Chemical Name:cis-Capsaicin-d3Synonyms:(6Z)-N-[(4-Hydroxy-3-(methoxy-d3)phenyl)methyl]-8-methyl-6-nonenamide; (Z)-8-Methyl-N-vanillyl-6-nonenamide-d3; (Z)-8-Methyl-N-vanillyl-6-nonenamide-d3; (Z)-Capsaicin-d3; Civamide-d3; Zucapsaicin-d3;CAS Number:1185237-43-7Alternate CAS #:25775-90-0-unlabelledMolecular Formula:C₁₈H₂₄D₃NO₃Molecular Weight:308.43Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Labelled Capsaicin analogue (C175680). It is used as a tool in neurobiological research. Prototype vanilloid receptor agonist. Topical analgesic.Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in […]

Chemical Name:5-Carboxymethylaminomethyl-2-thiouridineSynonyms:mcm5S2U;2-(((1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl)amino)acetic acid;N-[(1,2,3,4-Tetrahydro-4-oxo-1-β-D-ribofuranosyl-2-thioxo-5-pyrimidinyl)methyl]glycine; 5-Carboxymethylaminomethyl-2-thiouridineCAS Number:78173-95-2Molecular Formula:C₁₂H₁₇N₃O₇SMolecular Weight:347.34Category:Research Tools; Standards; Molecular Biology; Nucleic Acids; Natural Products;Applications:5-Carboxymethylaminomethyl-2-thiouridine or mcm5S2U, is a naturally occurring 2-thio-modification of tRNA catalyzed by the action of Nfs1 enzyme on cy-tRNALyS2UUU and cy-tRNAGlU3UUCReferences:Nakai, Y., et. al.: J. Biol. Chem., 279, 12363 (2004);Aduri, R., et. al.: J Chem Theor Comput, 3, 1464 (2007)To ensure […]

Chemical Name:(R)-Carbidopa Methyl Ester N-CyclohexylideneSynonyms:(αR)-α-(2-Cyclohexylidenehydrazinyl)-3,4-dihydroxy-α-methylbenzenepropanoic Acid Methyl EsterMolecular Formula:C₁₇H₂₄N₂O₄Molecular Weight:320.38Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:(R)-Carbidopa Methyl Ester N-Cyclohexylidene is an intermediate used in the synthesis of R-(+)-Carbidopa (C175986), which is an inhibitor of DOPA decarboxylase, which plays a significant role in the prevention of the conversion of L-DOPA (D533751) to dopamine (D533780). Studies has also indicated the […]

Chemical Name:N-5-(2-Carbamoyl) Benzofuranyl Vilazodone (Vilazodone Impurity)Molecular Formula:C₃₅H₃₂N₆O₄Molecular Weight:600.67Category:Research Tools;Applications:N-5-(2-Carbamoyl) Benzofuranyl Vilazodone is an impurity of Vilazodone (V265000) which is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist currently under clinical evaluation for the treatment of major depression.References:Bartoszyk, G., et al.: Eur. J. Pharmacol., 322, 147 (19970, Heinrich, T., et al.: J. […]

Chemical Name:1-[[[(1R)-1-[3-[(2S,R)-2-[[(1-Carboxycyclopropyl)methyl]thio]-2-(7-chloro-2-quinolinyl)ethyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methylcyclopropaneacetic AcidSynonyms:Montelukast Impurity;Molecular Formula:C₄₁H₄₆ClNO₅S₂Molecular Weight:732.39Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:1-[[[(1R)-1-[3-[(2S,R)-2-[[(1-Carboxycyclopropyl)methyl]thio]-2-(7-chloro-2-quinolinyl)ethyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methylcyclopropaneacetic Acid is derived from Montelukast Methyl Ester (M568080), which is an impurity of the antiasthmatic drug Montelukast (M568000), a selective leukotriene D4-receptor antagonist. Used as an anti-asthmatic.References:Balani, S., et al.: Drug Metab. Dispos., 25, 1282 (1997); Radhakrishna, T., et al.: Pharm. Biomed. Anal., 31, 359 (2003); […]

Chemical Name:15,15′-cis-β,β-CaroteneSynonyms:15-cis-β,β-Carotene; (15Z)-β,β-Carotene; (15Z)-β-Carotene; 15,15′-cis-β,β-Carotene; 15,15′-cis-β-Carotene;15-cis-β-Carotene;CAS Number:19361-58-1Molecular Formula:C₄₀H₅₆Molecular Weight:536.87Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:15,15′-cis-β,β-Carotene is a very powerful antioxidant and a precursor to Vitamin A which is an essential nutrient, required by the retina of the eye in the form of a specific metabolite, the light-absorbing molecule retinal, that is necessary for both low-light (scotopic vision) and […]

Chemical Name:Carvedilol-13C6Synonyms:1-((9H-Carbazol-4-yl)oxy)-3-((2-(2-methoxyphenoxy-1,2,3,4,5,6-13C6)ethyl)amino)propan-2-olAlternate CAS #:72956-09-3Molecular Formula:C₁₈¹³C₆H₂₆N₂O₄Molecular Weight:412.44Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Carvedilol-13C6 is the labelled form of the compound Carvedilol (CAT# C184625), which is a nonselective β-adrenergic blocker with α1-blocking activity. Carvedilol is an antihypertensive used in the treatment of congestive heart failure.References:Hirohashi, M., et al.: Arzneim.-Forsch., 40, 735 (1990); Packer, M., et al.: N. […]

Chemical Name:Brinzolamide Methanesulfonyl AmideAlternate CAS #:138890-62-7Molecular Formula:C₁₃H₂₃N₃O₇S₄Molecular Weight:461.6Category:Research Tools; Molecular Biology; Enzyme Activators and Inhibitors;Applications:Brinzolamide Methanesulfonyl Amide is an impurity of Brinzolamide (B677600, HCl salt) which is a carbonic anhydrase inhibitor.References:Silver, L.H., et al.: Am. J. Ophthalmol., 126, 400 (1998); Davies, N., et al.: Clin. Exp. Pharmacol. Physiol., 27, 558 (2000); Stave, J., et al.: […]

Chemical Name:(S)-BrinzolamideSynonyms:(S)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-Dioxide, ; AL 4862; Brinzolamide USP Related Compound AImpurityBrinzolamide USP Related Compound ACAS Number:154127-19-2Molecular Formula:C₁₂H₂₁N₃O₅S₃Molecular Weight:383.51Category:Research Tools;Applications:(S)-Brinzolamide is an isomer of Brinzolamide (B677601), Carbonic anhydrase inhibitor. Antiglaucoma agent.References:Silver, L.H., et al.: Am. J. Ophthalmol., 126, 400 (1998), Davies, N., et al.: Clin. Exp. Pharmacol. Physiol., 27, 558 (2000), Stave, J., et al.: Ophthalmologe, […]

Chemical Name:(S)-Brinzolamide (Ethyl-d5)Synonyms:(S)-4-(Ethyl-d5-amino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-Dioxide; AL 4862-d5;Molecular Formula:C₁₂H₁₆D₅N₃O₅S₃Molecular Weight:388.54Category:Building Blocks; Isotopic Labeled Analogues;Applications:(S)-Brinzolamide-d5 is the labeled analogue of (S)-Brinzolamide (B677605), an isomer of Brinzolamide (B677601), a carbonic anhydrase inhibitor. Antiglaucoma agent.References:Silver, L.H., et al.: Am. J. Ophthalmol., 126, 400 (1998); Davies, N., et al.: Clin. Exp. Pharmacol. Physiol., 27, 558 (2000); Stave, J., et al.: Ophthalmologe, […]