Chemical Name:Hydrolyzed Ombitasvir
Molecular Formula:C₅₀H₆₉N₇O₉
Molecular Weight:912.12
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Hydrolyzed Ombitasvir is an impurity of Ombitasvir (O633200), which is a pharmaceutical drug that is used in the treatment of hepatitis C virus in patients with HCV genotype 1 infection. Ombitasvir inhibits an important viral phosphoprotein, NS5A, which is involved in viral replication, assembly, and secretion.
References:Feld, J.J., et al.: New Eng. J. Med., 370, 1594 (2014); Lawitz, E., et al.: J. Hepatol., 57, 24 (2012); Afdhal, N., et al.: New England J. Med., 370, 1889 (2014)
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