CAS:66600-13-3|1,3-Bis([1,1’-Biphenyl]-4-ylphenylmethyl)-1H-imidazolium Chloride

Catalogue Number:B412700
Chemical Name:1,3-Bis([1,1’-Biphenyl]-4-ylphenylmethyl)-1H-imidazolium Chloride
Synonyms:Bifonazole EP Impurity D
Impurity:Bifonazole EP Impurity D
CAS Number:66600-13-3
Molecular Formula:C₄₁H₃₃ClN₂
Appearance:Off-White to Pale Pink Solid
Melting Point:>121ºC (dec.)
Molecular Weight:589.17
Storage:4°C
Solubility:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:1,3-Bis([1,1’-Biphenyl]-4-ylphenylmethyl)-1H-imidazolium Chloride (Bifonazole EP Impurity D) is a Bifonazole (B383400), an anti-fungal agent used in the treatment of skin diseases. Causes an increase in Ca2+ concentration and triggers cell death in PC3 human prostate cancer cells.
References:Cheng, J. et al.: J. Recep. Sign. Transduct., 34, 493 (2014); Chen, Z. et al.: Mol. Pharm., 12, 590 (2015);
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