Chemical Name:α-Dihydrotetrabenazine-D7Synonyms:(2R,3R,11bR)-3-Isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-ol-D7Alternate CAS #:85081-18-1Molecular Formula:C₁₉H₂₂D₇NO₃Molecular Weight:326.48Applications:α-Dihydrotetrabenazine-D7 is an isotopic analogue form of (+)-α-Dihydrotetrabenazine(D453615). (+)-α-Dihydrotetrabenazine is a potent inhibitor of vascular monoamine transporter 2 (VMAT2) and an agent of significant interest for therapeutic and molecular imaging applications.References:Yao, Z., et al.: Eur. J. Med. Chem., 46, 1841 (2011); Rishel, M.J., et al.: J. Org. Chem., 74, 4001 […]

Chemical Name:(+)-β-Dihydrotetrabenazine-13C2D6Synonyms:(2S,3R,11bR)-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-ol-13C2D6; (2S,3R,11bR)-Dihydrotetrabe-13C2D6Alternate CAS #:Unlabelled: 924854-60-4Molecular Formula:C₁₇¹³C₂H₂₃D₆NO₃Molecular Weight:327.46Category:Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:(+)-β-Dihydrotetrabenazine-13C2D6 is the isotope labelled analog of (+)-β-Dihydrotetrabenazine (D453610); a potent inhibitor of vascular monoamine transporter 2 (VMAT2) and an agent of significant interest for therapeutic and molecular imaging applications.References:Yao, Z., et al.: Eur. J. Med. Chem., 46, […]

Chemical Name:β-Dihydrotetrabenazine-D7Synonyms:(2S,3R,11bR)-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-ol-D7Alternate CAS #:924854-60-4Molecular Formula:C₁₉H₂₂D₇NO₃Molecular Weight:326.48Applications:β-Dihydrotetrabenazine-D7 is an isotopic labeled analogue of (+)-β-Dihydrotetrabenazine(D453610). (+)-β-Dihydrotetrabenazine is a potent inhibitor of vascular monoamine transporter 2 (VMAT2) and an agent of significant interest for therapeutic and molecular imaging applications.References:Yao, Z., et al.: Eur. J. Med. Chem., 46, 1841 (2011); Rishel, M.J., et al.: J. Org. Chem., 74, 4001 […]

Chemical Name:N-[(3β,7α,12α)-7,12-Dihydroxy-24-oxo-3-(sulfooxy)chol-5-en-24-yl]glycine-13C2,15N Disodium SaltAlternate CAS #:Unlabelled: 1638974-22-7; Unlabelled Free Base: 14Molecular Formula:C₂₄¹³C₂H₃₉¹⁵NNa₂O₉SMolecular Weight:590.61Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Steroids;Applications:N-[(3β,7α,12α)-7,12-Dihydroxy-24-oxo-3-(sulfooxy)chol-5-en-24-yl]glycine-13C2,15N Disodium Salt is the labeled form of N-[(3β,7α,12α)-7,12-Dihydroxy-24-oxo-3-(sulfooxy)chol-5-en-24-yl]glycine Disodium Salt (D452645), which is derived from Cholic Acid (C432600) that is produced by, and isolated from liver cells.References:Nomoto, M., et al.: Biol. Pharm. Bull., 32, 172 (2009), Simonsen, H., […]

Chemical Name:N-[(3β,7α,12α)-7,12-Dihydroxy-24-oxo-3-(sulfooxy)chol-5-en-24-yl]glycine Disodium SaltCAS Number:1638974-22-7Alternate CAS #:Free Base: 1427772-30-2Molecular Formula:C₂₆H₃₉NNa₂O₉SMolecular Weight:587.63Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Steroids;Applications:N-[(3β,7α,12α)-7,12-Dihydroxy-24-oxo-3-(sulfooxy)chol-5-en-24-yl]glycine Disodium Salt is derived from Cholic Acid (C432600), which is produced by, and isolated from liver cells.References:Nomoto, M., et al.: Biol. Pharm. Bull., 32, 172 (2009), Simonsen, H., et al.: J. Agric. Food Chem., 57, 2056 (2009), Miyata, M., et […]

Chemical Name:erythro-β,3-Dihydroxy-L-tyrosineSynonyms:Serine, 3-(3,4-dihydroxyphenyl)-, L-erythro- (8CI); (βS)-β,3-Dihydroxy-L-tyrosine; (+)-erythro-3,4-Dihydroxyphenylserine; L-erythro-3,4-DihydroxyphenylserineL-erythro-3-(3,4-Dihydroxyphenyl)serine; erythro-Dopaserine; L-Tyrosine, β,3-dihydroxy-, (βS)-;CAS Number:34047-62-6Molecular Formula:C₉H₁₁NO₅Molecular Weight:213.19Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:erythro-β,3-Dihydroxy-L-tyrosine administered to rats inhibited the methamphetamins-induced locomotor activity and decreased the brain dopamine content.References:Harada, H., et al.: Yakubutsu Seishin Kodo., 11, 403 (1991)To ensure the stability of our products, the efficient express delivery service will be used. […]

Chemical Name:erythro-β,3-Dihydroxy-D-tyrosineSynonyms:(-)-erythro-3,4-Dihydroxyphenylserine; D-erythro-3,4-DihydroxyphenylserineCAS Number:51829-98-2Molecular Formula:C₉H₁₁NO₅Molecular Weight:213.19Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:erythro-β,3-Dihydroxy-D-tyrosine as an adrenergic pro-drug. Bioactivation of erythro-β,3-Dihydroxy-D-tyrosine to the potent pharmacological agent, noradrenalone (arterenone), via sequential stereoselective action by two target enzymes – dopamine β-monooxygenase (DBM) and L-arom. amino acid decarboxylase (AADC) – acting in tandem.References:Debnath, J., et al.: Biochem. Biophys. Res. Commun., 189, 33-9 (1992)To […]

Chemical Name:7β,25-DihydroxycholesterolSynonyms:3β,7β,25-Trihydroxycholest-5-ene; (3β,7β)-Cholest-5-ene-3,7,25-triol;CAS Number:64907-21-7Molecular Formula:C₂₇H₄₆O₃Molecular Weight:418.65Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Steroids;Applications:7β,25-Dihydroxycholesterol is a potent and selective agonist of EB12. This compound can be used as a drug delivery system containing oxidized cholesterol.References:Hannedouche, Sebastien., Nature (London, United Kingdom), 475, 524-527, (2011); Dahlman, J., et.al., PCT Int. Appl., 63, (2020);To ensure the stability of our products, the efficient […]

Chemical Name:Dihydro Idebenone 4-Sulfate 1-Glucuronide Dipotassium SaltMolecular Formula:C₂₅H₃₈K₂O₁₄SMolecular Weight:672.82Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Dihydro Idebenone 4-Sulfate 1-Glucuronide Dipotassium Salt is derived from Idebenone (I170050), which is a ubiquinone derivative with protective effects against cerebral ischemia. This compound has neuroprotective and nootropic properties.References:Barkworth, M.F., et al.: Arzneim.-Forsch., 35, 1704 (1985), Kobayashi, T., et al.: J. Pharmacobio-Dyn., 8, 448 […]

Chemical Name:(1R,2S)-rel-2-(2,3-Dihydro-4-benzofuranyl)-cyclopropanemethanamineSynonyms:(1R,​2S)​-​rel-2-​(2,​3-​Dihydro-​4-​benzofuranyl)​-​, Cyclopropanemethanam​ine,CAS Number:251562-77-3Molecular Formula:C₁₂H₁₅NOMolecular Weight:189.25Category:Building Blocks; Miscellaneous;Applications:(1R,2S)-rel-2-(2,3-Dihydro-4-benzofuranyl)-cyclopropanemethanamine is used in the preparation of pharmaceuticals as melatonin receptor agonists.References:Chen, J. et al.: PCT Int. Appl. (1999), WO 9962515 A1 19991209To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the […]