Ethylbis(de((3R,3aS,6aR)-3-methoxyhexahydrofuro[2,3-b]furan)darunavir)

Chemical Name:Ethylbis(de((3R,3aS,6aR)-3-methoxyhexahydrofuro[2,3-b]furan)darunavir)
Synonyms:N1-((2R,3S)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)-N4-((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)succinamide
Molecular Formula:C₄₄H₆₀N₆O₈S₂
Molecular Weight:865.11
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Ethylbis(de((3R,3aS,6aR)-3-methoxyhexahydrofuro[2,3-b]furan)darunavir) is an impurity of Darunavir (D193500), a second generation HIV-1-protease inhibitor; structurally similar to amprenavir. Antiviral. It is a COVID19-related research product.
References:Koh, Y., et al.: Antimicrob. Agents Chemother., 47, 3123 (2003); Arasteh, K., et al.: AIDS, 19, 943 (2005); Surleraux, D.L.N.G., et al.: J. Med. Chem., 48, 1813 (2005)
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