1-Ethyl-2-hydroxymethylbenzimidazole-d5

Chemical Name:1-Ethyl-2-hydroxymethylbenzimidazole-d5
Synonyms:1-Ethyl-2-benzimidazolemethanol-d5
Alternate CAS #:unlabelled:21269-78-3;
Molecular Formula:C₁₀H₇D₅N₂O
Molecular Weight:181.25
Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:1-Ethyl-2-hydroxymethylbenzimidazole-d5 is the labelled analogue of 1-Ethyl-2-hydroxymethylbenzimidazole (E917690) which is an intermediate used in the synthesis of N-pyrimidinyl-4-aminobenzenesulfonamides useful for treatment or prevention of disease mediated by α2B-adrenoceptor. It is also used to prepare benzimidazole derivatives as ENaC blockers.
References:Joutsamo, T., et al.: PCT Int. Appl., WO 2003008387 A1 20030130 (2003); Laine, D., et al.: PCT Int. Appl., WO 2011079087 A1 20110630 (2011)
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