Chemical Name:3-Ethyl Cefadroxil-d4
Alternate CAS #:Unlabelled CAS# N/A
Molecular Formula:C₁₇H₁₅D₄N₃O₅S
Molecular Weight:381.44
Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:3-Ethyl Cefadroxil-d4 is an isotope analog of 3-Ethyl Cefadroxil and 3-ethyl cefadroxil is a metabolite of 3(6R,7R)-Hydroxy-8-oxo-7-[(2-phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid diphenylmethyl ester. 3(6R,7R)-Hydroxy-8-oxo-7-[(2-phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Diphenylmethyl Ester is a useful synthetic intermediate. It was used to prepare cephalosporin-derived inhibitors. It can also be used to synthesize Ceftaroline Fosamil which is a cephalosporin antibiotic.
References:Buynak, J., et al.: Bioorg. Med. Chem. Lett., 12, 1663 (2002); Kanafani, Z., et al.: Future Microbiology, 4, 25 (2009); Parish, D,, et al.: Curr. Opinion Invest. Drugs, 9, 201 (2000)
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