Catalogue Number:B410505
Chemical Name:N,N’-Bis(1,4-benzodioxane-2-carbonyl)piperazine
Synonyms:1,4-Bis[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]-piperazine; USP Doxazosin Related Compound F; Doxazosin EP Impurity C
Impurity:Doxazosin EP Impurity C
CAS Number:617677-53-9
Molecular Formula:C₂₂H₂₂N₂O₆
Appearance:White to Pale Beige Solid
Melting Point:> 150°C (Dec)
Molecular Weight:410.42
Storage:-20°C
Solubility:Chloroform (Slightly), Dichloromethane (Slightly)
Category:Building Blocks;
Applications:N,N’-Bis(1,4-benzodioxane-2-carbonyl)piperazine (Doxazosin EP Impurity C) is an impurity in the synthesis of Doxazosin (D537500), a selective a1-adrenoceptor antagonist. Doxazosin relaxes smooth muscles of the prostate.
References:Elliott, H.L., et al.: Brit. J. Clin. Pharmacol., 13, 699 (1982), de Leeuw, P.W., et al.: Eur. J. Clin. Pharmacol., 23, 397 (1982),
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