Fulvestrant 17-Ketone-D2

Chemical Name:Fulvestrant 17-Ketone-D2
Synonyms:(7α)-3-Hydroxy-7-[9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl]estra-1,3,5(10)-trien-17-one-D2;
Alternate CAS #:403656-89-3
Molecular Formula:C₃₂H₄₃D₂F₅O₃S
Molecular Weight:606.77
Category:Building Blocks; Chiral Molecules; Steroids; Isotopic Labeled Analogues;
Applications:Fulvestrant 17-Ketone-D2 is an intermediate used in the synthesis of Fulvestrant-d3 (F862502), which is novel labelled steroidal estrogen antagonist reported to lack any partial agonist activity. Antineoplastic (hormonal).
References:Wakeling, A.E., et al.: Cancer Res., 51, 3867 (1991), Howell, A., et al.: Br. J. Cancer, 74, 300 (1996), Robertson, J.F., et al.: Cancer Res., 61, 6739 (2001),
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