Chemical Name:1-(3-Cyanophenyl)-3-((1S,4S)-4-(3,5-dimethyl-1-(4-(trifluoromethyl)phenyl)-1H-pyrazol-4-yl)cyclopent-2-en-1-yl) UreaCAS Number:1175961-96-2Molecular Formula:C₂₅H₂₂F₃N₅OMolecular Weight:465.47Category:Research Tools; Molecular Biology;Applications:1-(3-Cyanophenyl)-3-((1S,4S)-4-(3,5-dimethyl-1-(4-(trifluoromethyl)phenyl)-1H-pyrazol-4-yl)cyclopent-2-en-1-yl) Urea is a useful chemical reagent.To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products […]

Chemical Name:Cdk4/6 Inhibitor IV-labelledAlternate CAS #:359886-84-3Molecular Formula:C₂₇H₂₅D₇N₆OMolecular Weight:463.64Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Cdk4/6 Inhibitor IV-labelled is a deuterium labelled form of Cdk4/6 Inhibitor IV (C228135).To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect […]

Chemical Name:(+)-Calanolide ASynonyms:(10R,11S,12S)-11,12-Dihydro-12-hydroxy-6,6,10,11-tetramethyl-4-propyl-2H,6H,10H-benzo[1,2-b:3,4-b’:5,6-b”]tripyran-2-one; [10R-(10α,11β,12α)]-11,12-Dihydro-12-hydroxy-6,6,10,11-tetramethyl-4-propyl-2H,6H,10H-benzo[1,2-b:3,4-b’:5,6-b”]tripyran-2-one; Calanolide A; NSC 650886CAS Number:142632-32-4Molecular Formula:C₂₂H₂₆O₅Molecular Weight:370.44Category:Research Tools;Applications:(+)-Calanolide A is an experimental non-nucleoside reverse transcriptase inhibitor. It has potent anti-HIV activity.References:Kashman, Y., et al.: J. Med. Chem., 35, 2735 (1992); Jorgensen, W., et al.: Bioorg. Med. Chem. Lett., 16, 663 (2006)To ensure the stability of our products, the efficient express delivery […]

Chemical Name:((4-(7-(2-(4-Chlorophenoxy)ethyl)-2-(methylamino)-6-oxo-6,7-dihydro-3H-purin-8-yl)phenyl)difluoromethyl)phosphonic AcidCAS Number:1373822-46-8Molecular Formula:C₂₁H₁₉ClF₂N₅O₅PMolecular Weight:525.83Category:Building Blocks; Miscellaneous;Applications:((4-(7-(2-(4-Chlorophenoxy)ethyl)-2-(methylamino)-6-oxo-6,7-dihydro-3H-purin-8-yl)phenyl)difluoromethyl)phosphonic Acid is used as an intermediate in the synthesis of guanine-derived inhibitors of eIF4E mRNA-cap interaction.References:Chen, X., et al.: J. Med. Chem., 55, 3837 (2012)To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be […]

Chemical Name:(1S,3R)-3-(5-(5-Chloro-2-ethoxyphenyl)-1,3,4-oxadiazol-2-yl)-N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)cyclohexanecarboxamideCAS Number:1807337-46-7Molecular Formula:C₂₈H₃₀ClN₅O₄Molecular Weight:536.02Category:Building Blocks; Miscellaneous;Applications:(1S,3R)-3-(5-(5-Chloro-2-ethoxyphenyl)-1,3,4-oxadiazol-2-yl)-N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)cyclohexanecarboxamide is a useful intermediate for organic synthesis.To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will […]

Chemical Name:3-(6-Chloropyrimidin-4-yl)-5-(1-methylcyclopropoxy)-2-((2-(trimethylsilyl)ethoxy)methyl)-2H-indazoleCAS Number:1627093-41-7Molecular Formula:C₂₁H₂₇ClN₄O₂SiMolecular Weight:431Category:Building Blocks; Miscellaneous;Applications:3-(6-Chloropyrimidin-4-yl)-5-(1-methylcyclopropoxy)-2-((2-(trimethylsilyl)ethoxy)methyl)-2H-indazole is a useful intermediate in the development of MLi-​2 (3-​(4-​Pyrimidinyl) Indazole), a potent orally available brain penetrant inhibitor of LRRK2.References:Scott, J. D., et al.: J. Med. Chem., 60, 2983 (2017);To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that […]

Chemical Name:CandoxatrilSynonyms:cis-4-[[[1-[(2S)-3-[(2,3-Dihydro-1H-inden-5-yl)oxy]-2-[(2-methoxyethoxy)methyl]-3-oxopropyl]cyclopentyl]carbonyl]amino]cyclohexanecarboxylic Acid; UK 79300;CAS Number:123122-55-4Molecular Formula:C₂₉H₄₁NO₇Molecular Weight:515.64Category:Research Tools;Applications:Neutral endopeptidase inhibitor. Used in treatment of congestive heart failure.References:Motwani, J.G., et al.: Clin. Pharmacol. Ther., 54, 661 (1993), Kimmelstiel, C.D., et al.: Cardiology, 87, 46 (1996),To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products […]

Chemical Name:CangrelorSynonyms:N-[2-(Methylthio)ethyl]-2-[(3,3,3-trifluoropropyl)thio]-5′-adenylic Acid Monoanhydride with (Dichloromethylene)bis[phosphonic acid]; AR-C 69931; KengrealCAS Number:163706-06-7Molecular Formula:C₁₇H₂₅Cl₂F₃N₅O₁₂P₃S₂Molecular Weight:776.36Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Cangrelor is a P2Y12 inhibitor used as an antiplatelet drug for intravenous application.References:Harrington, R., et al.: New England J. Med., 361, 2318 (2009); van Giezen, J., et al.: Seminars in Thrombosis and Hemostasis, 31, 195 (2005)To ensure the stability of […]

Chemical Name:cis-Capsaicin-d3Synonyms:(6Z)-N-[(4-Hydroxy-3-(methoxy-d3)phenyl)methyl]-8-methyl-6-nonenamide; (Z)-8-Methyl-N-vanillyl-6-nonenamide-d3; (Z)-8-Methyl-N-vanillyl-6-nonenamide-d3; (Z)-Capsaicin-d3; Civamide-d3; Zucapsaicin-d3;CAS Number:1185237-43-7Alternate CAS #:25775-90-0-unlabelledMolecular Formula:C₁₈H₂₄D₃NO₃Molecular Weight:308.43Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Labelled Capsaicin analogue (C175680). It is used as a tool in neurobiological research. Prototype vanilloid receptor agonist. Topical analgesic.Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in […]

Chemical Name:5-Carboxymethylaminomethyl-2-thiouridineSynonyms:mcm5S2U;2-(((1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl)amino)acetic acid;N-[(1,2,3,4-Tetrahydro-4-oxo-1-β-D-ribofuranosyl-2-thioxo-5-pyrimidinyl)methyl]glycine; 5-Carboxymethylaminomethyl-2-thiouridineCAS Number:78173-95-2Molecular Formula:C₁₂H₁₇N₃O₇SMolecular Weight:347.34Category:Research Tools; Standards; Molecular Biology; Nucleic Acids; Natural Products;Applications:5-Carboxymethylaminomethyl-2-thiouridine or mcm5S2U, is a naturally occurring 2-thio-modification of tRNA catalyzed by the action of Nfs1 enzyme on cy-tRNALyS2UUU and cy-tRNAGlU3UUCReferences:Nakai, Y., et. al.: J. Biol. Chem., 279, 12363 (2004);Aduri, R., et. al.: J Chem Theor Comput, 3, 1464 (2007)To ensure […]