Catalogue Number:D235550
Chemical Name:(2R)-2-Deoxy-2-fluoro-2-methyl-β-D-erythro-pentofuranose 3,5-Dibenzoate
CAS Number:1199809-22-7
Molecular Formula:C₂₀H₁₉FO₆
Molecular Weight:374.36
Category:Research Tools; Standards; Molecular Biology; Enzyme Activators and Inhibitors;
Applications:(2R)-2-Deoxy-2-fluoro-2-methyl-β-D-erythro-pentofuranose 3,5-Dibenzoate has been employed in a study to investigate potent inhibitors against CD38 NADase, an enzyme involved with the metabolism of nicotinamide and calcium signalling pathway. It also has utility in the stereoselective synthesis of β-D-2′-Deoxy-2′-α-fluoro-2′-β-C-methyl-3′,5′-cyclic phosphate nucleotide, a prodrug for treating hepatitis C virus (HCV) infection.
References:Wang, S., et al.: Molecules 19, 15754 (2014); Reddy, P. G., et al.: J. Org. Chem. 76, 3782 (2011)
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