Catalogue Number:B201995
Chemical Name:α-Bromo-1,2-benzisoxazole-3-acetic Acid
Synonyms:2-(1,2-Benzoxazol-3-yl)-2-bromoacetic Acid
CAS Number:37924-67-7
Molecular Formula:C₉H₆BrNO₃
Molecular Weight:256.06
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:α-Bromo-1,2-benzisoxazole-3-acetic Acid is an intermediate in the synthesis of Zonisamide (Z700000); Sulfonamide antiseizure agent; blocks repetitive firing of voltagesensitive sodium channels and reduces voltage-sensitive T-type calcium currents. Heterocyclic methanesulfonide with anticonvulsant properties. The compound is under investigation for potential therapeutic use as an antiepileptic drug. Anticonvulsant. Neuroprotective & Neuroresearch Product.
References:Masuda, Y., et al.: Arzneim.-Forsch., 30, 477 (1980), Hammond, E.J., et al.: Gen. Pharmacol., 18, 303 (1987), Schmidt, D., et al.: Epilepsy Res., 15, 67 (1993), Sorkin, E.M., et al.: Drugs, 45, 760 (1993),
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