Catalogue Number:C240800
Chemical Name:Ivosidenib Isonicotinamide
Synonyms:2-((S)-2-(((S)-1-(2-Chlorophenyl)-2-((3,3-difluorocyclobutyl)amino)-2-oxoethyl)(5-fluoropyridin-3-yl)carbamoyl)-5-oxopyrrolidin-1-yl)isonicotinamide
CAS Number:2408269-64-5
Molecular Formula:C₂₈H₂₄ClF₃N₆O₄
Molecular Weight:600.98
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Ivosidenib 5-Oxopyrrolidin-1-yl Isonicotinamide is a derivative of Ivosidenib (I940940(P)), which is a first-in-class mutant IDH1 inhibitor for the treatment of IDH1 mutant cancers.
References:Popovici-Muller, J., et al.: ACS Medicinal Chemistry Letters, 9, 300 (2018);
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