Chemical Name:α-Hydroxy Trimethoprim Glucuronide
Synonyms:(2S,3S,4S,5R,6R)-6-((2,4-Diaminopyrimidin-5-yl)(3,4,5-trimethoxyphenyl)methoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid
Alternate CAS #:738-70-5
Molecular Formula:C₂₀H₂₆N₄O₁₀
Molecular Weight:482.45
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:α-Hydroxy Trimethoprim Glucuronide is a related compound of α-Hydroxy Trimethoprim (CAT# H971985), which is a metabolite of Trimethoprim (CAT# T795615). Trimethoprim is an antibiotic used in the treatment of urinary tract infection.
References:Nolte, W. M., et al.: Med. Chem. Res., 29, 1238 (2020); Liu, Z., et al.: Biomed. Chromatogr., 26, 1101 (2012); Gupta, K., et al.: Eur. J. Biomed. Pharm. Sci., 7, 91 (2020); Drekonja, D. M., et al.: JAMA, J. Am. Med. Assoc., 326, 324 (2021)
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