trans-4-Hydroxy-L-proline-d6

Chemical Name:trans-4-Hydroxy-L-proline-d6
Synonyms:(-)-4-Hydroxy-2-pyrrolidinecarboxylic Acid-d6; (2S,4R)-(-)-4-Hydroxyproline-d6; (R)-4-Hydroxy-(S)-proline-d6; 4(R)-Hydroxy-2(S)-pyrrolidinecarboxylic Acid-d6; 4-trans-Hydroxy-L-proline-d6; L-Hypro-d6; NSC 46704-d6;
Alternate CAS #:unlabelled: 51-35-4
Molecular Formula:C₅H₃D₆NO₃
Molecular Weight:137.17
Category:Building Blocks; Isotopic Labeled Analogues;
Applications:trans-4-Hydroxy-L-proline-d9 is deuterium labelled trans-4-Hydroxy-L-proline (H952376). A natural constituent of animal structural proteins such as collagen and elastin. Several microorganisms producing proline trans-4- and cis-3-hydroxylase were discovered and these enzymes were applied to the industrial production of trans-4- and cis-3-hydroxy-L-proline.
References:Langmaier, F. et al.: Int. J. Cosm. Sci., 24, 273 (2002); Lawrence, C., et al.: Biochem. J., 313, 185 (1996); Mori, H., et al.: J. Bacteriol.; 179, 5677 (1997); Clifton, I., et al.: Eur. J. Biochem.,  268, 6625 (2001)
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