Chemical Name:(R)-Carbidopa Methyl Ester N-Cyclohexylidene
Synonyms:(αR)-α-(2-Cyclohexylidenehydrazinyl)-3,4-dihydroxy-α-methylbenzenepropanoic Acid Methyl Ester
Molecular Formula:C₁₇H₂₄N₂O₄
Molecular Weight:320.38
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(R)-Carbidopa Methyl Ester N-Cyclohexylidene is an intermediate used in the synthesis of R-(+)-Carbidopa (C175986), which is an inhibitor of DOPA decarboxylase, which plays a significant role in the prevention of the conversion of L-DOPA (D533751) to dopamine (D533780). Studies has also indicated the inhibitory effects of towards L-DOPA in human liver prepns and as well as 5-hydroxytryptophan (H975700).
References:Vogel, W.H. et al.: Arch. Int. Pharmacodyn. Ther. 198, 85 (1972);
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