intermediate in the synthesis of 1’-Hydroxy Bufuralol (Mixture of Diastereomers) (H830480) which is a metabolite of Bufuralol, a β-Adrenergic blocker with peripheral vasodilating activity.References:Boobis, A.R., et al.: Biochem. Pharmacol., 34, 65 (1985), Yamazaki, H., et al.: Mol. Pharmacol., 46, 568 (1994), Mast, N., […]