Chemical Name:LumateperoneSynonyms:1-(4-fluorophenyl)-4-[(6bR,10aS)-3-methyl-2,3,6b,9,10,10a-hexahydro-11H-pyrido[3′,4′:4,5]pyrrolo[1,2,3-de]quinoxalin-8(7H)-yl]butan-1-one; ITI 007; 1-(4-Fluorophenyl)-4-[(6bR,10aS)-2,3,6b,9,10,10a-hexahydro-3-methyl-1H-pyrido[3′,4′:4,5]pyrrolo[1,2,3-de]quinoxalin-8(7H)-yl]-1-butanoneCAS Number:313368-91-1Molecular Formula:C₂₄H₂₈FN₃OAppearance:Light Brown to Brown Thick OilMolecular Weight:393.5Solubility:DMSO (Slightly), Methanol (Very Slightly)Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Lumateperone was a drug developed for the treatment of schizophrenia. May have applications in bipolar depression.References:Corponi, F., et al.: Eur. Neuropsychopharmacol., 29, 971-985 (2019)To ensure the stability of our products, the efficient express delivery service will […]

Chemical Name:LY2562175Synonyms:6-[4-[[5-Cyclopropyl-3-(2,6-dichlorophenyl)-4-isoxazolyl]methoxy]-1-piperidinyl]-1-methyl-1H-indole-3-carboxylic Acid; LY-2562175CAS Number:1103500-20-4Molecular Formula:C₂₈H₂₇Cl₂N₃O₄Molecular Weight:540.44Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:LY2562175, is a potent and selective FXR agonist with an EC50 of 193 nM.References:Genin, M. J. et al.: J. Med. Chem., 58, 9768 (2015).To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be […]

Chemical Name:LY 311727Synonyms:P-[3-[[3-(2-Amino-2-oxoethyl)-2-ethyl-1-(phenylmethyl)-1H-indol-5-yl]oxy]propyl]phosphonic Acid; [3-[[3-(2-Amino-2-oxoethyl)-2-ethyl-1-(phenylmethyl)-1H-indol-5-yl]oxy]propyl]phosphonic Acid; [3-[[3-(Amidomethyl)-2-ethyl-1-(phenylmethyl)indol-5-yl]oxy]propyl]phosphonic AcidCAS Number:164083-84-5Molecular Formula:C₂₂H₂₇N₂O₅PMolecular Weight:430.43Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:LY 311727 is an inhibitor of secretory phospholipase A2 (sPLA2) and can be used to block Pseudomonas aeruginosa cytotoxicity. It can also attenuate VEGF-mediated platelet-activating factor (PAF) synthesis in HUVEC and BAEC cells.References:Phillips, R., et al.: J. Biol. […]

Chemical Name:LY 3009120Synonyms:N-(3,3-Dimethylbutyl)-N’-[2-fluoro-4-methyl-5-[7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl]phenyl]urea;CAS Number:1454682-72-4Molecular Formula:C₂₃H₂₉FN₆OMolecular Weight:424.51Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:LY 3009120 is a potent pan-Rad inhibitor used in the inhibition of tumors. Dose-dependant inhibition.References:Henry, J. et al.: J. Med. Chem., 58, 4165 (2015);To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped […]

Chemical Name:Lucifer Yellow VS Dilithium SaltSynonyms:6-Amino-2-[3-(ethenylsulfonyl)phenyl]-2,3-dihydro-1,3-dioxo-1H-benz[de]isoquinoline-5,8-disulfonic Acid Dilithium SaltCAS Number:71231-14-6Alternate CAS #:Free Base: 107014-64-2Molecular Formula:C₂₀H₁₄N₂O₁₀S₃ •2LiMolecular Weight:538.53+2(6.94)Category:Research Tools; Materials; Dyes;Applications:Lucifer Yellow VS Dilithium Salt is a highly fluorescent dye used for labeling proteins. It can also be used in analytical study of dual analyte flow injection fluorescence immunoassays using thiophilic gel reactors and synchronous scanning […]

Chemical Name:11-epi LubiprostoneMolecular Formula:C₂₀H₃₂F₂O₅Molecular Weight:390.46Category:Building Blocks; Miscellaneous;Applications:11-epi Lubiprostone is an analog of Lubiprotone (L473500). Lubiprostone is a bicyclic fatty acid metabolite analog of Prostaglandin E1. It activates specific chloride channels in the gastrointestinal tract to stimulate intestinal fluid secretion, increase gastrointestinal transit, and improve symptoms of constipation.References:Farthing, M., et al.: Drugs, 56, 11 (1998), Pare, […]

Chemical Name:12-epi LubiprostoneMolecular Formula:C₂₀H₃₂F₂O₅Category:Building Blocks; Miscellaneous;Applications:12-epi Lubiprostone is an analog of Lubiprostone (L473500). Lubiprostone is a bicyclic fatty acid metabolite analog of Prostaglandin E1. It activates specific chloride channels in the gastrointestinal tract to stimulate intestinal fluid secretion, increase gastrointestinal transit, and improve symptoms of constipation.References:Farthing, M., et al.: Drugs, 56, 11 (1998), Pare, P., […]

Chemical Name:8-epi LubiprostoneMolecular Formula:C₂₀H₃₂F₂O₅Molecular Weight:390.46Category:Building Blocks; Miscellaneous;Applications:8-epi Lubiprostone is an analog of Lubiprostone (L473500). Lubiprostone is a bicyclic fatty acid metabolite analog of Prostaglandin E1. It activates specific chloride channels in the gastrointestinal tract to stimulate intestinal fluid secretion, increase gastrointestinal transit, and improve symptoms of constipation.References:Farthing, M., et al.: Drugs, 56, 11 (1998), Pare, […]

Chemical Name:Lorazepam-13C6CAS Number:N/AMolecular Formula:C913C6H10Cl2N2O2Molecular Weight:327.11Applications:Lorazepam-13C6 is a useful research chemical compound.To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be wrapped with […]

Chemical Name:LY 3039478Synonyms:N-[(1S)-2-[[(7S)-6,7-Dihydro-5-(2-hydroxyethyl)-6-oxo-5H-pyrido[3,2-a][3]benzazepin-7-yl]amino]-1-methyl-2-oxoethyl]-4,4,4-trifluorobutanamide; Crenigacestat;CAS Number:1421438-81-4Molecular Formula:C₂₂H₂₃F₃N₄O₄Molecular Weight:464.44Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:LY 3039478 is used in the preparation of medicaments for combination antitumor therapy with Notch and PD-1 or PD-Li inhibitors.References:Bender, M. H., et al.: From PCT Int. Appl. (2017), WO 2017200969 A1 20171123To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that […]