3-​[(Ethenylmethoxyphos​phinyl)​oxy]​-phenylmethyl Ester Benzeneacetic Acid

Chemical Name:3-​[(Ethenylmethoxyphos​phinyl)​oxy]​-phenylmethyl Ester Benzeneacetic Acid
Synonyms:Benzyl 2-(3-((Methoxy(vinyl)phosphoryl)oxy)phenyl)acetate
CAS Number:1381994-71-3
Molecular Formula:C₁₈H₁₉O₅P
Molecular Weight:346.31
Category:Building Blocks; Miscellaneous; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:3-​[(Ethenylmethoxyphos​phinyl)​oxy]​-phenylmethyl Ester Benzeneacetic Acid is an intermediate in the synthesis of Nahlsgen (N497063) which is a highly selective, and irreversible γ-​glutamyl transpeptidase (GGT) inhibitor with no inhibitory activity on glutamine amidotransferases.
References:Yamamoto, S., et al.: J. Pharmacol. Exp. Ther., 339, 945 (2011); Tuzova, M., et al.: Front Pharmacol., 5, 1, 2014
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