Chemical Name:2-Hydroxy-3-methylcholanthrene
Synonyms:3-Methyl-2-cholanthrenol (7CI, 8CI); 1,2-Dihydro-3-methylbenz[j]aceanthrylen-2-ol; 3-Methylcholanthren-2-ol
CAS Number:3308-64-3
Alternate CAS #:Parent compound: 56-49-5
Molecular Formula:C₂₁H₁₆O
Molecular Weight:284.35
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:2-Hydroxy-3-methylcholanthrene is a metabolite of 3-Methylcholanthrene, which is formed by liver microsomes in rats. The metabolism of the racemic mixture of 2-Hydroxy-3-methylcholanthrene was found to be enantiospecific; the rate of metabolism of the R isomer is faster than that of the S isomer.
References:Shou, M.; et al.: Carcinogenesis, 11, 933 (1990)
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