Chemical Name:(rac-Enterolactone)-O-glucuronide (Mixture of Diastereomers)
Synonyms:3-[[Tetrahydro-4-[(3-hydroxyphenyl)methyl]-2-oxo-3-furanyl]methyl]phenyl-β-D-glucopyranosiduronic Acid; (2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-(3-((4-(3-hydroxybenzyl)-2-oxotetrahydrofuran-3-yl)methyl)phenoxy)tetrahydro-2H-pyran-2-carboxylic Acid
CAS Number:768385-57-5
Molecular Formula:C₂₄H₂₆O₁₀
Molecular Weight:474.46
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Carbohydrates and Oligosaccharides;
Applications:(rac-Enterolactone)-O-glucuronide is the oxidative metabolite of rac Enterolactone (E558950), a metabolite of sesame lignans (sesamin, sesamolin). Inhibits colonic cancer cell growth by inducing cell cycle arrest and apoptosis. Possible relationship between exposure and reduced risk of breast cancer.
References:Dean, B., et. al.: Arch. Biotchem. Biophys., 429, 244 (2004); Ayella, A. et al.: Nut. Res., 30, 762 (2010); Pianjing, P. et al.: J. Agric. Food Chem., 59, 212 (2011); Buck, K. et al.: Am. J. Clinic. Nut., 92, 141 (2010)
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