Messenger RNA (mRNA), a leading edge in current chemical research, plays a key role in recent vaccine development. Previously, the delivery of mRNA through lipid nanoparticles (LNPs) will lead to the accumulation of LNPs in the liver which further limit their access to other organs. Researchers found the targeting LNPs have the ability to deliver […]

In recent years, the research on lipids has become a popular realm to understand various diseases, including cancers, among which Renal Cell Carcinoma (RCC), a kind of common kidney cancers, has attracted significant attention. In order to unravel the intricate relationship between lipids and the development and progress of RCC, researchers explore the lipidome of […]

In recent years, an innovative technique of delivering mRNA to the neural retina has been found for the treatment of inherited retinal degenerations and blindness. Using the peptide-guided lipid nanoparticles (LNPs), scientists have successfully locked on photoreceptor cells in the eyes and achieved the targeted delivery of mRNA to a variety of cell types in […]

As a promising therapeutic reagents delivery method, lipid nanoparticles (LNPs) has brought about a great impact in the pharmaceutical filed. LNPs offer a platform for precise drug delivery and they can be applied in medicine, medical imaging, cosmetics, nutrition, agriculture and other various fields. LNPs are capable of effectively encapsulating and transporting therapeutic payloads, for instance, they can […]