Benzyl 6-((1R,5R,6S)-1,6-Dihydroxy-8-oxa-3-azabicyclo[3.2.1]octan-3-yl)hexanoate

Chemical Name:Benzyl 6-((1R,5R,6S)-1,6-Dihydroxy-8-oxa-3-azabicyclo[3.2.1]octan-3-yl)hexanoate
Molecular Formula:C₁₉H₂₇NO₅
Molecular Weight:349.42
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Benzyl 6-((1R,5R,6S)-1,6-Dihydroxy-8-oxa-3-azabicyclo[3.2.1]octan-3-yl)hexanoate is an intermediate in synthesizing (6R,7R,8a-rac)-(5”-Desamino Glucosepane (D288468), a derivative of Glucosepane, which is a structurally complex protein posttranslational modification that is believed a exist in all living organisms. Research in humans suggests that glucosepane plays a critical role in the pathophysiology of both diabetes and human aging.
References:Draghici, C., et al.: Science, 350, 294 (2015)
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