5,5-Dimethyl-3-(2-((7-methyl-2H-spiro[benzofuran-3,1′-cyclopropan]-4-yl)oxy)pyrimidin-5-yl)imidazolidine-2,4-dione

Chemical Name:5,5-Dimethyl-3-(2-((7-methyl-2H-spiro[benzofuran-3,1′-cyclopropan]-4-yl)oxy)pyrimidin-5-yl)imidazolidine-2,4-dione
Synonyms:Kv3 Modulator 1
CAS Number:1380696-64-9
Molecular Formula:C₂₀H₂₀N₄O₄
Molecular Weight:380.4
Category:Research Tools; Molecular Biology; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:5,5-Dimethyl-3-(2-((7-methyl-2H-spiro[benzofuran-3,1′-cyclopropan]-4-yl)oxy)pyrimidin-5-yl)imidazolidine-2,4-dione is a hydantoin derivative that functions as a Kv3 inhibitor for the treatment of pain and acute noise-induced hearing loss.
References:Large, C.: From PCT Int. Appl. (2013), WO 2013175211 A1 20131128, Large, C., et al.: From PCT Int. Appl. (2017), WO 2017098254 A1 20170615
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