Chemical Name:2,6-Dihydroxymethyl Rilpivirine
Molecular Formula:C₂₂H₁₈N₆O₂
Molecular Weight:398.42
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:2,6-Dihydroxymethyl Rilpivirine is used in the preparation of hydrogels used in live cell encapsulation and release. An analog of Rilpivirine (R509800) a novel non-nucleoside reverse transcriptase inhibitor. Rilpivirine seems to be well tolerated with less CNS disturbance than Efavirenz, and has non-teratogenic potential. An anti-HIV agent.
References:Sun, et al.: J. Med. Chem., 41, 4648 (1998), Kashiwada, et al.: Bioorg. Med. Chem. Lett., 11, 183 (2001); Griffin, D. et al.: J. Am. Chem. Soc., 134, 13103 (2012);
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