Chemical Name:(+)-Calanolide ASynonyms:(10R,11S,12S)-11,12-Dihydro-12-hydroxy-6,6,10,11-tetramethyl-4-propyl-2H,6H,10H-benzo[1,2-b:3,4-b’:5,6-b”]tripyran-2-one; [10R-(10α,11β,12α)]-11,12-Dihydro-12-hydroxy-6,6,10,11-tetramethyl-4-propyl-2H,6H,10H-benzo[1,2-b:3,4-b’:5,6-b”]tripyran-2-one; Calanolide A; NSC 650886CAS Number:142632-32-4Molecular Formula:C₂₂H₂₆O₅Molecular Weight:370.44Category:Research Tools;Applications:(+)-Calanolide A is an experimental non-nucleoside reverse transcriptase inhibitor. It has potent anti-HIV activity.References:Kashman, Y., et al.: J. Med. Chem., 35, 2735 (1992); Jorgensen, W., et al.: Bioorg. Med. Chem. Lett., 16, 663 (2006)To ensure the stability of our products, the efficient express delivery […]
((4-(7-(2-(4-Chlorophenoxy)ethyl)-2-(methylamino)-6-oxo-6,7-dihydro-3H-purin-8-yl)phenyl)difluoromethyl)phosphonic Acid
Chemical Name:((4-(7-(2-(4-Chlorophenoxy)ethyl)-2-(methylamino)-6-oxo-6,7-dihydro-3H-purin-8-yl)phenyl)difluoromethyl)phosphonic AcidCAS Number:1373822-46-8Molecular Formula:C₂₁H₁₉ClF₂N₅O₅PMolecular Weight:525.83Category:Building Blocks; Miscellaneous;Applications:((4-(7-(2-(4-Chlorophenoxy)ethyl)-2-(methylamino)-6-oxo-6,7-dihydro-3H-purin-8-yl)phenyl)difluoromethyl)phosphonic Acid is used as an intermediate in the synthesis of guanine-derived inhibitors of eIF4E mRNA-cap interaction.References:Chen, X., et al.: J. Med. Chem., 55, 3837 (2012)To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be […]
(1S,3R)-3-(5-(5-Chloro-2-ethoxyphenyl)-1,3,4-oxadiazol-2-yl)-N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)cyclohexanecarboxamide
Chemical Name:(1S,3R)-3-(5-(5-Chloro-2-ethoxyphenyl)-1,3,4-oxadiazol-2-yl)-N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)cyclohexanecarboxamideCAS Number:1807337-46-7Molecular Formula:C₂₈H₃₀ClN₅O₄Molecular Weight:536.02Category:Building Blocks; Miscellaneous;Applications:(1S,3R)-3-(5-(5-Chloro-2-ethoxyphenyl)-1,3,4-oxadiazol-2-yl)-N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)cyclohexanecarboxamide is a useful intermediate for organic synthesis.To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will […]
3-(6-Chloropyrimidin-4-yl)-5-(1-methylcyclopropoxy)-2-((2-(trimethylsilyl)ethoxy)methyl)-2H-indazole
Chemical Name:3-(6-Chloropyrimidin-4-yl)-5-(1-methylcyclopropoxy)-2-((2-(trimethylsilyl)ethoxy)methyl)-2H-indazoleCAS Number:1627093-41-7Molecular Formula:C₂₁H₂₇ClN₄O₂SiMolecular Weight:431Category:Building Blocks; Miscellaneous;Applications:3-(6-Chloropyrimidin-4-yl)-5-(1-methylcyclopropoxy)-2-((2-(trimethylsilyl)ethoxy)methyl)-2H-indazole is a useful intermediate in the development of MLi-2 (3-(4-Pyrimidinyl) Indazole), a potent orally available brain penetrant inhibitor of LRRK2.References:Scott, J. D., et al.: J. Med. Chem., 60, 2983 (2017);To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that […]
Candoxatril
Chemical Name:CandoxatrilSynonyms:cis-4-[[[1-[(2S)-3-[(2,3-Dihydro-1H-inden-5-yl)oxy]-2-[(2-methoxyethoxy)methyl]-3-oxopropyl]cyclopentyl]carbonyl]amino]cyclohexanecarboxylic Acid; UK 79300;CAS Number:123122-55-4Molecular Formula:C₂₉H₄₁NO₇Molecular Weight:515.64Category:Research Tools;Applications:Neutral endopeptidase inhibitor. Used in treatment of congestive heart failure.References:Motwani, J.G., et al.: Clin. Pharmacol. Ther., 54, 661 (1993), Kimmelstiel, C.D., et al.: Cardiology, 87, 46 (1996),To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products […]
Cangrelor
Chemical Name:CangrelorSynonyms:N-[2-(Methylthio)ethyl]-2-[(3,3,3-trifluoropropyl)thio]-5′-adenylic Acid Monoanhydride with (Dichloromethylene)bis[phosphonic acid]; AR-C 69931; KengrealCAS Number:163706-06-7Molecular Formula:C₁₇H₂₅Cl₂F₃N₅O₁₂P₃S₂Molecular Weight:776.36Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Cangrelor is a P2Y12 inhibitor used as an antiplatelet drug for intravenous application.References:Harrington, R., et al.: New England J. Med., 361, 2318 (2009); van Giezen, J., et al.: Seminars in Thrombosis and Hemostasis, 31, 195 (2005)To ensure the stability of […]
cis-Capsaicin-d3
Chemical Name:cis-Capsaicin-d3Synonyms:(6Z)-N-[(4-Hydroxy-3-(methoxy-d3)phenyl)methyl]-8-methyl-6-nonenamide; (Z)-8-Methyl-N-vanillyl-6-nonenamide-d3; (Z)-8-Methyl-N-vanillyl-6-nonenamide-d3; (Z)-Capsaicin-d3; Civamide-d3; Zucapsaicin-d3;CAS Number:1185237-43-7Alternate CAS #:25775-90-0-unlabelledMolecular Formula:C₁₈H₂₄D₃NO₃Molecular Weight:308.43Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Labelled Capsaicin analogue (C175680). It is used as a tool in neurobiological research. Prototype vanilloid receptor agonist. Topical analgesic.Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in […]
tert-Butyl (3aR,6aR)-Hexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxylate
Chemical Name:tert-Butyl (3aR,6aR)-Hexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxylateSynonyms:(3aR,6aR)-Hexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxylic Acid 1,1-Dimethylethyl EsterCAS Number:370882-39-6Molecular Formula:C₁₁H₂₀N₂O₂Molecular Weight:212.29Category:Building Blocks; Miscellaneous;Applications:tert-Butyl (3aR,6aR)-Hexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxylate is used as a reactant in the preparation of diazabicyclo[3.3.0]octane-substituted pyrazine and pyridine derivatives as potent α4β2 nicotinic acetylcholine receptor ligands.References:Scanio, M., et al.: J. Med. Chem., 54, 7678 (2011);To ensure the stability of our products, the efficient express delivery service will be […]
(S)-5-Bromocoerulescine
Chemical Name:(S)-5-BromocoerulescineSynonyms:(3S)-5-bromo-1′-methylspiro[3H-indole-3,3′-pyrrolidin]-2(1H)-one;CAS Number:1829549-86-1Molecular Formula:C₁₂H₁₃BrN₂OMolecular Weight:281.15Category:Standards; Natural Products;Applications:(S)-5-Bromocoerulescine, is a derivative of Coerulescine, which is an oxindole that can be found in the plant Horsfieldia superba, and it has analgesic effects.References:Jossang, A. et al.: J. Org. Chem. 56 (23): 6527–6530; Lakshmaiah, G. et al.: J. Org. Chem.64 (5): 1699–1704;To ensure the stability of our products, the […]
(3R, 4R)-1-Boc-4-methylpiperidin-3-ol
Chemical Name:(3R, 4R)-1-Boc-4-methylpiperidin-3-olMolecular Formula:C₁₁H₂₁NO₃Molecular Weight:215.29Category:Building Blocks; Miscellaneous;Applications:(3R, 4R)-1-Boc-4-methylpiperidin-3-ol is a useful synthetic compound.To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be […]