Chemical Name:(+)-Loline Dihydrochloride
Synonyms:Loline Dihydrochloride; [2R-(2α,3α,3aβ,4α,6aβ)]-Hexahydro-N-methyl-2,4-methano-4H-furo[3,2-b]pyrrol-3-amine Dihydrochloride; (2R,3R,3aS,6aS)-Hexahydro-N-methyl-2,4-methano-4H-furo[3,2-b]pyrrol-3-amine Dihydrochloride;
CAS Number:25161-92-6
Alternate CAS #:Free Base: 25161-91-5
Molecular Formula:C₈H₁₄N₂O • 2HCl
Appearance:Oil
Molecular Weight:154.21 + (36.46)
Solubility:Methanol, Water
Category:Standards; Chiral Molecules; Natural Products;
Applications:(+)-Loline Dihydrochloride is an alkaloid isolated from fungal endophytes, an endosymbiont that lives within a plant. Loline alkaloids were found to provide protection of host plants from aphids herbivory and environmental stresses such as drought and spatial competition.
References:Cakmak, M., et al.: Nature. Chem., 3, 543 (2011); Wilkinson, H.H., et al.: Mol. Plant. Microbe. Interact., 13, 1027 (2000);
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