3,4-Difluorophenyl Evogliptin Tartrate

Chemical Name:3,4-Difluorophenyl Evogliptin Tartrate
Synonyms:(R)-4-{(R)-3-amino-4-(3,4-difluorophenyl)butanoyl}-3-(tbutoxymethyl)piperazin-2-one L-tartrate
Molecular Formula:C₁₉H₂₇F₂N₃O₃ • (C₄H₆O₆)
Molecular Weight:383.43 + (150.09)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:3,4-Difluorophenyl Evogliptin Tartrate is an impurity of Evogliptin Tartrate (E945915) which is a useful intermediate used in the preparation of dipeptidyl peptidase-IV inhibitors and derivatives for the treatment of type 2 diabetes.
References:Kim, J., et al.: Bioorg. Med. Chem. Lett., 21, 3809 (2011); Kwak, W. Y., et al.: PCT Int. Appl. (2010), WO 2010114292 A2 20101007
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