1-(4-Hydroxyphenyl)-2-chloroethanol

Chemical Name:1-(4-Hydroxyphenyl)-2-chloroethanol
Synonyms:α-(Chloromethyl)-p-hydroxy-benzyl Alcohol; α-(Chloromethyl)-4-hydroxy-benzenemethanol
CAS Number:4973-17-5
Molecular Formula:C₈H₉ClO₂
Molecular Weight:172.61
Category:Building Blocks; Miscellaneous;
Applications:1-(4-Hydroxyphenyl)-2-chloroethanol is synthesized from 2-Chloro-1-(4-hydroxy-phenyl)-ethanone. 2-Chloro-1-(4-hydroxy-phenyl)-ethanone is a reagent that is used in the preparation of hydroxypyrimidine derivatives and their HDAC (histone deacetylases) inhibitory activity.
References:Kemp, M.M., et al.: Bioorg. Med. Chem. Lett., 21, 4164 (2011)
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