Chemical Name:(R)-4-(2-((6-((2,6-Dichlorobenzyl)oxy)hexyl)amino)-1-hydroxyethyl)-2-(hydroxymethyl)phenol
Molecular Formula:C22H29Cl2NO4
Molecular Weight:442.38
Applications:(R)-4-(2-((6-((2,6-Dichlorobenzyl)oxy)hexyl)amino)-1-hydroxyethyl)-2-(hydroxymethyl)phenol is an impurity of Vilanterol (V260000, Trifenatate), a long-acting β2 adrenergic receptor Agonist. It demonstrates prolonged bronchodilation in subjects with asthma and COPD.
References:Procopiou, P., et al.: J. Med. Chem., 53, 4522 (2010); Kempsford, R., et al.: Pulm. Pharmacol. Ther., 26, 256 (2013)
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