Chemical Name:AZ 10417808
Synonyms:2-[(3,4-Dichlorophenyl)amino]-1,4-dihydro-6-nitro-4-oxo-N-2-propenyl-8-quinazolinecarboxamide; 2-[(3,4-Dichlorophenyl)amino]-1,4-dihydro-6-nitro-4-oxo-N-2-propenyl-8-quinazolinecarboxamide (9CI)
CAS Number:331645-84-2
Molecular Formula:C₁₈H₁₃Cl₂N₅O₄
Molecular Weight:434.23
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:AZ 10417808 inhibits human caspase-3 with Ki values in the 90 to 800 nM range. AZ 10417808 blocks cellular and biochemical features of apoptosis in cells.
References:Scott, C.W.; et al.: J. Pharmacol. Exp. Ther., 304, 433 (2003)
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